327 research outputs found
Electrovibrostimulation during the training of sportsmen, an experimental set-up
In this study the effects of electrovibrostimulation training are compared with classical powertraining, in a group of 18-24 years old healthy sportsmen, during the spring season of 2007. Former studies showed the effectiveness of electrovibrostimulation on the functional condition of muscles: increase of the strength in the active insufficiency zone and increase of the elasticity in the passive insufficiency zone, consequently improving joint strength and mobility. After four weeks of electrovibrostimulation, applied twice a week, significant increases of isometric strength and explosive strength were observed, whereas the flexibility remained the same. Some hypotheses are discussed concerning the possible working mechanisms of electrovibrostimulatio
Probabilistic abstract interpretation: From trace semantics to DTMC’s and linear regression
In order to perform probabilistic program analysis we need to consider probabilistic languages or languages with a probabilistic semantics, as well as a corresponding framework for the analysis which is able to accommodate probabilistic properties and properties of probabilistic computations. To this purpose we investigate the relationship between three different types of probabilistic semantics for a core imperative language, namely Kozen’s Fixpoint Semantics, our Linear Operator Semantics and probabilistic versions of Maximal Trace Semantics. We also discuss the relationship between Probabilistic Abstract Interpretation (PAI) and statistical or linear regression analysis. While classical Abstract Interpretation, based on Galois connection, allows only for worst-case analyses, the use of the Moore-Penrose pseudo inverse in PAI opens the possibility of exploiting statistical and noisy observations in order to analyse and identify various system properties
Pervasiveness of the IQ Rise: A Cross-Temporal Meta-Analysis
Background: Generational IQ gains in the general population (termed the Flynn effect) show an erratic pattern across different nations as well as across different domains of intelligence (fluid vs crystallized). Gains of fluid intelligence in different countries have been subject to extensive research, but less attention was directed towards gains of crystallized intelligence, probably due to evidence from the Anglo-American sphere suggesting only slight gains on this measure. In the present study, development of crystallized intelligence in the German speaking general population is assessed. Methodology/Principal Findings: To investigate whether IQ gains for crystallized intelligence are in progress in Germanspeaking countries, two independent meta-analyses were performed. By means of a cited reference search in ISI Web of Science, all studies citing test manuals and review articles of two widely-used salient measures of crystallized intelligence were obtained. Additionally, the electronic database for German academic theses was searched to identify unpublished studies employing these tests. All studies reporting participants mean IQ or raw scores of at least one of the two measures were included in the present analyses, yielding over 500 studies (.1,000 samples;.45,000 individuals). We found a significant positive association between years of test performance and intelligence (1971–2007) amounting to about 3.5 IQ points per decade. Conclusions/Significance: This study clearly demonstrates that crystallized IQ gains are substantial and of comparabl
Impact of environmental and genetic factors on the scale shape of zebrafish, Danio rerio (Hamilton 1822): A geometric morphometric study
Intraspecific morphological variability may reflect either genetic divergence among groups of individuals or response of individuals to environmental circumstances within the frame of phenotypic plasticity. Several studies were able to discriminate wild fish populations based on their scale shape. Here we examine whether the variations in the scale shape in fish populations could be related to genetic or environmental factors, or to both of them. In the first experiment, two inbred lines of zebrafish Danio rerio (Hamilton 1822) reared under identical environmental conditions were compared. Secondly, to find out what effect environmental factors might have, offsprings were divided into two groups and reared on different diets for 12 weeks. Potential recovery of scales from an environmental effect was also assessed. Experimental groups could successfully be distinguished according to the shape of scales in both experiments, and the results showed that both genetic and environmental factors may notably influence scale shape. It was concluded that scale shape analysis might be used as an explanatory tool to detect potential variability of environmental influences impacting genetically homogeneous groups of fish. However, due to its sensitivity to environmental heterogeneity, the applicability of this technique in identifying intraspecific stock membership of fish could be limited
Rasch analysis of the Patient and Observer Scar Assessment Scale (POSAS) in burn scars
The Patient and Observer Scar Assessment Scale (POSAS) is a questionnaire that was developed to assess scar quality. It consists of two separate six-item scales (Observer Scale and Patient Scale), both of which are scored on a 10-point rating scale. After many years of experience with this scale in burn scar assessment, it is appropriate to examine its psychometric properties using Rasch analysis. Cross-sectional data collection from seven clinical trials resulted in a data set of 1,629 observer scores and 1,427 patient scores of burn scars. We examined the person-item map, item fit statistics, reliability, response category ordering, and dimensionality of the POSAS. The POSAS showed an adequate fit to the Rasch model, except for the item surface area. Person reliability of the Observer Scale and Patient Scale was 0.82 and 0.77, respectively. Dimensionality analysis revealed that the unexplained variance by the first contrast of both scales was 1.7 units. Spearman correlation between the Observer Scale Rasch measure and the overall opinion of the clinician was 0.75. The Rasch model demonstrated that the POSAS is a reliable and valid scale that measures the single-construct scar qualit
An Expanded Multi-scale Monte Carlo Simulation Method for Personalized Radiobiological Effect Estimation in Radiotherapy: a feasibility study
A novel and versatile “bottom-up� approach is developed to estimate the radiobiological effect of clinic
radiotherapy. The model consists of multi-scale Monte Carlo simulations from organ to cell levels. At cellular level, accumulated damages are computed using a spectrum-based accumulation algorithm and predefined cellular damage database. The damage repair mechanism is modeled by an expanded reaction-rate two-lesion kinetic model, which were calibrated through replicating a radiobiological experiment. Multi-scale modeling is then performed on a lung cancer patient under conventional fractionated irradiation. The cell killing effects of two representative voxels (isocenter and peripheral voxel of the tumor) are computed and compared. At microscopic level, the nucleus dose and damage yields vary among all nucleuses within the voxels. Slightly larger percentage of cDSB yield is observed for the peripheral voxel (55.0%) compared to the isocenter one (52.5%). For isocenter voxel, survival fraction increase monotonically at reduced oxygen environment. Under an extreme anoxic condition (0.001%), survival fraction is calculated to be 80% and the hypoxia reduction factor reaches a maximum value of 2.24. In conclusion, with biological-related variations, the proposed multi-scale approach
is more versatile than the existing approaches for evaluating personalized radiobiological effects in
radiotherapy
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