A possible origin of superconducting currents in cosmic strings

The scattering and capture of right-handed neutrinos by an Abelian cosmic string in the SO(10) grand unification model are considered. The scattering cross-section of neutrinos per unit length due to the interaction with the gauge and Higgs fields of the string is much larger in its scaling regime than in the friction one because of the larger infrared cutoff of the former.The probability of capture in a zero mode of the string accompanied by the emission of a gauge or Higgs boson shows a resonant peak for neutrino momentum of the order of its mass. Considering the decrease of number of strings per unit comoving volume in the scaling epoch the cosmological consequences of the superconducting strings formed in this regime will be much smaller than those which could be produced already in the friction one.Comment: 14 pages Latex, 4 figues/ep

WIMP Dark Matter and the QCD Equation of State

Weakly Interacting Massive Particles (WIMPs) of mass m freeze out at a temperature T_f ~ m/25, i.e. in the range 400 MeV -- 40 GeV for a particle in the typical mass range 10 -- 1000 GeV. The WIMP relic density, which depends on the effective number of relativistic degrees of freedom at T_f, may be measured to better than 1% by Planck, warranting comparable theoretical precision. Recent theoretical and experimental advances in the understanding of high temperature QCD show that the quark gluon plasma departs significantly from ideal behaviour up to temperatures of several GeV, necessitating an improvement of the cosmological equation of state over those currently used. We discuss how this increases the relic density by approximately 1.5 -- 3.5% in benchmark mSUGRA models, with an uncertainly in the QCD corrections of 0.5 -- 1 %. We point out what further work is required to achieve a theoretical accuracy comparable with the expected observational precision, and speculate that the effective number of degrees of freedom at T_f may become measurable in the foreseeable future.Comment: 4pp, 2figs. More info including Matlab scripts used to generate equation of state curves at http://www.pact.cpes.sussex.ac.uk/arXiv/hep-ph/0501232

Where are the Hedgehogs in Nematics?

In experiments which take a liquid crystal rapidly from the isotropic to the nematic phase, a dense tangle of defects is formed. In nematics, there are in principle both line and point defects (``hedgehogs''), but no point defects are observed until the defect network has coarsened appreciably. In this letter the expected density of point defects is shown to be extremely low, approximately $10^{-8}$ per initially correlated domain, as result of the topology (specifically, the homology) of the order parameter space.Comment: 6 pages, latex, 1 figure (self-unpacking PostScript)

Defect formation and local gauge invariance

We propose a new mechanism for formation of topological defects in a U(1) model with a local gauge symmetry. This mechanism leads to definite predictions, which are qualitatively different from those of the Kibble-Zurek mechanism of global theories. We confirm these predictions in numerical simulations, and they can also be tested in superconductor experiments. We believe that the mechanism generalizes to more complicated theories.Comment: REVTeX, 4 pages, 2 figures. The explicit form of the Hamiltonian and the equations of motion added. To appear in PRL (http://prl.aps.org/

Cosmic Necklaces and Ultrahigh Energy Cosmic Rays

Cosmic necklaces are hybrid topological defects consisting of monopoles and strings, with two strings attached to each monopole. We argue that the cosmological evolution of necklaces may significantly differ from that of cosmic strings. The typical velocity of necklaces can be much smaller than the speed of light, and the characteristic scale of the network much smaller than the horizon. We estimate the flux of high-energy protons produced by monopole annihilation in the decaying closed loops. For some reasonable values of the parameters it is comparable to the observed flux of ultrahigh-energy cosmic rays.Comment: 10 pages, Revtex, 1 figur

Repetitive Stimulation of the Pituitary with Growth-Hormone-Releasing Hormone Alters the Proportion of 22 and 20 Kilodalton Human-Growth Hormone Released

