Polygons vs. clumps of discs: a numerical study of the influence of grain shape on the mechanical behaviour of granular materials

We performed a series of numerical vertical compression tests on assemblies of 2D granular material using a Discrete Element code and studied the results with regard to the grain shape. The samples consist of 5,000 grains made from either 3 overlapping discs (clumps - grains with concavities) or six-edged polygons (convex grains). These two grain type have similar external envelopes, which is a function of a geometrical parameter $\alpha$. In this paper, the numerical procedure applied is briefly presented followed by the description of the granular model used. Observations and mechanical analysis of dense and loose granular assemblies under isotropic loading are made. The mechanical response of our numerical granular samples is studied in the framework of the classical vertical compression test with constant lateral stress (biaxial test). The comparison of macroscopic responses of dense and loose samples with various grain shapes shows that when $\alpha$ is considered a concavity parameter, it is therefore a relevant variable for increasing mechanical performances of dense samples. When $\alpha$ is considered an envelope deviation from perfect sphericity, it can control mechanical performances for large strains. Finally, we present some remarks concerning the kinematics of the deformed samples: while some polygon samples subjected to a vertical compression present large damage zones (any polygon shape), dense samples made of clumps always exhibit thin reflecting shear bands. This paper was written as part of a CEGEO research project www.granuloscience.comComment: This version of the paper doesn't include figures. Visit the journal web site to download the final version of the paper with the figure

Experimental validation of nonextensive scaling law in confined granular media

In this letter, we address the relationship between the statistical fluctuations of grain displacements for a full quasistatic plane shear experiment, and the corresponding anomalous diffusion exponent, $\alpha$. We experimentally validate a particular case of the so-called Tsallis-Bukman scaling law, $\alpha = 2 / (3 - q)$, where $q$ is obtained by fitting the probability density function (PDF) of the measured fluctuations with a $q$-Gaussian distribution, and the diffusion exponent is measured independently during the experiment. Applying an original technique, we are able to evince a transition from an anomalous diffusion regime to a Brownian behavior as a function of the length of the strain-window used to calculate the displacements of grains in experiments. The outstanding conformity of fitting curves to a massive amount of experimental data shows a clear broadening of the fluctuation PDFs as the length of the strain-window decreases, and an increment in the value of the diffusion exponent - anomalous diffusion. Regardless of the size of the strain-window considered in the measurements, we show that the Tsallis-Bukman scaling law remains valid, which is the first experimental verification of this relationship for a classical system at different diffusion regimes. We also note that the spatial correlations show marked similarities to the turbulence in fluids, a promising indication that this type of analysis can be used to explore the origins of the macroscopic friction in confined granular materials.Comment: 8 pages 4 figure

Jamming transition in a two-dimensional open granular pile with rolling resistance

We present a molecular dynamics study of the jamming/unjamming transition in two-dimensional granular piles with open boundaries. The grains are modeled by viscoelastic forces, Coulomb friction and resistance to rolling. Two models for the rolling resistance interaction were assessed: one considers a constant rolling friction coefficient, and the other one a strain dependent coefficient. The piles are grown on a finite size substrate and subsequently discharged through an orifice opened at the center of the substrate. Varying the orifice width and taking the final height of the pile after the discharge as the order parameter, one can devise a transition from a jammed regime (when the grain flux is always clogged by an arch) to a catastrophic regime, in which the pile is completely destroyed by an avalanche as large as the system size. A finite size analysis shows that there is a finite orifice width associated with the threshold for the unjamming transition, no matter the model used for the microscopic interactions. As expected, the value of this threshold width increases when rolling resistance is considered, and it depends on the model used for the rolling friction.Comment: 9 pages, 6 figure

Scale separation in granular packings: stress plateaus and fluctuations

It is demonstrated, by numerical simulations of a 2D assembly of polydisperse disks, that there exists a range (plateau) of coarse graining scales for which the stress tensor field in a granular solid is nearly resolution independent, thereby enabling an `objective' definition of this field. Expectedly, it is not the mere size of the the system but the (related) magnitudes of the gradients that determine the widths of the plateaus. Ensemble averaging (even over `small' ensembles) extends the widths of the plateaus to sub-particle scales. The fluctuations within the ensemble are studied as well. Both the response to homogeneous forcing and to an external compressive localized load (and gravity) are studied. Implications to small solid systems and constitutive relations are briefly discussed.Comment: 4 pages, 4 figures, RevTeX 4, Minor corrections to match the published versio

