Observations of Mercury's magnetic field

Magnetic field data obtained by Mariner 10 during the third and final encounter with the planet Mercury on 16 March 1975 were studied. A well developed bow shock and modest magnetosphere, previously observed at first encounter on 29 March 1974, were again observed. In addition, a much stronger magnetic field near closest approach, 400 gamma versus 98 gamma, was observed at an altitude of 327 km and approximately 70 deg north Mercurian latitude. Spherical harmonic analysis of the data provide an estimate of the centered planetary magnetic dipole of 4.7 x 10 to the 22nd power Gauss/cu cm with the axis tilted 12 deg to the rotation axis and in the same sense as Earth's. The interplanetary field was sufficiently different between first and third encounters that in addition to the very large field magnitude observed, it argues strongly against a complex induction process generating the observed planetary field. While a possibility exists that Mercury possesses a remanent field due to magnetization early in its formation, a present day active dynamo seems to be a more likely candidate for its origin

Magnetic field of Mercury confirmed

A contention that Mercury possesses an intrinsic magnetic field sufficient to deflect the solar wind flow was confirmed by the Mariner 10 experiment. Predictions made as to the locations where characteristic bow shock and magnetopause boundaries may be observed were also confirmed

The magnetic field of Mercury, part 1

An updated analysis and interpretation is presented of the magnetic field observations obtained during the Mariner 10 encounter with the planet Mercury. The combination of data relating to position of the detached bow shock wave and magnetopause, and the geometry and magnitude of the magnetic field within the magnetosphere-like region surrounding Mercury, lead to the conclusion that an internal planetary field exists with dipole moment approximately 5.1 x 10 the 22nd power Gauss sq cm. The dipole axis has a polarity sense similar to earth's and is tilted 7 deg from the normal to Mercury's orbital plane. The magnetic field observations reveal a significant distortion of the modest Hermean field (350 Gamma at the equator) by the solar wind flow and the formation of a magnetic tail and neutral sheet which begins close to the planet on the night side. The composite data is not consistent with a complex induction process driven by the solar wind flow

Interaction of solar wind with Mercury and its magnetic field

A brief review is presented of magnetic field and solar wind electron observations by Mariner 10 spacecraft. The intrinsic magnetic field of the planet Mercury and the implications of such a field for the planetary interior are also discussed

Magnetic field observations near Mercury: Preliminary results from Mariner 10

Results are presented from a preliminary analysis of data obtained near Mercury by the NASA/GSFC Magnetic Field Experiment on Mariner 10. A very well developed, detached bow shock wave, which developed as the super-Alfvenic solar wind interacted with the planet Mercury was observed. A magnetosphere-like region, with maximum field strength of 98 gamma at closest approach (704 km altitude) was also observed, and was contained within boundaries similar to the terrestrial magnetopause. The obstacle deflecting the solar wind flow was global in size, but the origin of the enhanced magnetic field was not established. The most plausible explanation, considering the complete body of data, favored the conclusion that Mercury has an intrinsic magnetic field

Phase II trial of intrapleural paclitaxel injection for non-small-cell lung cancer patients with malignant pleural effusions

AbstractA phase II clinical trial of intrapleural paclitaxel injection for malignant effusions of non-small-cell lung cancer (NSCLC) was conducted in order to evaluate the efficacy and toxicity profile of paclitaxel pleurodesis in patients with malignant effusions. From February to May of 1996, 15 NSCLC patients with malignant pleural effusions were enrolled on study. After adequate drainage and assurance of lung re-expansion, paclitaxel 125 mg m−2 diluted in normal saline was infused through a preinserted pig-tail catheter which was removed 2 h later. Chest radiography and sonography were scheduled 4 days later; depending on whether there remained a significant amount of pleural effusion, further drainage by needle thoracentesis or by a pig-tail catheter was performed.All patients were assessable for toxicity. Ipsilateral chest and/or shoulder pain, fever, facial flushing and nausea were the most frequent side-effects. Grade 4 neutropenia, grade 3 anaemia, and grade 3 renal impairment occurred in one patient each. Fourteen patients were evaluable for response at the end of the fourth week. Overall response rate of pleural effusion in evaluable patients was 92·9%, with a complete response rate of 28·6%. There was one out of 14 evaluable patients whose measurable tumour lesion decreased by more than 50% (partial response). No disease progression was noted among evaluable patients at the end of the fourth week. It is concluded that paclitaxel is a useful agent for the treatment of malignant pleural effusions. Because of its relatively low systemic toxicity, intrapleural paclitaxel injection in combination with systemic chemotherapy or radiotherapy can be considered in treating NSCLC patients with malignant pleural effusions

Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase

BACKGROUND: Telomeres consist of repetitive (TTAGGG) DNA sequences that are maintained by the multisubunit telomerase ribonucleoprotein. Telomerase consists of an RNA, which serves as template for the sequence tracts, and a catalytic subunit that functions in reverse transcription of the RNA template. Cloning and characterization of the human catalytic subunit of telomerase (hTERT) has supported a role in cell transformation. How telomerase activity is regulated, however, is largely unknown. RESULTS: We show here that hTERT associates directly with the c-Abl protein tyrosine kinase. We also found that c-Abl phosphorylates hTERT and inhibits hTERT activity. Moreover, our findings demonstrate that exposure of cells to ionizing radiation induces tyrosine phosphorylation of hTERT by a c-Abl-dependent mechanism. The functional significance of the c-Abl-hTERT interaction is supported by the demonstration that cells deficient in c-Abl show telomere lengthening. CONCLUSIONS: The ubiquitously expressed c-Abl tyrosine kinase is activated by DNA double-strand breaks. Our finding of telomere lengthening in c-Abl-deficient cells and the functional interactions between c-Abl and hTERT support a role for c-Abl in the regulation of telomerase function

Coccydynia

Coccydynia is a term that refers to pain in the region of the coccyx. Most cases are associated with abnormal mobility of the coccyx which may trigger a chronic inflammatory process leading to degeneration of this structure. In some patients this instability may be detected on dynamic radiographs. Nonsurgical management remains the gold standard treatment for coccydynia, consisting of decreased sitting, seat cushioning, coccygeal massage, stretching, manipulation, local injection of steroids or anesthetics, and postural adjustments. Those patients who fail these conservative modalities may potentially benefit from coccygectomy. However, surgical intervention is typically reserved for patients with evidence of advanced coccygeal instability (e.g., subluxation or hypermobility) or spicule formation, as this population appears to exhibit the greatest improvement postoperatively

Body Appreciation as a Means to Protect Social Media Users from Body Dissatisfaction

When young adult women and men are exposed to idealized images in traditional media outlets, they often experience body dissatisfaction. As the use of social media increases, so do the opportunities for appearance-based comparisons. Individuals who are heavy users of social networking sites also tend to exhibit body dissatisfaction. Body appreciation is a personal characteristic that seems to counteract the negative influence traditional media exposure, and it may have a similar effect for social media exposure. The purpose of our research was to investigate the impact of body appreciation on the relationship between social network sites usage and body dissatisfaction with young adult women and men. An online survey method was employed to collect the data. Participants, who were recruited using Amazon Mechanical Turk, completed a questionnaire featuring previously developed scales. The multi-item scales featured seven-point, Likert-type items. The data were analyzed using the two-step approach to structural equation modeling. The structural model was used to test the hypotheses. All of the hypotheses were supported. Social networking sites usage was positively related to body dissatisfaction. Fortunately, though, body appreciation did reduce body dissatisfaction as a moderating variable. Because usage of social networking sites is ubiquitous in today’s society, understanding the impact that these sites have on users is important. Our findings indicate that negative outcomes, such as body dissatisfaction, can occur as a result of social networking sites usage. Uncovering ways to limit these negative outcomes, including increasing body appreciation, is vital for young adults’ mental health

Massive Charged Scalar Quasinormal Modes of Reissner-N\"ordstrom Black Hole Surrounded by Quintessence

We evaluate the complex frequencies of the normal modes for the massive charged scalar field perturbations around a Reissner-N\"ordstrom black hole surrounded by a static and spherically symmetric quintessence using third order WKB approximation approach. Due to the presence of quintessence, quasinormal frequencies damp more slowly. We studied the variation of quasinormal frequencies with charge of the black bole, mass and charge of perturbating scalar field and the quintessential state parameter.Comment: 9 pages, 9 figures and one tabl