2,593 research outputs found

    An Inconsistency in the Simulation of Bose-Einstein Correlations

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    We show that the formalism commonly used to implement Bose-Einstein correlations in Monte-Carlo simulations can lead to values of the two-particle correlator significantly smaller than unity, in the case of sources with strong position-momentum correlations. This is more pronounced when the phase space of the emitted particles is strongly reduced by experimental acceptance or kinematic analysis selections. It is inconsistent with general principles according to which the Bose-Einstein correlator is larger than unity. This inconsistency seems to be rooted in the fact that quantum mechanical localization properties are not taken into account properly.Comment: 10 pages, LaTe

    The role of mitogen-activated protein kinases and sterol receptor coactivator-1 in TGF-β-regulated expression of genes implicated in macrophage cholesterol uptake

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    The anti-atherogenic cytokine TGF-β inhibits macrophage foam cell formation by suppressing the expression of key genes implicated in the uptake of modified lipoproteins. We have previously shown a critical role for p38 MAPK and JNK in the TGF-β-mediated regulation of apolipoprotein E expression in human monocytes. However, the roles of these two MAPK pathways in the control of expression of key genes involved in the uptake of modified lipoproteins in human macrophages is poorly understood and formed the focus of this study. TGF-β activated both p38 MAPK and JNK, and knockdown of p38 MAPK or c-Jun, a key downstream target of JNK action, demonstrated their requirement in the TGF-β-inhibited expression of several key genes implicated in macrophage lipoprotein uptake. The potential role of c-Jun and specific co-activators in the action of TGF-β was investigated further by studies on the lipoprotein lipase gene. c-Jun did not directly interact with the minimal promoter region containing the TGF-β response elements and a combination of transient transfection and knock down assays revealed an important role for SRC-1. These studies provide novel insights into the mechanisms underlying the TGF-β-mediated inhibition of macrophage gene expression associated with the control of cholesterol homeostasis

    Probabilistic Feasibility for Nonlinear Systems with Non-Gaussian Uncertainty using RRT

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    For motion planning problems involving many or unbounded forms of uncertainty, it may not be possible to identify a path guaranteed to be feasible, requiring consideration of the trade-o between planner conservatism and the risk of infeasibility. Recent work developed the chance constrained rapidly-exploring random tree (CC-RRT) algorithm, a real-time planning algorithm which can e ciently compute risk at each timestep in order to guarantee probabilistic feasibility. However, the results in that paper require the dual assumptions of a linear system and Gaussian uncertainty, two assumptions which are often not applicable to many real-life path planning scenarios. This paper presents several extensions to the CC-RRT framework which allow these assumptions to be relaxed. For nonlinear systems subject to Gaussian process noise, state distributions can be approximated as Gaussian by considering a linearization of the dynamics at each timestep; simulation results demonstrate the e ective of this approach for both open-loop and closed-loop dynamics. For systems subject to non-Gaussian uncertainty, we propose a particle-based representation of the uncertainty, and thus the state distributions; as the number of particles increases, the particles approach the true uncertainty. A key aspect of this approach relative to previous work is the consideration of probabilistic bounds on constraint satisfaction, both at every timestep and over the duration of entire paths.United States. Air Force (USAF, grant FA9550-08-1-0086)United States. Air Force Office of Scientific Research (AFOSR, Grant FA9550-08-1-0086

    Quantum Mechanical Localization Effects for Bose-Einstein Correlations

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    For a set of N identical massive boson wavepackets with optimal initial quantum mechanical localization, we derive the Hanbury-Brown/Twiss (HBT) two-particle correlation function. Our result provides finite multiplicity corrections to the coherent state formalism and allows to trace back an error in the so-called cos-prescription. It suggests that what the HBT radius parameters in very small boson emitting systems (e.g. Z_0-decays, p-pbar annihilation) measure is essentially the initial spatial wavepacket width. Both one- and two-particle spectra depend explicitly on this width. Our derivation gives an algorithm for calculating one-particle spectra and two-particle correlations from an arbitrary phase space occupation (q_i,p_i,t_i) as e.g. returned by event generators of heavy ion collisions

    Search for the QCD critical point in nuclear collisions at the CERN SPS

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    Pion production in nuclear collisions at the SPS is investigated with the aim to search, in a restricted domain of the phase diagram, for power-laws in the behavior of correlations which are compatible with critical QCD. We have analyzed interactions of nuclei of different size (p+p, C+C, Si+Si, Pb+Pb) at 158AA GeV adopting, as appropriate observables, scaled factorial moments in a search for intermittent fluctuations in transverse dimensions. The analysis is performed for π+π\pi^+\pi^- pairs with invariant mass very close to the two-pion threshold. In this sector one may capture critical fluctuations of the sigma component in a hadronic medium, even if the σ\sigma-meson has no well defined vacuum state. It turns out that for the Pb+Pb system the proposed analysis technique cannot be applied without entering the invariant mass region with strong Coulomb correlations. As a result the treatment becomes inconclusive in this case. Our results for the other systems indicate the presence of power-law fluctuations in the freeze-out state of Si+Si approaching in size the prediction of critical QCD.Comment: 31 pages, 11 figure