Low temperature shape relaxation of 2-d islands by edge diffusion

We present a precise microscopic description of the limiting step for low temperature shape relaxation of two dimensional islands in which activated diffusion of particles along the boundary is the only mechanism of transport allowed. In particular, we are able to explain why the system is driven irreversibly towards equilibrium. Based on this description, we present a scheme for calculating the duration of the limiting step at each stage of the relaxation process. Finally, we calculate numerically the total relaxation time as predicted by our results and compare it with simulations of the relaxation process.Comment: 11 pages, 5 figures, to appear in Phys. Rev.

Relaxation kinetics in two-dimensional structures

We have studied the approach to equilibrium of islands and pores in two dimensions. The two-regime scenario observed when islands evolve according to a set of particular rules, namely relaxation by steps at low temperature and smooth at high temperature, is generalized to a wide class of kinetic models and the two kinds of structures. Scaling laws for equilibration times are analytically derived and confirmed by kinetic Monte Carlo simulations.Comment: 6 pages, 7 figures, 1 tabl

Efficiently Clustering Very Large Attributed Graphs

Attributed graphs model real networks by enriching their nodes with attributes accounting for properties. Several techniques have been proposed for partitioning these graphs into clusters that are homogeneous with respect to both semantic attributes and to the structure of the graph. However, time and space complexities of state of the art algorithms limit their scalability to medium-sized graphs. We propose SToC (for Semantic-Topological Clustering), a fast and scalable algorithm for partitioning large attributed graphs. The approach is robust, being compatible both with categorical and with quantitative attributes, and it is tailorable, allowing the user to weight the semantic and topological components. Further, the approach does not require the user to guess in advance the number of clusters. SToC relies on well known approximation techniques such as bottom-k sketches, traditional graph-theoretic concepts, and a new perspective on the composition of heterogeneous distance measures. Experimental results demonstrate its ability to efficiently compute high-quality partitions of large scale attributed graphs.Comment: This work has been published in ASONAM 2017. This version includes an appendix with validation of our attribute model and distance function, omitted in the converence version for lack of space. Please refer to the published versio

Guidelines for initiation of anti-tumour necrosis factor therapy in rheumatoid arthritis: similarities and differences across Europe.

Contains fulltext : 80544.pdf (publisher's version ) (Closed access

Epstein-Barr virus nuclear antigen 3A protein regulates CDKN2B transcription via interaction with MIZ-1

The Epstein-Barr virus (EBV) nuclear antigen 3 family of protein is critical for the EBV-induced primary B-cell growth transformation process. Using a yeast two-hybrid screen we identified 22 novel cellular partners of the EBNA3s. Most importantly, among the newly identified partners, five are known to play direct and important roles in transcriptional regulation. Of these, the Myc-interacting zinc finger protein-1 (MIZ-1) is a transcription factor initially characterized as a binding partner of MYC. MIZ-1 activates the transcription of a number of target genes including the cell cycle inhibitor CDKN2B. Focusing on the EBNA3A/MIZ-1 interaction we demonstrate that binding occurs in EBV-infected cells expressing both proteins at endogenous physiological levels and that in the presence of EBNA3A, a significant fraction of MIZ-1 translocates from the cytoplasm to the nucleus. Moreover, we show that a trimeric complex composed of a MIZ-1 recognition DNA element, MIZ-1 and EBNA3A can be formed, and that interaction of MIZ-1 with nucleophosmin (NPM), one of its coactivator, is prevented by EBNA3A. Finally, we show that, in the presence of EBNA3A, expression of the MIZ-1 target gene, CDKN2B, is downregulated and repressive H3K27 marks are established on its promoter region suggesting that EBNA3A directly counteracts the growth inhibitory action of MIZ-1