17,565 research outputs found

    Uniform generation in trace monoids

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    We consider the problem of random uniform generation of traces (the elements of a free partially commutative monoid) in light of the uniform measure on the boundary at infinity of the associated monoid. We obtain a product decomposition of the uniform measure at infinity if the trace monoid has several irreducible components-a case where other notions such as Parry measures, are not defined. Random generation algorithms are then examined.Comment: Full version of the paper in MFCS 2015 with the same titl

    Anophthalmia including next-generation sequencing-based approaches

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    Name of the disease (synonyms) See Table 1, Column 1-"Name of disease" and Column 2-"Alternative names". OMIM# of the disease See Table 1, Column 3-"OMIM# of the disease". Name of the analysed genes or DNA/chromosome segments and OMIM# of the gene(s) Core genes Name of the disease (synonyms) See Table 1, Column 1ā€”ā€œName of diseaseā€ and Column 2ā€”ā€œAlternative namesā€. OMIM# of the disease See Table 1, Column 3ā€”ā€œOMIM# of the diseaseā€. Name of the analysed genes or DNA/chromosome segments and OMIM# of the gene(s) Core genes (irrespective of being tested by Sanger sequencing or next-generation sequencing): See Table 1, Column 4ā€”ā€œCytogenetic locationā€, Column 5ā€”ā€œAssociated gene(s)ā€ and Column 6ā€”ā€œOMIM# of associated gene(s)ā€. Additional genes (if tested by next-generation sequencing, including Whole exome/genome sequencing and panel sequencing): See Table 2, Column 1ā€”ā€œGeneā€, Column 2ā€”ā€œAlternative namesā€, Column 3ā€”ā€œOMIM# of geneā€ and Column 4ā€”ā€œCytogenetic locationā€. Review of the analytical and clinical validity as well as of the clinical utility of DNA-based testing for mutations in the gene(s) in diagnostic, predictive and prenatal settings, and for risk assessment in relatives

    Immunopathogenesis of canine chronic ulcerative stomatitis.

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    Canine Chronic Ulcerative Stomatitis is a spontaneously occurring inflammatory disease of the oral mucosa. An immune-mediated pathogenesis is suspected though not yet proven. We have recently reported on the clinical and histologic features, and identification of select leukocyte cell populations within the lesion. A clinical and histologic similarity to oral lichen planus of people was proposed. In the present study, these initial observations are extended by examining lesions from 24 dogs with clinical evidence of chronic ulcerative stomatitis. Because dogs with chronic ulcerative stomatitis often have concurrent periodontal disease, we wondered if dental plaque/biofilm may be a common instigator of inflammation in both lesions. We hypothesized that dogs with chronic ulcerative stomatitis would exhibit a spectrum of pathologic changes and phenotype of infiltrating leukocytes that would inform lesion pathogenesis and that these changes would differ from inflammatory phenotypes in periodontitis. Previously we identified chronic ulcerative stomatitis lesions to be rich in FoxP3+ and IL17+ cells. As such, we suspect that these leukocytes play an important role in lesion pathogenesis. The current study confirms the presence of moderate to large numbers of FoxP3+ T cells and IL17+ cells in all ulcerative stomatitis lesions using confocal immunofluorescence. Interestingly, the majority of IL17+ cells were determined to be non-T cells and IL17+ cell frequencies were negatively correlated with severity on the clinical scoring system. Three histologic subtypes of ulcerative stomatitis were determined; lichenoid, deep stomatitis and granulomatous. Periodontitis lesions, like stomatitis lesions, were B cell and plasma cell rich, but otherwise differed from the stomatitis lesions. Direct immunofluorescence results did not support an autoantibody-mediated autoimmune disease process. This investigation contributes to the body of literature regarding leukocyte involvement in canine idiopathic inflammatory disease pathogenesis

    Implementation of a voltage multiplier integrated HID ballast circuit with dimming control for automotive application

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    Author name used in this publication: K. W. E. ChengAuthor name used in this publication: D. H. WangPower Electronics Research Centre, Department of Electrical Engineering2009-2010 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

    General discussion on dimming control method used for discharge lamp

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    Author name used in this publication: P. DongAuthor name used in this publication: K. W. E. ChengAuthor name used in this publication: S. L. HoAuthor name used in this publication: D. H. WangAuthor name used in this publication: K. DingPower Electronics Research CentreRefereed conference paper2006-2007 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe

    Adding control to arbitrary unknown quantum operations

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    While quantum computers promise significant advantages, the complexity of quantum algorithms remains a major technological obstacle. We have developed and demonstrated an architecture-independent technique that simplifies adding control qubits to arbitrary quantum operations-a requirement in many quantum algorithms, simulations and metrology. The technique is independent of how the operation is done, does not require knowledge of what the operation is, and largely separates the problems of how to implement a quantum operation in the laboratory and how to add a control. We demonstrate an entanglement-based version in a photonic system, realizing a range of different two-qubit gates with high fidelity.Comment: 9 pages, 8 figure

    A novel detection method for voltage sags

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    Author name used in this publication: K. W. E. ChengAuthor name used in this publication: X. D. XueAuthor name used in this publication: C. D. XuAuthor name used in this publication: Y. B. CheAuthor name used in this publication: D. H. WangAuthor name used in this publication: P. DongPower Electronics Research CentreRefereed conference paper2006-2007 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe

    Superluminal motion of a relativistic jet in the neutron star merger GW170817

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    The binary neutron star merger GW170817 was accompanied by radiation across the electromagnetic spectrum and localized to the galaxy NGC 4993 at a distance of 41+/-3 Mpc. The radio and X-ray afterglows of GW170817 exhibited delayed onset, a gradual rise in the emission with time as t^0.8, a peak at about 150 days post-merger, followed by a relatively rapid decline. To date, various models have been proposed to explain the afterglow emission, including a choked-jet cocoon and a successful-jet cocoon (a.k.a. structured jet). However, the observational data have remained inconclusive as to whether GW170817 launched a successful relativistic jet. Here we show, through Very Long Baseline Interferometry, that the compact radio source associated with GW170817 exhibits superluminal motion between two epochs at 75 and 230 days post-merger. This measurement breaks the degeneracy between the models and indicates that, while the early-time radio emission was powered by a wider-angle outflow (cocoon), the late-time emission was most likely dominated by an energetic and narrowly-collimated jet, with an opening angle of <5 degrees, and observed from a viewing angle of about 20 degrees. The imaging of a collimated relativistic outflow emerging from GW170817 adds substantial weight to the growing evidence linking binary neutron star mergers and short gamma-ray bursts.Comment: 42 pages, 4 figures (main text), 2 figures (supplementary text), 2 tables. Referee and editor comments incorporate

    Threshold Photoelectron Spectrum of Cyclobutadiene: Comparison with Time-Dependent Wavepacket Simulations

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    The C4H4 isomer cyclobutadiene (CBD) is the prime model for antiaromaticity and thus a molecule of considerable interest in chemistry. Because it is highly reactive, it can only be studied under isolated conditions. Its electronic structure is characterized by a pseudo-Jahnā€“Teller effect in the neutral and a E āŠ— Ī² Jahnā€“Teller effect in the cation. As a result, recording photoelectron spectra as well as describing them theoretically has been challenging. Here we present the photoion mass-selected threshold photoelectron spectrum of cyclobutadiene together with a simulation based on time-dependent wavepacket dynamics that includes vibronic coupling in the ion, taking into account eight vibrational modes in the cation. Excellent agreement between theory and experiment is found, and the ionization energy is revised to 8.06 Ā± 0.02 eV
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