1,691 research outputs found

    Follow-up after treatment for head and neck cancer: United Kingdom National Multidisciplinary Guidelines

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    This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. In the absence of high-level evidence base for follow-up practices, the duration and frequency are often at the discretion of local centres. By reviewing the existing literature and collating experience from varying practices across the UK, this paper provides recommendations on the work up and management of lateral skull base cancer based on the existing evidence base for this rare condition

    A note on the Hybrid Soil Moisture Deficit Model v2.0

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    peer-reviewedThe Hybrid Soil Moisture Deficit (HSMD) model has been used for a wide range of applications, including modelling of grassland productivity and utilisation, assessment of agricultural management opportunities such as slurry spreading, predicting nutrient emissions to the environment and risks of pathogen transfer to water. In the decade since its publication, various ad hoc modifications have been developed and the recent publication of the Irish Soil Information System has facilitated improved assessment of the spatial soil moisture dynamics. In this short note, we formally present a new version of the model (HSMD2.0), which includes two new soil drainage classes, as well as an optional module to account for the topographic wetness index at any location. In addition, we present a new Indicative Soil Drainage Map for Ireland, based on the Irish Soil Classification system, developed as part of the Irish Soil Information System

    Trajectory and spacecraft design for a pole-sitter mission

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    This paper provides a detailed mission analysis and systems design of a pole-sitter mission. It considers a spacecraft that is continuously above either the North or South Pole and, as such, can provide real-time, continuous and hemispherical coverage of the polar regions. Two different propulsion strategies are proposed, which result in a near-term pole-sitter mission using solar electric propulsion and a far-term pole-sitter mission where the electric thruster is hybridized with a solar sail. For both propulsion strategies, minimum propellant pole-sitter orbits are designed. Optimal transfers from Earth to the pole-sitter are designed assuming Soyuz and Ariane 5 launch options, and a controller is shown to be able to maintain the trajectory under unexpected conditions such as injection errors. A detailed mass budget analysis allows for a trade-off between mission lifetime and payload mass capacity, and candidate payloads for a range of applications are investigated. It results that a payload of about 100 kg can operate for approximately 4 years with the solar-electric spacecraft, while the hybrid propulsion technology enables extending the missions up to 7 years. Transfers between north and south pole-sitter orbits are also considered to observe either pole when illuminated by the Sun

    Building consumer trust during the productization phase of a new, smart health tech consumer product

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    Abstract. The thesis aims to investigate the role of trust during the New Product Development (NPD) phase of smart health tech products, focusing on the consumer testing phase. The central research question examines the factors related to trust that arise during the productization/NPD process, and how these factors can be incorporated and enhanced during the development of a new smart health tech product. The study seeks to understand the factors influencing trust in smart health tech products, validate these factors in a real-life business setting, and provide recommendations for future research and productization processes. The research employs a two-step methodology, starting with a literature review to identify general and specific trust-building factors and establish a theoretical framework. Following this, empirical research is conducted with WellO2, a Finnish health tech company planning to launch a new smart mouthpiece designed to measure lung and breathing functions. This phase involves real-life testing of the product to validate the identified trust-building factors and uncover any previously unrecognized factors. The most crucial findings of the study are expected to highlight the key trust-building factors that emerge during the consumer testing phase of the NPD process and offer practical recommendations for incorporating these factors into future product development processes for SMEs. The results of this study are intended to be used by companies involved in the development of smart health tech products to enhance trust during the NPD process, leading to successful product adoption and commercialization. While the research is conducted in the context of a specific company and product, the findings and recommendations may have broader applicability and generalizability to other companies and products in the smart health tech sector.Asiakasluottamuksen rakentaminen uusien ja ÀlykkÀiden terveysteknologiatuotteiden tuotteistamisvaiheessa . TiivistelmÀ. TÀmÀ diplomityö pyrkii tutkimaan luottamuksen roolia ÀlykkÀiden terveysteknologiatuotteiden uuden tuotekehityksen (NPD) vaiheessa, keskittyen kuluttajatestausvaiheeseen. Keskeinen tutkimuskysymys tarkastelee tuotteistamis-/NPD-prosessin aikana esiin tulevia luottamukseen liittyviÀ tekijöitÀ ja sitÀ, kuinka nÀitÀ tekijöitÀ voidaan sisÀllyttÀÀ ja vahvistaa uuden Àlyterveysteknologiatuotteen kehityksessÀ. Tutkimus pyrkii ymmÀrtÀmÀÀn tekijöitÀ, jotka vaikuttavat luottamuksen kehittymiseen Àlyterveysteknologiatuotteissa, arvioimaan nÀitÀ tekijöitÀ todellisessa liiketoimintaympÀristössÀ ja antamaan suosituksia tulevalle tutkimukselle ja tuotteistamisprosesseille. Tutkimus alkaa kirjallisuuskatsauksella, joka pyrkii tunnistamaan luottamuksen rakentamiseen liittyviÀ tekijöitÀ ja luomaan tÀten teoreettisen viitekehyksen aiemman kirjallisuuden pohjalta. TÀmÀn jÀlkeen teoreettista viitekehystÀ ja tunnistettuja luottamusta rakentavia tekijöitÀ tutkitaan todellisessa liiketoimintaympÀristössÀ. Case-yrityksenÀ on suomalainen terveysteknologiayritys WellO2, joka suunnittelee uuden tuotteen (Àlysuukappaleen) lanseerausta, jonka tarkoituksena on pystyÀ mittaamaan keuhkojen hengitystoimintoja. Tutkimuksen aikana tuotetta testattiin todellisessa kuluttajatestausympÀristössÀ ja sillÀ pyrittiin validoimaan tunnistetut luottamuksen rakentamisen tekijÀt ja löytÀmÀÀn uusia, vielÀ tuntemattomia tekijöitÀ. Tutkimuksen tÀrkeimmÀt tulokset korostavat avaintekijöitÀ uuden tuotteen luottamuksen rakentamiseen, mitkÀ nousevat esiin NPD-prosessin kuluttajatestausvaiheessa ja tarjoavat kÀytÀnnön suosituksia nÀiden tekijöiden sisÀllyttÀmiseksi tuleviin tuotekehitysprosesseihin PK-yrityksille. TÀmÀn tutkimuksen tulosten on tarkoitus palvella yrityksiÀ, jotka ovat mukana Àlyterveysteknologiatuotteiden kehittÀmisessÀ ja joiden tarkoituksena on parantaa kuluttajien luottamusta tuotteeseen NPD-prosessin aikana, mikÀ helpottaisi tuotteen menestyksekÀstÀ kÀyttÀjÀhyvÀksyntÀÀ ja kaupallistamista. Vaikka tutkimus on tehty yhden yrityksen ja tuotteen kontekstissa, tuloksilla ja suosituksilla voi olla laajempaa kÀyttöÀ ja yleistettÀvyyttÀ myös muille yrityksille ja tuotteille Àlyterveysteknologia-alalla