Background/Aims. 20 Kilodalton-hGH (20 K-hGH) is the second most abundant pituitary GH variant after 22 K-hGH. In the steady state the proportion of 20 : 22 K-hGH appears constant; does this proportion change with repetitive somatotroph stimulation? Methods. Forty adult males were randomised to receive a GHRH(1–29)NH2 bolus (0.5 μg/kg (n = 20) or 1.0 μg/kg (n = 20)), preceded or followed by a saline bolus, 1 week apart. Four to six weeks later, 10 subjects received 0.5 μg/kg GHRH(1–29)NH2 at 0, 60, 120, and 180 minutes. Clearance rate of 22 and 20 K-hGH was measured in 10 subjects. Results. Total amount/proportion of 22 K-hGH/20 K-hGH secreted was similar for both GHRH(1–29)NH2 doses. Repetitive stimulation reduced the amount of 22 K-hGH released whereas the amount of 20 K-hGH did not change significantly leading to an increase in the proportion of 20 K-hGH (P = .05). Half-life of 20 and 22 K-hGH were not significantly different (P = .55). Conclusions. Repetitive stimulation of the somatotroph may alter the proportion of GH variant released

Transport of flexible chiral objects in a uniform shear flow

The transport of slightly deformable chiral objects in a uniform shear flow is investigated. Depending on the equilibrium configuration one finds up to four different asymptotic states that can be distinguished by a lateral drift velocity of their center of mass, a rotational motion about the center of mass and deformations of the object. These deformations influence the magnitudes of the principal axes of the second moment tensor of the considered object and also modify a scalar index characterizing its chirality. Moreover, the deformations induced by the shear flow are essential for the phenomenon of dynamical symmetry breaking: Objects that are achiral under equilibrium conditions may dynamically acquire chirality and consequently experience a drift in the lateral direction.Comment: 25 pages, 16 figure

Cosmic String Network Evolution in arbitrary Friedmann-Lemaitre models

We use the velocity-dependent one-scale model by Martins & Shellard to investigate the evolution of a GUT long cosmic string network in arbitrary Friedmann-Lemaitre models. Four representative models are used to show that in general there is no scaling solution. The implications for structure formation are briefly discussed.Comment: 8 pages, 4 postscript figures included, submitted to Phys. Rev.

BPS String Solutions in Non-Abelian Yang-Mills Theories and Confinement

Starting from the bosonic part of N=2 Super QCD with a 'Seiberg-Witten' N=2 breaking mass term, we obtain string BPS conditions for arbitrary semi-simple gauge groups. We show that the vacuum structure is compatible with a symmetry breaking scheme which allows the existence of Z_k-strings and which has Spin(10) -> SU(5) x Z_2 as a particular case. We obtain BPS Z_k-string solutions and show that they satisfy the same first order differential equations as the BPS string for the U(1) case. We also show that the string tension is constant, which may cause a confining potential between monopoles increasing linearly with their distance.Comment: 11 pages, Latex. Minor changes to the text. Final version to appear in Phys. Rev.

Defining the Newborn Blood Spot Screening Reference Interval for TSH: Impact of Ethnicity

CONTEXT: There is variability in the congenital hypothyroidism (CH) newborn screening TSH cutoff across the United Kingdom. OBJECTIVE: To determine the influences of year, gender, and ethnicity on screening variability and examine whether there is an optimal operational TSH cutoff. DESIGN AND SETTING: Single center, retrospective population study using blood spot TSH cards received by the Great Ormond Street Hospital Screening Laboratory between 2006 and 2012. PATIENTS: A total of 824 588 newborn screening blood spot TSH cards. INTERVENTION: Blood spot TSH results were recorded with demographic data including the Ethnic Category Code. MAIN OUTCOME MEASURES: The proportions of samples exceeding different TSH cutoffs, ranked by ethnicity. RESULTS: The proportion of samples exceeding the TSH cutoff increased over time, with the cutoff at 4 mU/L, but not at 6 mU/L. There was a consistent trend with ethnicity, irrespective of cutoff, with the odds ratio of exceeding the TSH cutoff lowest (∼1.0) in White babies, higher in Pakistani and Bangladeshi (>2.0), and highest in Chinese (>3.5). CONCLUSIONS: The blood spot TSH screening data demonstrate a clear ranking according to ethnicity for differences in mean TSH. This suggests that there may be ethnic differences in thyroid physiology. Ethnic diversity within populations needs to be considered when establishing and interpreting screening TSH cutoffs