929 research outputs found

    Propuesta de dise?o curricular para el ?rea de m?sica en la escuela de formaci?n art?stica y musical "EFAM" del municipio de Venadillo - Tolima

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    54 p. Recurso Electr?nicoEl presente trabajo de grado ?Propuesta de dise?o curricular para el ?rea de m?sica en la escuela de formaci?n art?stica y musical EFAM del municipio de Venadillo ? Tolima? tiene como prop?sito fundamental, la identificaci?n de las principales fortalezas de una escuela que ha funcionado durante dos a?os en la zona c?ntrica del municipio de Venadillo - Tolima, en las antiguas instalaciones de la c?rcel municipal, y que se ha convertido en el sitio de formaci?n inicial musical por excelencia entre los ni?os, j?venes y adultos que componen la zona norte del Departamento. Empero, entre sus muchos beneficios, la escuela carece de una propuesta curricular estructurada que les ha impedido a los estudiantes certificar los conocimientos adquiridos en la escuela de m?sica. Por ello, se hace una caracterizaci?n de su poblaci?n estudiantil, los recursos f?sicos y de talento humano, los requerimientos de formaci?n laboral de los estudiantes para de esta manera comenzar con el desarrollo de la propuesta curricular. Finalmente, dicha propuesta de dise?o curricular se socializa con toda la comunidad educativa para que estos aporten elementos al dise?o curricular e igualmente se les presenta como herramienta opcional, la implementaci?n de un proyecto educativo institucional PEI, para que la Escuela de Formaci?n, pase de ser una instituci?n no formal a un Instituto para el trabajo y el desarrollo humano con licencia de funcionamiento y registro del programa ante la secretaria de educaci?n municipal. Para el desarrollo de este proyecto de grado, se conto con el apoyo de profesionales en el ?rea de dise?o curricular, gesti?n educativa, dise?o de proyectos institucional, evaluaci?n institucional, profesionales en m?sica, psicolog?a y pedagog?a que enriquecieron enormemente el contenido del presente documento.This degree work "Proposed curriculum for the area of music in the school of artistic and musical training EFAM Venadillo Township - Tolima" fundamental purpose, identifying the main strengths of a school that has worked for two years in the central zone of Venadillo - Tolima, in the former premises of the municipal prison, and that has become the site of musical initial training for excellence among children, youth and adults that make up the northern department. However, among its many benefits, the school lacks a structured curriculum proposal that prevented students to certify the knowledge acquired in the school of music. Therefore, a characterization of its student population becomes, the physical and human talent resources, job training requirements of students in this way to start with the development of the proposed curriculum. Finally, this proposed curriculum is socialized with the entire educational community to bring these elements to the curriculum and also are presented as an optional tool, the implementation of an education project PEI, for the School of Education, through being an institution is not formally an Institute for work and human development with operating license and registration program to the municipal education secretary. For the development of this project grade, he had the support of professionals in the area of professional music, psychology and pedagogy that greatly enriched the contents of this document curriculum design, educational management, design of institutional projects, institutional evaluation. Keywords: music, curriculum, educational project, education for work

    Long-Term Influence of the Practice of Physical Activity on the Self-Perceived Quality of Life of Women with Breast Cancer: A Randomized Controlled Trial.

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    Background: There is still no consensus on the most suitable interventions for exercise practice in breast cancer survivors. Therefore, the aim of this study was to evaluate the effect of a two-year physical activity intervention (strength, aqua fitness and aerobic exercise programs) on the self-perceived quality of life and physical functionality of female breast cancer survivors. Methods: A randomized, controlled, experimental trial with a sample of 316 women (63 +/- 7 years), who had been diagnosed with breast cancer. The evaluations were performed using the Rikli & Jones Senior Fitness Test, and the Short Form 12 Health Survey (SF-12). Results: The participants in the strength program showed statistically significant improvements in all the items of the SF-12. The aqua fitness program obtained significant improvements in Physical Functioning and Limitations, Pain and Emotional Limitations, General Health, Vitality, Social Functioning and the physical and mental components of the SF-12. The participants in the aerobic program showed a progressive deterioration of Vitality and Mental Health. Conclusion: When assigning breast cancer survivors to an exercise program, the preferential or predominant activity should include strength exercises. On the other hand, as the second choice, those patients with particularly low levels of Vitality or Physical Limitations will show greater improvement with an aqua fitness program

    Propuesta de dise?o curricular para el ?rea de m?sica en la escuela de formaci?n art?stitca y musical ?UFAM? del municipio de Venadillo

