956 research outputs found
Quantum-limited directional amplifiers with optomechanics
Directional amplifiers are an important resource in quantum information
processing, as they protect sensitive quantum systems from excess noise. Here,
we propose an implementation of phase-preserving and phase-sensitive
directional amplifiers for microwave signals in an electromechanical setup
comprising two microwave cavities and two mechanical resonators. We show that
both can reach their respective quantum limits on added noise. In the reverse
direction, they emit thermal noise stemming from the mechanical resonators and
we discuss how this noise can be suppressed, a crucial aspect for technological
applications. The isolation bandwidth in both is of the order of the mechanical
linewidth divided by the amplitude gain. We derive the bandwidth and
gain-bandwidth product for both and find that the phase-sensitive amplifier has
an unlimited gain-bandwidth product. Our study represents an important step
toward flexible, on-chip integrated nonreciprocal amplifiers of microwave
signals
Hysteresis and bi-stability by an interplay of calcium oscillations and action potential firing
Many cell types exhibit oscillatory activity, such as repetitive action
potential firing due to the Hodgkin-Huxley dynamics of ion channels in the cell
membrane or reveal intracellular inositol triphosphate (IP) mediated
calcium oscillations (CaOs) by calcium-induced calcium release channels
(IP-receptor) in the membrane of the endoplasmic reticulum (ER). The
dynamics of the excitable membrane and that of the IP-mediated CaOs have
been the subject of many studies. However, the interaction between the
excitable cell membrane and IP-mediated CaOs, which are coupled by
cytosolic calcium which affects the dynamics of both, has not been studied.
This study for the first time applied stability analysis to investigate the
dynamic behavior of a model, which includes both an excitable membrane and an
intracellular IP-mediated calcium oscillator. Taking the IP
concentration as a control parameter, the model exhibits a novel rich spectrum
of stable and unstable states with hysteresis. The four stable states of the
model correspond in detail to previously reported growth-state dependent states
of the membrane potential of normal rat kidney fibroblasts in cell culture. The
hysteresis is most pronounced for experimentally observed parameter values of
the model, suggesting a functional importance of hysteresis. This study shows
that the four growth-dependent cell states may not reflect the behavior of
cells that have differentiated into different cell types with different
properties, but simply reflect four different states of a single cell type,
that is characterized by a single model.Comment: 29 pages, 6 figure
Using local and historical data to enhance understanding of spatial and temporal rainfall patterns
Farmers face uncertainty in their businesses from many factors, but rainfall is a key determinant of both the nature of the production system and variation in financial returns. Currently, various weather forecasting services are available from the Australian Bureau of Meteorology (BoM) based on about 7000 stations covering all of Australia. Seasonal Climate Forecasts are seen as another tool that can help to improve farm productivity. It is well known that many farmers keep their own rainfall records, and likely that the farmers have a high degree of confidence in their own records. Australian Bureau of Statistics figures indicate that there were possibly 7000 grain related ‘agricultural businesses’ in NSW alone in 2009/10 indicating that there is the potential to increase data density by up to an order of magnitude. This project is part of a broader study to improve rainfall predictions for grain farmers using data collected locally to the users (crowd sourcing). The data is collected directly on farm, and from other sources which may be available. The focus is on the historical data, its collection and analysis, in terms of discerning patterns in time and space which may help provide a local framework, within which coarser scale forecasts can be interpreted and understood. Data will be stored on secure database systems at the University of Sydney. Results indicate that farm data does provide more local detail, temporally and spatially. Deficit and surplus analysis demonstrates the predictive capacity of the local temporal data, despite limited data precluding the definition of ideal criteria and parameters for predictive ‘similar year’ selection. The spatial data demonstrates quantifiable site specific differences from institutional data. Testing across more climate types may allow these differences to be defined within and across regions. Tests for an indicator time period show that farm rainfall in the early part of the growing season (April and May) may indeed be indicative of seasonal condtions, while more data is needed to confirm this. The use of southern oscillation life cycle information to select appropriate years considerably improved the relationships revealed, with a doubling of relationship strength across all climatic types, although the strength of the relationships differed across the climatic types, and the strongest relationships were split between the months of April and May. More extensive analysis, with more data across more BoM districts (and therefore climate classes) will be required to confirm this conclusion, but it appears that farm rainfall records and SOI information can provide an indicator time period to help farmers interpret, refine and utilise seasonal forecasts
Dynamical Landau-de Gennes Theory for Electrically-Responsive Liquid Crystal Networks
Liquid crystal networks combine the orientational order of liquid crystals
with the elastic properties of polymer networks, leading to a vast application
potential in the field of responsive coatings, e.g., for haptic feedback,
self-cleaning surfaces and static and dynamic pattern formation. Recent
experimental work has further paved the way toward such applications by
realizing the fast and reversible surface modulation of a liquid crystal
network coating upon in-plane actuation with an AC electric field. Here, we
construct a Landau-type theory for electrically-responsive liquid crystal
networks and perform Molecular Dynamics simulations to explain the findings of
these experiments and inform on rational design strategies. Qualitatively, the
theory agrees with our simulations and reproduces the salient experimental
features. We also provide a set of testable predictions: the aspect ratio of
the nematogens, their initial orientational order when cross-linked into the
polymer network and the cross-linking fraction of the network all increase the
plasticization time required for the film to macroscopically deform. We
demonstrate that the dynamic response to oscillating electric fields is
characterized by two resonances, which can likewise be influenced by varying
these parameters, providing an experimental handle to fine-tune device design
A globally efficient means of distributing UTC time and frequency through GPS
Time and frequency outputs comparable in quality to the best laboratories have been demonstrated on an integrated system suitable for field application on a global basis. The system measures the time difference between 1 pulse-per-second (pps) signals derived from local primary frequency standards and from a multi-channel GPS C/A receiver. The measured data is processed through optimal SA Filter algorithms that enhance both the stability and accuracy of GPS timing signals. Experiments were run simultaneously at four different sites. Even with large distances between sites, the overall results show a high degree of cross-correlation of the SA noise. With sufficiently long simultaneous measurement sequences, the data shows that determination of the difference in local frequency from an accepted remote standard to better than 1 x 10(exp -14) is possible. This method yields frequency accuracy, stability, and timing stability comparable to that obtained with more conventional common-view experiments. In addition, this approach provides UTC(USNO MC) in real time to an accuracy better than 20 ns without the problems normally associated with conventional common-view techniques. An experimental tracking loop was also set up to demonstrate the use of enhanced GPS for dissemination of UTC(USNO MC) over a wide geographic area. Properly disciplining a cesium standard with a multi-channel GPS receiver, with additional input from USNO, has been found to permit maintaining a timing precision of better than 10 ns between Palo Alto, CA and Washington, DC
Double Exchange Alone Does Not Explain the Resistivity of
The system with has
traditionally been modelled with a ``double exchange'' Hamiltonian, in which it
is assumed that the only relevant physics is the tendency of carrier hopping to
line up neighboring spins. We present a solution of the double exchange model,
show it is incompatible with many aspects of the resistivity data, and propose
that a strong electron-phonon interaction arising from a Jahn-Teller splitting
of the outer Mn d-level plays a crucial role.Comment: Figure available via concentional mail. Contact
[email protected]
Expression profiling of immune inhibitory Siglecs and their ligands in patients with glioma
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