Skeletal, dental and profilometric effects of Sabbagh Universal Spring 2 (SUS2) in a patient at the end of growth: a case report

Introduction: Malocclusions, which present a severe skeletal component, are difficult to solve through orthodontic treatment inpatients at the end of growth and often require a combined orthodontic-surgical treatment. The mandibular propulsion appliances "no compliance" now offer new possibilities for functional orthopedic treatment in borderline cases. Case presentation: A patient at the end of growth with a severe malocclusion (Class II Division 1), open bite with arches\u27 transversaldiscrepancy, refused the hypothesis of an orthodontic-surgical treatment, which represents the gold standard in such occlusal andskeletal problems, especially in subjects at the end of growth; consequently, a complex orthopedic-orthodontic treatment was chosen as the second choice. The patient has been successfully treated also through the use of SUS2 (Sabbagh Universal Spring 2; Dentaurum, Ispringen, Germany), a "no compliance" fixed functional appliance, which carried out a significant sagittal correction. Conclusion: The case report especially highlights the important sagittal correction obtained through the use of SUS2. The SUS2 had a functional outcome, which resulted in the maxillary growth stop and an effective sagittal mandibular growth increase. The SUS2effects, enhanced by elastics biomechanics, led to the bite closure and at the achievement of Class I occlusion

Data from a multidisciplinary poll of 178 expert physicians on the usage of non-vitamin K Oral Anticoagulants in patients with atrial fibrillation and venous thromboembolism

This data article contains data from a multidisciplinary questionnaires filled in by 178 expert physicians on the usage of non-vitamin K Oral Anticoagulants in patients with atrial fibrillation (AF) and for the treatment of patients with venous thromboembolism (VTE). The questionnaire consists of 9 statements of clinical complex AF and VTE cases and informative campaign on antithrombotic therapy for stroke prevention in AF. The data are potentially valuable for the scientific community, showing the doubts of different specialists (Internists, Pneumologists, Geriatricians, Cardiologists and Neurologists) with a large experience in prescribing oral anticoagulation in difficult AF and VTE cases (see full list of participants provided). The data obtained in some particular clinical cases such as CHA2DS2-VASc=1, comorbid coronary artery disease, frailty, advanced age, risk of falling and prior haemorrhagic stroke, can be compared with indications from published guidelines and recommendations for future insight and to be considered as a benchmark for future trials in the area or oral anticoagulation for AF and VTE.The data concerning informative campaign on antithrombotic therapy for stroke prevention showed the expert panel agreement on the inclusion of self monitoring of heart rhythm by pulse taking in subjects older than 64 years of age (81% agreement, item 3); knowledge that the risk of stroke associated with AF is almost twice the risk associated with hypertension (95% agreement, item 4); knowledge that the CHA2DS2-VASc score exerts a higher influence on stroke risk compared to AF duration (92% agreement, item 5); knowledge that stroke prevention in AF with a NOAC is more effective, does not cause any higher bleeding risk, and is equally simple compared to aspirin treatment (91% agreement, item 6).Data on strategies to optimise appropriate prescription of antithrombotic therapy showed agreement on the utility of short television advertisements about the risks of stroke associated with AF (79% agreement, item 8), on a campaign encouraging regular control of cardiac rhythm by pulse taking (77% agreement, item 1), on a campaign reporting the advantages of anticoagulation over no antithrombotic therapy (98% agreement, item 2) or of NOACs over aspirin (96% agreement, item 3) or on the practical use of NOAC (93% agreement, item 6) or on stroke and bleeding risk scores (87% agreement, item 7). See Colonna et al. (2017) [1] for further interpretation and discussion

Giant Liquid Argon Observatory for Proton Decay, Neutrino Astrophysics and CP-violation in the Lepton Sector (GLACIER)

GLACIER (Giant Liquid Argon Charge Imaging ExpeRiment) is a large underground observatory for proton decay search, neutrino astrophysics and CP-violation studies in the lepton sector. Possible underground sites are studied within the FP7 LAGUNA project (Europe) and along the JPARC neutrino beam in collaboration with KEK (Japan). The concept is scalable to very large masses.Comment: 4 pages, 1 figure, Contribution to the Workshop "European Strategy for Future Neutrino Physics", CERN, Oct. 200

Beam-Based Alignment of the NuMI Target Station Components at FNAL

The Neutrinos at the Main Injector (NuMI) facility is a conventional horn-focused neutrino beam which produces muon neutrinos from a beam of mesons directed into a long evacuated decay volume. The relative alignment of the primary proton beam, target, and focusing horns affects the neutrino energy spectrum delivered to experiments. This paper describes a check of the alignment of these components using the proton beam.Comment: higher resolution figures available on Fermilab Preprint Server (see SPIRES entry), accepted for publication in Nucl. Instr. and Meth.

Patient Self-Harm in the Emergency Department: An Evidence- Based Approach

Violence, deliberate self harm, and suicide in emergency departments and hospitals is likely to remain a significant problem for health care systems well into the future. Understanding how to confront, intervene, and manage episodes of patient deliberate self harm is extremely important, and can be life-saving. Here, through a clinical vignette, and a discussion of deliberate self harm we will highlight the importance of the direct observation of such patients, containment procedures (seclusion and physical restraints), and the use of pharmacological adjuncts. We hope that this concise, practically-oriented review will provide our readers with foundational understanding of the topic, including the most important theoretical and clinical considerations