17,565 research outputs found
Uniform generation in trace monoids
We consider the problem of random uniform generation of traces (the elements
of a free partially commutative monoid) in light of the uniform measure on the
boundary at infinity of the associated monoid. We obtain a product
decomposition of the uniform measure at infinity if the trace monoid has
several irreducible components-a case where other notions such as Parry
measures, are not defined. Random generation algorithms are then examined.Comment: Full version of the paper in MFCS 2015 with the same titl
Anophthalmia including next-generation sequencing-based approaches
Name of the disease (synonyms) See Table 1, Column 1-"Name of disease" and Column 2-"Alternative names". OMIM# of the disease See Table 1, Column 3-"OMIM# of the disease". Name of the analysed genes or DNA/chromosome segments and OMIM# of the gene(s) Core genes Name of the disease (synonyms)
See Table 1, Column 1āāName of diseaseā and Column 2āāAlternative namesā.
OMIM# of the disease
See Table 1, Column 3āāOMIM# of the diseaseā.
Name of the analysed genes or DNA/chromosome segments and OMIM# of the gene(s)
Core genes (irrespective of being tested by Sanger sequencing or next-generation sequencing):
See Table 1, Column 4āāCytogenetic locationā, Column 5āāAssociated gene(s)ā and Column 6āāOMIM# of associated gene(s)ā.
Additional genes (if tested by next-generation sequencing, including Whole exome/genome sequencing and panel sequencing):
See Table 2, Column 1āāGeneā, Column 2āāAlternative namesā, Column 3āāOMIM# of geneā and Column 4āāCytogenetic locationā.
Review of the analytical and clinical validity as well as of the clinical utility of DNA-based testing for mutations in the gene(s) in diagnostic, predictive and prenatal settings, and for risk assessment in relatives
Immunopathogenesis of canine chronic ulcerative stomatitis.
Canine Chronic Ulcerative Stomatitis is a spontaneously occurring inflammatory disease of the oral mucosa. An immune-mediated pathogenesis is suspected though not yet proven. We have recently reported on the clinical and histologic features, and identification of select leukocyte cell populations within the lesion. A clinical and histologic similarity to oral lichen planus of people was proposed. In the present study, these initial observations are extended by examining lesions from 24 dogs with clinical evidence of chronic ulcerative stomatitis. Because dogs with chronic ulcerative stomatitis often have concurrent periodontal disease, we wondered if dental plaque/biofilm may be a common instigator of inflammation in both lesions. We hypothesized that dogs with chronic ulcerative stomatitis would exhibit a spectrum of pathologic changes and phenotype of infiltrating leukocytes that would inform lesion pathogenesis and that these changes would differ from inflammatory phenotypes in periodontitis. Previously we identified chronic ulcerative stomatitis lesions to be rich in FoxP3+ and IL17+ cells. As such, we suspect that these leukocytes play an important role in lesion pathogenesis. The current study confirms the presence of moderate to large numbers of FoxP3+ T cells and IL17+ cells in all ulcerative stomatitis lesions using confocal immunofluorescence. Interestingly, the majority of IL17+ cells were determined to be non-T cells and IL17+ cell frequencies were negatively correlated with severity on the clinical scoring system. Three histologic subtypes of ulcerative stomatitis were determined; lichenoid, deep stomatitis and granulomatous. Periodontitis lesions, like stomatitis lesions, were B cell and plasma cell rich, but otherwise differed from the stomatitis lesions. Direct immunofluorescence results did not support an autoantibody-mediated autoimmune disease process. This investigation contributes to the body of literature regarding leukocyte involvement in canine idiopathic inflammatory disease pathogenesis
Implementation of a voltage multiplier integrated HID ballast circuit with dimming control for automotive application
Author name used in this publication: K. W. E. ChengAuthor name used in this publication: D. H. WangPower Electronics Research Centre, Department of Electrical Engineering2009-2010 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe
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Absorptive carbon nanotube electrodes: consequences of optical interference loss in thin film solar cells.
