The whole mesh Deformation Model for 2D and 3D image segmentation

In this paper we present a novel approach for image segmentation using Active Nets and Active Volumes. Those solutions are based on the Deformable Models, with slight difference in the method for describing the shapes of interests - instead of using a contour or a surface they represented the segmented objects with a mesh structure, which allows to describe not only the surface of the objects but also to model their interiors. This is obtained by dividing the nodes of the mesh in two categories, namely internal and external ones, which will be responsible for two different tasks. In our new approach we propose to negate this separation and use only one type of nodes. Using that assumption we manage to significantly shorten the time of segmentation while maintaining its quality

Scotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membrane

p53 is a transcription factor that induces growth arrest or apoptosis in response to cellular stress. To identify new p53-inducible proapoptotic genes, we compared, by differential display, the expression of genes in spleen or thymus of normal and p53 nullizygote mice after γ-irradiation of whole animals. We report the identification and characterization of human and mouse Scotin homologues, a novel gene directly transactivated by p53. The Scotin protein is localized to the ER and the nuclear membrane. Scotin can induce apoptosis in a caspase-dependent manner. Inhibition of endogenous Scotin expression increases resistance to p53-dependent apoptosis induced by DNA damage, suggesting that Scotin plays a role in p53-dependent apoptosis. The discovery of Scotin brings to light a role of the ER in p53-dependent apoptosis

Two-band superconductivity in doped SrTiO3_{3} films and interfaces

We investigate the possibility of multi-band superconductivity in SrTiO$_{3}$ films and interfaces using a two-dimensional two-band model. In the undoped compound, one of the bands is occupied whereas the other is empty. As the chemical potential shifts due to doping by negative charge carriers or application of an electric field, the second band becomes occupied, giving rise to a strong enhancement of the transition temperature and a sharp feature in the gap functions, which is manifested in the local density of states spectrum. By comparing our results with tunneling experiments in Nb-doped SrTiO$_{3}$, we find that intra-band pairing dominates over inter-band pairing, unlike other known multi-band superconductors. Given the similarities with the value of the transition temperature and with the band structure of LaAlO$_{3}$/SrTiO$_{3}$ heterostructures, we speculate that the superconductivity observed in SrTiO$_{3}$ interfaces may be similar in nature to that of bulk SrTiO$_{3}$, involving multiple bands with distinct electronic occupations.Comment: revised expanded versio

Modular classes of Poisson-Nijenhuis Lie algebroids

The modular vector field of a Poisson-Nijenhuis Lie algebroid $A$ is defined and we prove that, in case of non-degeneracy, this vector field defines a hierarchy of bi-Hamiltonian $A$-vector fields. This hierarchy covers an integrable hierarchy on the base manifold, which may not have a Poisson-Nijenhuis structure.Comment: To appear in Letters in Mathematical Physic

Seismic strengthening of beam-column joints with multidirectional CFRP laminates

An experimental program was carried out to analyse the potentialities of a technique based on the use of multidirectional CFRP laminates (MDL-CFRP) for the seismic repair and strengthening of reinforced concrete (RC) beam-column joints. This experimental program comprises cyclic tests on three full-scale RC joints, representative of interior beam-column connections in buildings. The joints were initially submitted to a cyclic test inducing a damage pattern representative of a seismic event. Subsequently, they were repaired and strengthened with MDL-CFRP. The strengthened joints were then tested for the same loading history of the original ones up to their failure. The adopted strengthening technique uses the MDL-CFRP that are simultaneously glued and anchored to the concrete surfaces. This technique is called Mechanically Fastened and Externally Bonded Reinforcement (MF-EBR). In the present study, the effectiveness of two different strengthening configurations was investigated. The tests are described and the main results are presented and analyzed