20 research outputs found
Whole Genome Sequencing in Psychiatric Disorders: the WGSPD Consortium
As technology advances, whole genome sequencing (WGS) is likely to supersede other genotyping technologies. The rate of this change depends on its relative cost and utility. Variants identified uniquely through WGS may reveal novel biological pathways underlying complex disorders and provide high-resolution insight into when, where, and in which cell type these pathways are affected. Alternatively, cheaper and less computationally intensive approaches may yield equivalent insights. Understanding the role of rare variants in the noncoding gene-regulating genome, through pilot WGS projects, will be critical to determine which of these two extremes best represents reality. With large cohorts, well-defined risk loci, and a compelling need to understand the underlying biology, psychiatric disorders have a role to play in this preliminary WGS assessment. The WGSPD consortium will integrate data for 18,000 individuals with psychiatric disorders, beginning with autism spectrum disorder, schizophrenia, bipolar disorder, and major depressive disorder, along with over 150,000 controls
Effects of Cover Crops on Pratylenchus penetrans and the Nematode Community in Carrot Production
Appendix G. Figure showing the nonlinear relationship between habitat diversity and proportion soybean in the landscape.
Figure showing the nonlinear relationship between habitat diversity and proportion soybean in the landscape
Appendix F. Table with the bootstrapped standardized and unstandardized path coefficients for the SEM models.
Table with the bootstrapped standardized and unstandardized path coefficients for the SEM models
Appendix C. Figure showing the temporal variation of soybean aphids and natural enemies in 2011 and 2012.
Figure showing the temporal variation of soybean aphids and natural enemies in 2011 and 2012
Appendix E. Figure of the yearly variation in natural enemy abundances and soybean yield gain.
Figure of the yearly variation in natural enemy abundances and soybean yield gain
Appendix H. Figure showing the nonlinear relationship between aphid abundance and soybean yield in 2011 and 2012.
Figure showing the nonlinear relationship between aphid abundance and soybean yield in 2011 and 2012
Appendix B. Maps of experimental soybean fields in Wisconsin and Michigan.
Maps of experimental soybean fields in Wisconsin and Michigan
Appendix A. Detailed sampling protocols 2011 and 2012.
Detailed sampling protocols 2011 and 2012
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Publisher Correction: Whole genome sequencing in psychiatric disorders: the WGSPD consortium.
In the version of this article initially published, the consortium authorship and corresponding authors were not presented correctly. In the PDF and print versions, the Whole Genome Sequencing for Psychiatric Disorders (WGSPD) consortium was missing from the author list at the beginning of the paper, where it should have appeared as the seventh author; it was present in the author list at the end of the paper, but the footnote directing readers to the Supplementary Note for a list of members was missing. In the HTML version, the consortium was listed as the last author instead of as the seventh, and the line directing readers to the Supplementary Note for a list of members appeared at the end of the paper under Author Information but not in association with the consortium name itself. Also, this line stated that both member names and affiliations could be found in the Supplementary Note; in fact, only names are given. In all versions of the paper, the corresponding author symbols were attached to A. Jeremy Willsey, Steven E. Hyman, Anjene M. Addington and Thomas Lehner; they should have been attached, respectively, to Steven E. Hyman, Anjene M. Addington, Thomas Lehner and Nelson B. Freimer. As a result of this shift, the respective contact links in the HTML version did not lead to the indicated individuals. The errors have been corrected in the HTML and PDF versions of the article