2,981 research outputs found

    Neutrino oscillations in low density medium

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    For the case of small matter effects: V≪Δm2/2EV \ll \Delta m^2/2E, where VV is the matter potential, we develop the perturbation theory using ϵ≡2VE/Δm2\epsilon \equiv 2VE/\Delta m^2 as the expansion parameter. We derive simple and physically transparent formulas for the oscillation probabilities in the lowest order in ϵ\epsilon which are valid for arbitrary density profile. The formulas can be applied for propagation of the solar and supernova neutrinos in matter of the Earth, substantially simplifying numerical calculations. Using these formulas we study sensitivity of the oscillation effects to structures of the density profile situated at different distances from the detector dd. We show that for the mass-to-flavor state transitions, {\it e.g.}, ν2→νe\nu_2 \to \nu_e, the sensitivity is suppressed for remote structures: d>lνE/ΔEd > l_{\nu} E/\Delta E, where lνl_{\nu} is the oscillation length and ΔE/E\Delta E/E is the energy resolution of detector.Comment: discussion simplified, clarifications adde

    The two ways of gauging the Poincare' group

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    A description of how a theory of gravity can be considered as a gauge theory (in the sense of Trautman) of the Poincare' group is given. As a result, it is shown that a gauge theory of this kind is consistent with the Equivalence Principle only if the Lagrangian and the constraints are preserved not only by the gauge transformations but also by an additional family of transformations, called "pseudo-translations". Explicit expressions of pseudo-translations and of their action on gravitational gauge fields are given. They are expected to be useful for geometric interpretations of their analogues in supergravity theories.Comment: 21 page

    Integration of Neuroimaging and Microarray Datasets through Mapping and Model-Theoretic Semantic Decomposition of Unstructured Phenotypes

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    An approach towards heterogeneous neuroscience dataset integration is proposed that uses Natural Language Processing (NLP) and a knowledge-based phenotype organizer system (PhenOS) to link ontology-anchored terms to underlying data from each database, and then maps these terms based on a computable model of disease (SNOMED CT®). The approach was implemented using sample datasets from fMRIDC, GEO, The Whole Brain Atlas and Neuronames, and allowed for complex queries such as “List all disorders with a finding site of brain region X, and then find the semantically related references in all participating databases based on the ontological model of the disease or its anatomical and morphological attributes”. Precision of the NLP-derived coding of the unstructured phenotypes in each dataset was 88% (n = 50), and precision of the semantic mapping between these terms across datasets was 98% (n = 100). To our knowledge, this is the first example of the use of both semantic decomposition of disease relationships and hierarchical information found in ontologies to integrate heterogeneous phenotypes across clinical and molecular datasets

    Super-Poincare' algebras, space-times and supergravities (I)

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    A new formulation of theories of supergravity as theories satisfying a generalized Principle of General Covariance is given. It is a generalization of the superspace formulation of simple 4D-supergravity of Wess and Zumino and it is designed to obtain geometric descriptions for the supergravities that correspond to the super Poincare' algebras of Alekseevsky and Cortes' classification.Comment: 29 pages, v2: minor improvements at the end of Section 5.

    Nuclear Resonance Vibrational Spectroscopy of Iron Sulfur Proteins

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    Nuclear inelastic scattering in conjunction with density functional theory (DFT) calculations has been applied for the identification of vibrational modes of the high-spin ferric and the high-spin ferrous iron-sulfur center of a rubredoxin-type protein from the thermophylic bacterium Pyrococcus abysii

    Regularity of Kobayashi metric

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    We review some recent results on existence and regularity of Monge-Amp\`ere exhaustions on the smoothly bounded strongly pseudoconvex domains, which admit at least one such exhaustion of sufficiently high regularity. A main consequence of our results is the fact that the Kobayashi pseudo-metric k on an appropriare open subset of each of the above domains is actually a smooth Finsler metric. The class of domains to which our result apply is very large. It includes for instance all smoothly bounded strongly pseudoconvex complete circular domains and all their sufficiently small deformations.Comment: 14 pages, 8 figures - The previously announced main result had a gap. In this new version the corrected statement is given. To appear on the volume "Geometric Complex Analysis - Proceedings of KSCV 12 Symposium

    The Mersey Estuary : sediment geochemistry

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    This report describes a study of the geochemistry of the Mersey estuary carried out between April 2000 and December 2002. The study was the first in a new programme of surveys of the geochemistry of major British estuaries aimed at enhancing our knowledge and understanding of the distribution of contaminants in estuarine sediments. The report first summarises the physical setting, historical development, geology, hydrography and bathymetry of the Mersey estuary and its catchment. Details of the sampling and analytical programmes are then given followed by a discussion of the sedimentology and geochemistry. The chemistry of the water column and suspended particulate matter have not been studied, the chief concern being with the geochemistry of the surface and near-surface sediments of the Mersey estuary and an examination of their likely sources and present state of contamination

    Human Immunodeficiency Virus and Hepatitis C Virus Co-infection in Cameroon: Investigation of the Genetic Diversity and Virulent Circulating Strains

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    Background: RNA virus infections represent a significant cause of illness and death in vertebrates. Specifically in humans, RNA viruses are responsible for a wide range of acute, chronic, emerging and re-emerging infections. HIV and HCV rank as some of the most severe RNA viruse infections facing Africa. Methods: To determine genotypes and subtypes of HIV and HCV among co-infected patients in Cameroon, viral RNA was isolated from HIV/HCV co-infected individuals, in Douala, Cameroon. A total of 36 HIV/HCV co-infected isolates (22 from volunteer blood donors and 14 from people living with HIV/AIDS not yet on antiretroviral treatment) were analyzed using molecular biology techniques that involved RT-PCR, gene/TOPO cloning, DNA sequencing, and bioinformatics tools for sequence management and analysis. Epidemiological data were examined as well.Results: Results show that HIV strains isolated belong to the circulating recombinant forms CRF02_AG, whereas HCV isolates from Cameroon belong to genotypes 1, 2, and 4. The corresponding HCV subtypes investigated were 1a, 1b, 1c, 2a, 2c, 2k, and 4a. Subtypes 1a and 1b, most frequently found in developed countries, also circulate in Cameroon. Epidemiologic data show that HIV/HCV co-infected patients are older than HIVmono-infected patients.Conclusions: These results indicate that HIV/HCV co-infection represent a significant threat in Cameroon. There is evidence of genetic diversity of HIV and HCV; virulent hepatitis C virus subtypes 1a and 1b circulate in Cameroon. An epidemiological and molecular database on HIV and HCV is necessary for the development of further intervention in Cameroon as an imperative for monitoring disease progression.Key words: HIV; HCV; Co-infection ; Genotypes ; Virulent
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