101 research outputs found
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Design and synthesis of differentially functionalized amphiphilic dendrimer.
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Dendrimers based on a three-dimensionally disposed AB(4) monomer
[reaction: see text] Design and synthesis of a novel class of dendrons based on an AB(4) monomer are described. These dendrons have been evaluated by using dendritic encapsulation of a redox active core. The electrochemical properties of symmetric ferrocene-cored dendrimers show that significant alterations in redox potential and heterogeneous electron-transfer rate constants could be achieved even at lower generations
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Design and synthesis of differentially functionalized amphiphilic dendrimer.
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Towards dendrimers as biomimetic macromolecules
Dendrimers can be obtained in precise molecular weights even at high generations. This feature, as well as the inherent globular shape of high generation dendrimers, makes them ideal candidates for macromolecular biomimetics. In this account, we discuss the synthesis and use of dendrimers that are reminiscent of macromolecular architectures present in nature. In particular, we focus the use of dendrimers in the areas of encapsulation, functionalization, and sequencing
<b style="">Antibacterial activity of some ethnomedicinal plants from the Nilgiris,</b> <b style="">Tamil Nadu, India</b>
34-39The present investigation encompasses antibacterial potential of three medicinal
plants used by the tribals of Nilgiris for the treatment of various skin
ailments. About 18 extracts at three concentrations (10, 5, 2.5 mg/ml) of
different plant parts of Siegesbeckia orientalis Linn., Berberis tinctoria Lesch. and Justicia betonica Linn. were tested against pathogenic
bacteria, viz. Aeromonas hydrophila,
Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella
typhi, Salmonella sp., Staphylococcus
aureus, Vibrio cholerae and V. parahemolyticus. All the extracts
exhibited broader antibacterial activity against the tested pathogens
Bacterial fauna associating with chironomid larvae from lakes of Bengaluru city, India - A 16s rRNA gene based identification
Chironomid larvae that inhabit in aquatic sediments play an important role as vector for bacterial pathogens. Its life cycle consists of four stages i.e. eggs, larvae, pupae and adult. In the present study we identified bacterial species associated with whole larvae of chironomids from 11 lake sediments of Bangalore region using 16s rRNA gene Sanger sequencing. We found that larvae from all lake sediments associated with bacterial species which include key pathogens. Totally we identified 65 bacterial isolates and obtained GenBank accession numbers (KX980423 - KX980487). Phylogenetic tree constructed using MEGA 7 software and tree analysis highlight the predominant bacterial community associated with larvae which include Enterobacteriaceae (43.08%; 28 isolates) and Aeromonas (24.62%; 16 isolates), Shewanella, Delftia, Bacillus (6.15%; 4 isolates each), Pseudomonas (4.62%; 3 isolates) and Exiguobacterium (3.08%; 2 isolates). Current findings state that among bacterial population Aeromonas, Enterobacter and Escherichia with serotypes are commonly associated with larvae in maximum lake points. In other hand Vibrio, Pseudomonas, Klebsiella, Shigella, Bacillus, and other bacterial species were identified moderately in all lakes. Interestingly, we identified first time Shigella Gram negative, rod shaped pathogenic organism of Enterobacteriaceae and Rheinheimera Gram negative, rod shaped organism associating chironomid larvae
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