A current bottleneck in the thin film photovoltaic field is the fabrication of low cost electrodes. We demonstrate ultrasonically spray coated multiwalled carbon nanotube (CNT) layers as opaque and absorptive metal-free electrodes deposited at low temperatures and free of post-deposition treatment. The electrodes show sheet resistance as low as 3.4 Ī© ā”(-1), comparable to evaporated metallic contacts deposited in vacuum. Organic photovoltaic devices were optically simulated, showing comparable photocurrent generation between reflective metal and absorptive CNT electrodes for photoactive layer thickness larger than 600 nm when using archetypal poly(3-hexylthiophene) (P3HT)ā:ā(6,6)-phenyl C61-butyric acid methyl ester (PCBM) cells. Fabricated devices clearly show that the absorptive CNT electrodes display comparable performance to solution processed and spray coated Ag nanoparticle devices. Additionally, other candidate absorber materials for thin film photovoltaics were simulated with absorptive contacts, elucidating device design in the absence of optical interference and reflection.This research has received partial funding from the Flemish
Department of Economics, Science and
Innovation. J. G. Tait acknowledges partial funding from the
Natural Sciences and Engineering Research Canada. M. De
Volder acknowledges partial funding from the ERC Starting
grant 337739.This is the author accepted manuscript. The final version is available from the Royal Society of Chemistry via http://dx.doi.org/10.1039/C5NR01119
General discussion on dimming control method used for discharge lamp
Author name used in this publication: P. DongAuthor name used in this publication: K. W. E. ChengAuthor name used in this publication: S. L. HoAuthor name used in this publication: D. H. WangAuthor name used in this publication: K. DingPower Electronics Research CentreRefereed conference paper2006-2007 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe
Adding control to arbitrary unknown quantum operations
While quantum computers promise significant advantages, the complexity of
quantum algorithms remains a major technological obstacle. We have developed
and demonstrated an architecture-independent technique that simplifies adding
control qubits to arbitrary quantum operations-a requirement in many quantum
algorithms, simulations and metrology. The technique is independent of how the
operation is done, does not require knowledge of what the operation is, and
largely separates the problems of how to implement a quantum operation in the
laboratory and how to add a control. We demonstrate an entanglement-based
version in a photonic system, realizing a range of different two-qubit gates
with high fidelity.Comment: 9 pages, 8 figure
A novel detection method for voltage sags
Author name used in this publication: K. W. E. ChengAuthor name used in this publication: X. D. XueAuthor name used in this publication: C. D. XuAuthor name used in this publication: Y. B. CheAuthor name used in this publication: D. H. WangAuthor name used in this publication: P. DongPower Electronics Research CentreRefereed conference paper2006-2007 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe
Superluminal motion of a relativistic jet in the neutron star merger GW170817
The binary neutron star merger GW170817 was accompanied by radiation across
the electromagnetic spectrum and localized to the galaxy NGC 4993 at a distance
of 41+/-3 Mpc. The radio and X-ray afterglows of GW170817 exhibited delayed
onset, a gradual rise in the emission with time as t^0.8, a peak at about 150
days post-merger, followed by a relatively rapid decline. To date, various
models have been proposed to explain the afterglow emission, including a
choked-jet cocoon and a successful-jet cocoon (a.k.a. structured jet). However,
the observational data have remained inconclusive as to whether GW170817
launched a successful relativistic jet. Here we show, through Very Long
Baseline Interferometry, that the compact radio source associated with GW170817
exhibits superluminal motion between two epochs at 75 and 230 days post-merger.
This measurement breaks the degeneracy between the models and indicates that,
while the early-time radio emission was powered by a wider-angle outflow
(cocoon), the late-time emission was most likely dominated by an energetic and
narrowly-collimated jet, with an opening angle of <5 degrees, and observed from
a viewing angle of about 20 degrees. The imaging of a collimated relativistic
outflow emerging from GW170817 adds substantial weight to the growing evidence
linking binary neutron star mergers and short gamma-ray bursts.Comment: 42 pages, 4 figures (main text), 2 figures (supplementary text), 2
tables. Referee and editor comments incorporate
Threshold Photoelectron Spectrum of Cyclobutadiene: Comparison with Time-Dependent Wavepacket Simulations
The C4H4 isomer cyclobutadiene (CBD) is the prime model for antiaromaticity and thus a molecule of considerable interest in chemistry. Because it is highly reactive, it can only be studied under isolated conditions. Its electronic structure is characterized by a pseudo-JahnāTeller effect in the neutral and a E ā Ī² JahnāTeller effect in the cation. As a result, recording photoelectron spectra as well as describing them theoretically has been challenging. Here we present the photoion mass-selected threshold photoelectron spectrum of cyclobutadiene together with a simulation based on time-dependent wavepacket dynamics that includes vibronic coupling in the ion, taking into account eight vibrational modes in the cation. Excellent agreement between theory and experiment is found, and the ionization energy is revised to 8.06 Ā± 0.02 eV
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