Shortened PQ interval in the differential diagnosis of Anderson-Fabry disease: a case report

In this article, we present a case of a patient with a late diagnosis of Fabry disease caused by a pathogenic variant in the GLA gene (p.1287_1288dup), who repeatedly attempted interventional treatment of Wolff-Parkinson-White Syndrome due to characteristic electrocardiographic pattern of ventricular preexcitation and paroxysmal arrhythmias. The proposed pathognomonic signs of the disease will ensure timely diagnosis and the appointment of specific treatment

Nonlinear Waves in Multimode Fibers

International audienc

Ultrasound detection of externally induced microthrombi cloud formation: a theoretical study

A mathematical model for the formation of microaggregates (microthrombi) of fibrin polymers in blood flow is considered. It is assumed that the former are induced by an external source (which may be of inflammatory or tumor nature) located in a tissue near the vessel. In either case, specific agents (e.g. cytokines) are emitted from that pathological site. Such substances permeate through the vessel wall to act as primary activators of blood coagulation. A mathematical criterion to describe the formation of an intravascular microthrombi cloud, which is interpreted as an early indicator of subsequent macroscopic thrombi formation is discussed. Such criteria are compared with available experimental detection tests for microthrombi cloud formation by means of ultrasound techniques. Moreover, a similarity-type relation is proposed that links the location of the unfolding microthrombi cloud and the place at which such primary activator reaches the vessel wall