Carbon in soils

Carbon is the fourth most common element in the galaxy(by mass) but does not even rank in the twelve most abundant elements on Earth. By far the most abundant source of carbon on Earth is in the crust as inorganic rocks such as calcite and limestone in marine and sedimentary deposits. These rocks have taken many millions of years to form. Other major inorganic sources are in the oceans and atmosphere

Nitrogen, soils and environment

The article discusses the risk of damaging the environment brought by nitrogen fertilisers which are used for increasing agricultural productivity. The oxidation of ammonium allows for the formation of nitrate. Troposphere ozone and aerosols are produced through the increase of reactive nitrogen in the atmosphere

Adiabatic connection at negative coupling strengths

The adiabatic connection of density functional theory (DFT) for electronic systems is generalized here to negative values of the coupling strength $\alpha$ (with {\em attractive} electrons). In the extreme limit $\alpha\to-\infty$ a simple physical solution is presented and its implications for DFT (as well as its limitations) are discussed. For two-electron systems (a case in which the present solution can be calculated exactly), we find that an interpolation between the limit $\alpha\to-\infty$ and the opposite limit of infinitely strong repulsion ($\alpha\to+\infty$) yields a rather accurate estimate of the second-order correlation energy E\cor\glt[\rho] for several different densities $\rho$, without using virtual orbitals. The same procedure is also applied to the Be isoelectronic series, analyzing the effects of near-degeneracy.Comment: 9 pages, submitted to PR

Multiple small monthly doses of dicyandiamide (DCD) did not reduce denitrification in Waikato dairy pasture

The effectiveness of multiple small doses of the nitrification inhibitor dicyandiamide (DCD) to decrease denitrification under warm moist conditions was tested in a 1-year field trial on a grazed dairy pasture. DCD was applied approximately every 4 weeks as an aqueous spray onto ten replicate plots 3 days after rotational grazing by dairy cows. Each application was at the rate of 3 kg DCD ha⁻¹, with a total annual application of 33 kg ha⁻¹. Denitrification was assessed 5 days after each DCD application using the acetylene block method. At the end of the trial, the rate of degradation of DCD under summer conditions was measured. DCD significantly decreased the mean annual nitrate concentration by about 17%. Denitrification and denitrification enzyme activity were highly variable and no significant effect of DCD in decreasing denitrification was detected. In the summer month of December, DCD degraded rapidly with an estimated half-life of 5 ± 3 days (mean and standard deviation)

Towards controlled microneedle-mediated intradermal immunization

Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye. Microneedles may administer vaccine into the skin in a pain-free manner. By using the intradermal route for immunization, a high number of immune cells in the skin are targeted, which may result in more efficient immunization. In this thesis, several aspects of intradermal immunization were investigated by using hollow microneedles. As differently specialized immune cells reside at different depths in skin, immunization outcomes as function of injection depth in skin were investigated to determine effects of injection depth. Furthermore, as prolonged antigen exposure may enhance immune responses, immunization outcomes resulting from repeated fractional intradermal dosing schedules were compared to those resulting from bolus dosing schedules. Finally, a layer-by-layer coating approach was developed for solid microneedle arrays. In the layer-by-layer coating approach, alternating layers of antigen and polymer are coated onto the surface of microneedle arrays. This approach enabled coating and intradermal delivery of a precise amount of antigen. Intradermal immunization using layer-by-layer coated microneedle arrays resulted in effective immunization. In conclusion, these studies provide important insights towards controlled microneedle-mediated intradermal immunization.This study was funded by the Dutch Technology Foundation STW, which is part of the Netherlands Organization for Scientific Research (NWO), and which is partly funded by the Ministry of Economic Affairs (project no. 11259).Drug Delivery Technolog

Clinical DRUJ instability does not influence the long-term functional outcome of conservatively treated distal radius fractures

Trauma Surger

Duurzaam beheer volgens SBB

De moeite die terreinbeherende organisaties hebben om de achteruitgang van de biodiversiteit in Nederland te stoppen heeft te maken met de verstoring van landschapsecologische processen. Het herstel daarvan is de sleutel tot de instandhouding van natuurwaarden. Op basis van dat uitgangspunt heeft Staatsbosbeheer een afwegingskader voor een duurzaam natuurbeheer in de toekomst ontwikkeld. met dit kader wil de organisatie een bijdrage leveren aan de discussie over de herijking van de EH