    A latent class approach:characterizing the willingness to share personal health information in Finland

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    Abstract. BACKGROUND: With the fast advances in technology, the aging populations, and the climate change, the amount of data in our hands has become enormous, and the ways of handling it has become better. There has been large amount of privacy concerns as well due to the fast-growing data that are spread everywhere. This study focuses on health data to find out whether personal characteristics can be associated with the willingness to consent it for secondary purposes. METHODS: A sample data (n=2338) concerning the Finnish populations attitudes towards secondary uses of health data was acquired and analyzed. The questionnaire included 14 questions regarding the willingness to consent data for different purposes. The dimensionality of this issue was reduced with a latent class analysis, and the information was condensed into one latent variable with 5 classes. After that a latent class regression was performed to find out whether the willingness could be explained with the help of other background information. RESULTS: A statistically significant association between the willingness to consent health data and the following characteristics; Gender, Age, Education, Perception of health, Number of visits to health or social care, and Financial situation. Political orientation had a high value of estimate, but no significance. CONCLUSIONS: Secondary uses of health data can achieve improvements in public health and welfare and health equality. Therefore, it is important that we make sure that the privacy concerns of using and sharing health data are taken care of. Methods for increasing the citizens willingness to consent their health data could be done through education and by building mutual trust between the health care system and the patients

    Mechanical Systems with Symmetry, Variational Principles, and Integration Algorithms

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    This paper studies variational principles for mechanical systems with symmetry and their applications to integration algorithms. We recall some general features of how to reduce variational principles in the presence of a symmetry group along with general features of integration algorithms for mechanical systems. Then we describe some integration algorithms based directly on variational principles using a discretization technique of Veselov. The general idea for these variational integrators is to directly discretize Hamilton’s principle rather than the equations of motion in a way that preserves the original systems invariants, notably the symplectic form and, via a discrete version of Noether’s theorem, the momentum map. The resulting mechanical integrators are second-order accurate, implicit, symplectic-momentum algorithms. We apply these integrators to the rigid body and the double spherical pendulum to show that the techniques are competitive with existing integrators

    Unstable recurrent patterns in Kuramoto-Sivashinsky dynamics

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    We undertake a systematic exploration of recurrent patterns in a 1-dimensional Kuramoto-Sivashinsky system. For a small, but already rather turbulent system, the long-time dynamics takes place on a low-dimensional invariant manifold. A set of equilibria offers a coarse geometrical partition of this manifold. A variational method enables us to determine numerically a large number of unstable spatiotemporally periodic solutions. The attracting set appears surprisingly thin - its backbone are several Smale horseshoe repellers, well approximated by intrinsic local 1-dimensional return maps, each with an approximate symbolic dynamics. The dynamics appears decomposable into chaotic dynamics within such local repellers, interspersed by rapid jumps between them.Comment: 11 pages, 11 figure

    Formulation and performance of variational integrators for rotating bodies

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    Variational integrators are obtained for two mechanical systems whose configuration spaces are, respectively, the rotation group and the unit sphere. In the first case, an integration algorithm is presented for Euler’s equations of the free rigid body, following the ideas of Marsden et al. (Nonlinearity 12:1647–1662, 1999). In the second example, a variational time integrator is formulated for the rigid dumbbell. Both methods are formulated directly on their nonlinear configuration spaces, without using Lagrange multipliers. They are one-step, second order methods which show exact conservation of a discrete angular momentum which is identified in each case. Numerical examples illustrate their properties and compare them with existing integrators of the literature

    Education of trainees, training and fellowships for head and neck oncologic and surgical training in the UK:United Kingdom National Multidisciplinary Guidelines

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    Since the previous edition of these guidelines, significant changes have taken place in the training and assessment of surgeons and oncologists who treat patients with head and neck cancer. For those intending to become head and neck surgeons, a fellowship in head and neck surgery is virtually mandatory. This paper summarises the current career structure to specialise in head and neck oncology and surgery in the UK. RECOMMENDATION: ‱ Trainees applying for head and neck surgical oncology consultant posts should have completed additional training in the subspecialty
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