Flexural behavior of steel fiber reinforced concrete: testing and modelling

In this paper the results of tests performed on specimens and structural elements made of steel fiber reinforced concrete are presented. Fiber content ranged from 0 to 60 kg/m3 of concrete. Using the results of the uniaxial compression tests performed under displacement control condition, a stress strain relationship for fiber concrete in compression was derived. Three point bending tests on notched beams were carried out in order to simulate the post cracking behavior and to evaluate the fracture energy. Based on the constitutive relationships derived from the experiments, a layered model for the analysis of steel fiber reinforced concrete cross sections was developed. The model performance and the benefits of fiber reinforcement on thin slabs reinforced with steel bars were assessed by carrying out tests on slab strips. The main results are presented and discussed

Design Configuration of a Generation Next Main Battle Tank for Future Combat

The future combat scenario will undergo a sea change as compared to the conventional and un-conventional warfare employed by the traditional armies and non-state actors. In such a scenario, the main battle tank which serves as a game changer during these conflicts has to face the dilemma whether its design should be either evolutionary or revolutionary. To determine the basis of selecting the right type of design based on the above, the broad parameters that define the configuration namely number of crew, weight, armament system, survivability, operating range, transportability, tactical mobility, trafficability, intelligence - surveillance - target acquisition - reconnaissance (ISTAR), system modularity and theatre of operation have been considered. Taking these parameters into account, this study evaluates both the evolutionary and revolutionary design configurations for a generation next main battle tank. Finally, from the outcome of this study it is observed that the revolutionary design approach not only fares better compared to the evolutionary approach, but also possess ease of adaptiveness as an universal combat weapon platform

Ocean barrier layers’ effect on tropical cyclone intensification

Improving a tropical cyclone’s forecast and mitigating its destructive potential requires knowledge of various environmental factors that influence the cyclone’s path and intensity. Herein, using a combination of observations and model simulations, we systematically demonstrate that tropical cyclone intensification is significantly affected by salinity-induced barrier layers, which are “quasi-permanent” features in the upper tropical oceans. When tropical cyclones pass over regions with barrier layers, the increased stratification and stability within the layer reduce storm-induced vertical mixing and sea surface temperature cooling. This causes an increase in enthalpy flux from the ocean to the atmosphere and, consequently, an intensification of tropical cyclones. On average, the tropical cyclone intensification rate is nearly 50% higher over regions with barrier layers, compared to regions without. Our finding, which underscores the importance of observing not only the upper-ocean thermal structure but also the salinity structure in deep tropical barrier layer regions, may be a key to more skillful predictions of tropical cyclone intensities through improved ocean state estimates and simulations of barrier layer processes. As the hydrological cycle responds to global warming, any associated changes in the barrier layer distribution must be considered in projecting future tropical cyclone activity

Drug Target Commons : A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions

Knowledge of the full target space of bioactive substances, approved and investigational drugs as well as chemical probes, provides important insights into therapeutic potential and possible adverse effects. The existing compound-target bioactivity data resources are often incomparable due to non-standardized and heterogeneous assay types and variability in endpoint measurements. To extract higher value from the existing and future compound target-profiling data, we implemented an open-data web platform, named Drug Target Commons (DTC), which features tools for crowd-sourced compound-target bioactivity data annotation, standardization, curation, and intra-resource integration. We demonstrate the unique value of DTC with several examples related to both drug discovery and drug repurposing applications and invite researchers to join this community effort to increase the reuse and extension of compound bioactivity data.Peer reviewe