    Measurement of event-by-event transverse momentum and multiplicity fluctuations using strongly intensive measures Δ[PT,N]\Delta[P_T, N] and Σ[PT,N]\Sigma[P_T, N] in nucleus-nucleus collisions at the CERN Super Proton Synchrotron

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    Results from the NA49 experiment at the CERN SPS are presented on event-by-event transverse momentum and multiplicity fluctuations of charged particles, produced at forward rapidities in central Pb+Pb interactions at beam momenta 20AA, 30AA, 40AA, 80AA, and 158AA GeV/c, as well as in systems of different size (p+pp+p, C+C, Si+Si, and Pb+Pb) at 158AA GeV/c. This publication extends the previous NA49 measurements of the strongly intensive measure ΦpT\Phi_{p_T} by a study of the recently proposed strongly intensive measures of fluctuations Δ[PT,N]\Delta[P_T, N] and Σ[PT,N]\Sigma[P_T, N]. In the explored kinematic region transverse momentum and multiplicity fluctuations show no significant energy dependence in the SPS energy range. However, a remarkable system size dependence is observed for both Δ[PT,N]\Delta[P_T, N] and Σ[PT,N]\Sigma[P_T, N], with the largest values measured in peripheral Pb+Pb interactions. The results are compared with NA61/SHINE measurements in p+pp+p collisions, as well as with predictions of the UrQMD and EPOS models.Comment: 12 pages, 14 figures, to be submitted to PR

    High p_T Spectra of Identified Particles Produced in Pb+Pb Collisions at 158A GeV Beam Energy

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    Results of the NA49 collaboration on the production of hadrons with large transverse momentum in Pb+Pb collisions at 158A GeV beam energy are presented. A range up to p_T = 4 GeV/c is covered. The nuclear modification factor R_CP is extracted for pions, kaons and protons, and the baryon to meson ratios p/pi+, pbar/pi- and Lambda/K^0_s are studied. All results are compared to other measurements at SPS and RHIC and to theoretical calculations.Comment: Submitted to J. Phys. G (Proceedings of the 9th International Conference on Strangeness in Quark Matter, Los Angeles, USA, March 26-31, 2006). 5 pages, 3 figure

    Strangeness production at SPS energies

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    We present a summary of measurements of strange particles performed by the experiment NA49 in central and minimum bias Pb+Pb collisions in the beam energy range 20A - 158A GeV. New results on Xi production in central Pb+Pb collisions and on Lambda, Xi production in minimum bias collisions are shown. Transverse mass spectra and rapidity distributions of strange particles at different energies are compared. The energy dependence of the particle yields and ratios is discussed. NA49 measurements of the Lambda and Xi enhancement factors are shown for the first time.Comment: Submitted to J. Phys. G (Proceedings of the 9th International Conference on Strangeness in Quark Matter, Los Angeles, USA, March 26-31, 2006). 9 pages, 9 figure

    System-size and centrality dependence of charged kaon and pion production in nucleus-nucleus collisions at 40A GeV and158A GeV beam energy

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    Measurements of charged pion and kaon production are presented in centrality selected Pb+Pb collisions at 40A GeV and 158A GeV beam energy as well as in semi-central C+C and Si+Si interactions at 40A GeV. Transverse mass spectra, rapidity spectra and total yields are determined as a function of centrality. The system-size and centrality dependence of relative strangeness production in nucleus-nucleus collisions at 40A GeV and 158A GeV beam energy are derived from the data presented here and published data for C+C and Si+Si collisions at 158A GeV beam energy. At both energies a steep increase with centrality is observed for small systems followed by a weak rise or even saturation for higher centralities. This behavior is compared to calculations using transport models (UrQMD and HSD), a percolation model and the core-corona approach.Comment: 32 pages, 14 figures, 4 tables, typo table II correcte

    Charged Particle Production in Proton-, Deuteron-, Oxygen- and Sulphur-Nucleus Collisions at 200 GeV per Nucleon

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    The transverse momentum and rapidity distributions of net protons and negatively charged hadrons have been measured for minimum bias proton-nucleus and deuteron-gold interactions, as well as central oxygen-gold and sulphur-nucleus collisions at 200 GeV per nucleon. The rapidity density of net protons at midrapidity in central nucleus-nucleus collisions increases both with target mass for sulphur projectiles and with the projectile mass for a gold target. The shape of the rapidity distributions of net protons forward of midrapidity for d+Au and central S+Au collisions is similar. The average rapidity loss is larger than 2 units of rapidity for reactions with the gold target. The transverse momentum spectra of net protons for all reactions can be described by a thermal distribution with `temperatures' between 145 +- 11 MeV (p+S interactions) and 244 +- 43 MeV (central S+Au collisions). The multiplicity of negatively charged hadrons increases with the mass of the colliding system. The shape of the transverse momentum spectra of negatively charged hadrons changes from minimum bias p+p and p+S interactions to p+Au and central nucleus-nucleus collisions. The mean transverse momentum is almost constant in the vicinity of midrapidity and shows little variation with the target and projectile masses. The average number of produced negatively charged hadrons per participant baryon increases slightly from p+p, p+A to central S+S,Ag collisions.Comment: 47 pages, submitted to Z. Phys.
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