Two extremely metal-poor emission-line galaxies in the Sloan Digital Sky Survey

We present spectroscopic observations with the 3.6m ESO telescope of two emission-line galaxies, J2104-0035 and J0113+0052, selected from the Data Release 4 (DR4) of the Sloan Digital Sky Survey (SDSS). From our data we determine the oxygen abundance of these systems to be respectively 12+logO/H = 7.26+/-0.03 and 7.17+/-0.09, making them the two most metal-deficient galaxies found thus far in the SDSS and placing them among the five most metal-deficient emission-line galaxies ever discovered. Their oxygen abundances are close to those of the two most metal-deficient emission-line galaxies known, SBS0335-052W with 12+logO/H = 7.12+/-0.03 and I Zw 18 with 12+logO/H = 7.17+/-0.01.Comment: 5 pages, 3 figures. Accepted for publication in Astronomy and Astrophysic

Capillarity Theory for the Fly-Casting Mechanism

Biomolecular folding and function are often coupled. During molecular recognition events, one of the binding partners may transiently or partially unfold, allowing more rapid access to a binding site. We describe a simple model for this flycasting mechanism based on the capillarity approximation and polymer chain statistics. The model shows that flycasting is most effective when the protein unfolding barrier is small and the part of the chain which extends towards the target is relatively rigid. These features are often seen in known examples of flycasting in protein-DNA binding. Simulations of protein-DNA binding based on well-funneled native-topology models with electrostatic forces confirm the trends of the analytical theory

Structure and play: rethinking regulation in the higher education sector

This paper explores possible tactics for academics working within a context of increasing regulation and constraint. One suggested tactic is to move outside of a creativity-conformity binary. Rather than understanding creativity and conformity as separable, where one is seen as excluding the other, the authors consider the potential of examining the relationships between them. The theme of 'structure and play' illustrates the argument. In the first part of the paper, using various examples from art and design - fields generally associated with creativity - the authors explore the interrelatedness of creativity and conformity. For example, how might design styles, which are generally understood as creative outcomes, constrain creativity and lead to conformity within the design field? Is fashion producing creativity or conformity? Conversely, the ways in which conformity provides the conditions for creativity are also examined. For example, the conformity imposed by the state on artists in the former communist bloc contributed to a thriving underground arts movement which challenged conformity and state regulation. Continuing the theme of 'structure and play', the authors recount a story from an Australian university which foregrounds the ongoing renegotiation of power relations in the academy. This account illustrates how programmatic government in a university, with its aim of regulating conduct, can contribute to unanticipated outcomes. The authors propose that a Foucauldian view of distributed power is useful for academics operating in a context of increasing regulation, as it brings into view sites where power might begin to be renegotiated