Using Broad Phonetic Group Experts for Improved Speech Recognition

In phoneme recognition experiments, it was found that approximately 75% of misclassified frames were assigned labels within the same broad phonetic group (BPG). While the phoneme can be described as the smallest distinguishable unit of speech, phonemes within BPGs contain very similar characteristics and can be easily confused. However, different BPGs, such as vowels and stops, possess very different spectral and temporal characteristics. In order to accommodate the full range of phonemes, acoustic models of speech recognition systems calculate input features from all frequencies over a large temporal context window. A new phoneme classifier is proposed consisting of a modular arrangement of experts, with one expert assigned to each BPG and focused on discriminating between phonemes within that BPG. Due to the different temporal and spectral structure of each BPG, novel feature sets are extracted using mutual information, to select a relevant time-frequency (TF) feature set for each expert. To construct a phone recognition system, the output of each expert is combined with a baseline classifier under the guidance of a separate BPG detector. Considering phoneme recognition experiments using the TIMIT continuous speech corpus, the proposed architecture afforded significant error rate reductions up to 5% relative

Interface stoichiometry control to improve device voltage and modify band alignment in ZnO/Cu_2O heterojunction solar cells

The interface stoichiometry of cuprous oxide (Cu_2O) was controlled by adjusting the O_2 and Zn partial pressures during ZnO sputter deposition and measured by high-resolution X-ray photoelectron spectroscopy of ultrathin (<3 nm) ZnO films on Cu_2O. Open-circuit voltage measurements for ZnO/Cu_2O heterojunctions under AM1.5 illumination were measured and it was found that a stoichiometric interface can achieve the voltage entitlement dictated by the band alignment, whereas the non-stoichiometric interface showed large open-circuit voltage deficits. These results highlight not only the need for stoichiometric interfaces in Cu_2O devices, but also a reproducible experimental method for achieving stoichiometric interfaces that could be applied to any potential heterojunction partner. Additionally, valence-band offset measurements indicated changing the interface stoichiometry shifted the band alignment between Cu_2O and ZnO, which accounts for the variation in previously reported band offset values

South-to-North Water Diversion stabilizing Beijing’s groundwater levels

Groundwater (GW) overexploitation is a critical issue in North China with large GW level declines resulting in urban water scarcity, unsustainable agricultural production, and adverse ecological impacts. One approach to addressing GW depletion was to transport water from the humid south. However, impacts of water diversion on GW remained largely unknown. Here, we show impacts of the central South-to-North Water Diversion on GW storage recovery in Beijing within the context of climate variability and other policies. Water diverted to Beijing reduces cumulative GW depletion by ~3.6 km3, accounting for 40% of total GW storage recovery during 2006-2018. Increased precipitation contributes similar volumes to GW storage recovery of ~2.7 km3 (30%) along with policies on reduced irrigation (~2.8 km3, 30%). This recovery is projected to continue in the coming decade. Engineering approaches, such as water diversions, will increasingly be required to move towards sustainable water management

South-to-North Water Diversion stabilizing Beijing’s groundwater levels

Groundwater (GW) overexploitation is a critical issue in North China with large GW level declines resulting in urban water scarcity, unsustainable agricultural production, and adverse ecological impacts. One approach to addressing GW depletion was to transport water from the humid south. However, impacts of water diversion on GW remained largely unknown. Here, we show impacts of the central South-to-North Water Diversion on GW storage recovery in Beijing within the context of climate variability and other policies. Water diverted to Beijing reduces cumulative GW depletion by ~3.6 km3, accounting for 40% of total GW storage recovery during 2006-2018. Increased precipitation contributes similar volumes to GW storage recovery of ~2.7 km3 (30%) along with policies on reduced irrigation (~2.8 km3, 30%). This recovery is projected to continue in the coming decade. Engineering approaches, such as water diversions, will increasingly be required to move towards sustainable water management

Mendelian and Non-Mendelian Regulation of Gene Expression in Maize

Transcriptome variation plays an important role in affecting the phenotype of an organism. However, an understanding of the underlying mechanisms regulating transcriptome variation in segregating populations is still largely unknown. We sought to assess and map variation in transcript abundance in maize shoot apices in the intermated B73×Mo17 recombinant inbred line population. RNA-based sequencing (RNA-seq) allowed for the detection and quantification of the transcript abundance derived from 28,603 genes. For a majority of these genes, the population mean, coefficient of variation, and segregation patterns could be predicted by the parental expression levels. Expression quantitative trait loci (eQTL) mapping identified 30,774 eQTL including 96 trans-eQTL "hotspots," each of which regulates the expression of a large number of genes. Interestingly, genes regulated by a trans-eQTL hotspot tend to be enriched for a specific function or act in the same genetic pathway. Also, genomic structural variation appeared to contribute to cis-regulation of gene expression. Besides genes showing Mendelian inheritance in the RIL population, we also found genes whose expression level and variation in the progeny could not be predicted based on parental difference, indicating that non-Mendelian factors also contribute to expression variation. Specifically, we found 145 genes that show patterns of expression reminiscent of paramutation such that all the progeny had expression levels similar to one of the two parents. Furthermore, we identified another 210 genes that exhibited unexpected patterns of transcript presence/absence. Many of these genes are likely to be gene fragments resulting from transposition, and the presence/absence of their transcripts could influence expression levels of their ancestral syntenic genes. Overall, our results contribute to the identification of novel expression patterns and broaden the understanding of transcriptional variation in plants. © 2013 Lin et al

TRH: Pathophysiologic and clinical implications

Thyrotropin releasing hormone is thought to be a tonic stimulator of the pituitary TSH secretion regulating the setpoint of the thyrotrophs to the suppressive effect of thyroid hormones. The peptide stimulates the release of normal and elevated prolactin. ACTH and GH may increase in response to exogenous TRH in pituitary ACTH and GH hypersecretion syndromes and in some extrapituitary diseases. The pathophysiological implications of extrahypothalamic TRH in humans are essentially unknown. The TSH response to TRH is nowadays widely used as a diganostic amplifier in thyroid diseases being suppressed in borderline and overt hyperthyroid states and increased in primary thyroid failure. In hypothyroid states of hypothalamic origin, TSH increases in response to exogenous TRH often with a delayed and/or exaggerated time course. But in patients with pituitary tumors and suprasellar extension TSH may also respond to TRH despite secondary hypothyroidism. This TSH increase may indicate a suprasellar cause for the secondary hypothyroidism, probably due to portal vessel occlusion. The TSH released in these cases is shown to be biologically inactive

Planform selection in two-layer Benard-Marangoni convection

Benard-Marangoni convection in a system of two superimposed liquids is investigated theoretically. Extending previous studies the complete hydrodynamics of both layers is treated and buoyancy is consistently taken into account. The planform selection problem between rolls, squares and hexagons is investigated by explicitly calculating the coefficients of an appropriate amplitude equation from the parameters of the fluids. The results are compared with recent experiments on two-layer systems in which squares at onset have been reported.Comment: 17 pages, 7 figures, oscillatory instability included, typos corrected, references adde