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    54 P?ginasRecurso Electr?nicoEl presente trabajo de grado ?Propuesta de dise?o curricular para el ?rea de m?sica en la escuela de formaci?n art?stica y musical EFAM del municipio de Venadillo ? Tolima? tiene como prop?sito fundamental, la identificaci?n de las principales fortalezas de una escuela que ha funcionado durante dos a?os en la zona c?ntrica del municipio de Venadillo - Tolima, en las antiguas instalaciones de la c?rcel municipal, y que se ha convertido en el sitio de formaci?n inicial musical por excelencia entre los ni?os, j?venes y adultos que componen la zona norte del Departamento. Empero, entre sus muchos beneficios, la escuela carece de una propuesta curricular estructurada que les ha impedido a los estudiantes certificar los conocimientos adquiridos en la escuela de m?sica. Por ello, se hace una caracterizaci?n de su poblaci?n estudiantil, los recursos f?sicos y de talento humano, los requerimientos de formaci?n laboral de los estudiantes para de esta manera comenzar con el desarrollo de la propuesta curricular. Finalmente, dicha propuesta de dise?o curricular se socializa con toda la comunidad educativa para que estos aporten elementos al dise?o curricular e igualmente se les presenta como herramienta opcional, la implementaci?n de un proyecto educativo institucional PEI, para que la Escuela de Formaci?n, pase de ser una instituci?n no formal a un Instituto para el trabajo y el desarrollo humano con licencia de funcionamiento y registro del programa ante la secretaria de educaci?n municipal. Para el desarrollo de este proyecto de grado, se conto con el apoyo de profesionales en el ?rea de dise?o curricular, gesti?n educativa, dise?o de proyectos institucional, evaluaci?n institucional, profesionales en m?sica, psicolog?a y pedagog?a que enriquecieron enormemente el contenido del presente documento.ABSTRACT. This degree work "Proposed curriculum for the area of music in the school of artistic and musical training EFAM Venadillo Township - Tolima" fundamental purpose, identifying the main strengths of a school that has worked for two years in the central zone of Venadillo - Tolima, in the former premises of the municipal prison, and that has become the site of musical initial training for excellence among children, youth and adults that make up the northern department. However, among its many benefits, the school lacks a structured curriculum proposal that prevented students to certify the knowledge acquired in the school of music. Therefore, a characterization of its student population becomes, the physical and human talent resources, job training requirements of students in this way to start with the development of the proposed curriculum. Finally, this proposed curriculum is socialized with the entire educational community to bring these elements to the curriculum and also are presented as an optional tool, the implementation of an education project PEI, for the School of Education, through being an institution is not formally an Institute for work and human development with operating license and registration program to the municipal education secretary. For the development of this project grade, he had the support of professionals in the area of professional music, psychology and pedagogy that greatly enriched the contents of this document curriculum design, educational management, design of institutional projects, institutional evaluation.INTRODUCCION 11 1. OBJETIVOS 12 2. JUSTIFICACION 13 3. PROBLEMATIZACION 14 4. PREGUNTA PROBLEMA 16 5. MARCO REFERENCIAL 17 5.1 MARCO TEORICO 17 6. METODOLOGIA 19 6.1 HERRAMIENTAS 19 7. ANALISIS DE LOS RESULTADOS 20 8. CONCLUSIONES 47 RECOMENDACIONES 48 REFERENCIAS 49 ANEXOS 5

    Recomendaciones nacionales sobre donaci?n pedi?trica

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    Despite being an international reference in donation and transplantation, Spain needs to improve pediatric donation, including donation after the circulatory determination of death. The present article, a summary of the consensus report prepared by the Organizacion Nacional de Trasplantes and the Spanish Pediatrics Association, intends the facilitation of donation procedures in newborns and children and the analysis of associated ethical dilemma. The ethical basis for donation in children, the principles of clinical assessment of possible donors, the criteria for the determination of death in children, intensive care management of donors, basic concepts of donation after the circulatory determination of death and the procedures for donation in newborns with severe nervous system's malformation incompatible with life, as well as in children receiving palliative care are commented. Systematically considering the donation of organs and tissues when a child dies in conditions consistent with donation is an ethical imperative and must become an ethical standard, not only because of the need of organs for transplantation, but also to ensure family centered care.A pesar de ser una referencia internacional en donaci?n y trasplante, Espa?a precisa mejorar los procesos de donaci?n en ni?os, en particular la donaci?n tras la determinaci?n de la muerte por criterios circulatorios (donaci?n en asistolia). El presente art?culo, resumen del documento de consenso elaborado por la Organizaci?n Nacional de Trasplantes y la Asociaci?n Espa?ola de Pediatr?a, pretende facilitar los procesos de donaci?n en ni?os y neonatos y analizar los conflictos ?ticos que plantea. Se comentan los fundamentos ?ticos de la donaci?n pedi?trica, los principios de la evaluaci?n cl?nica de los posibles donantes, los criterios diagn?sticos de muerte encef?lica en ni?os, los cuidados intensivos para el mantenimiento de los donantes, los conceptos b?sicos de la donaci?n en asistolia y los procesos de donaci?n en neonatos con malformaciones muy graves del sistema nervioso incompatibles con la vida y en ni?os en cuidados paliativos. Considerar sistem?ticamente la donaci?n de ?rganos y tejidos cuando un ni?o fallece en condiciones de ser donante es un imperativo ?tico y ha de constituir un est?ndar profesional, tanto por la necesidad de ?rganos para trasplante, como por asegurar un cuidado integral centrado en la familia

    Kesterite thin films of Cu2ZnSnS4 obtained by spray pyrolysis

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    Thin films of Cu2ZnSnS4 CZTS were deposited using the spray pyrolysis method as relatively fast and vacuum free method. Obtained samples were analyzed using the X Ray Fluorescence, grazing incidence X Ray Diffraction and Raman Spectroscopy techniques. Analysis showed close to stoichiometry composition of the films with kesterite type structure but poor crystalline quality and possible existence of secondary phases. To improve the quality of the films, the as prepared layers were annealed in the presence of elemental Sn and S. Comparison of the results before and after annealing showed a strong improvement of the crystalline quality and a significant reduction of concentration of secondary phases of the films without significant change of composition. The measured optical band gap is equal to 1.52 and 1.55 eV in the as prepared and annealed films, respectively. The optical absorption coefficient is found to be gt; 10 4 cm

    New Recurrent Structural Aberrations in the Genome of Chronic Lymphocytic Leukemia Based on Exome-Sequencing Data

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    Chronic lymphocytic leukemia (CLL) is the most frequent lymphoproliferative syndrome in Western countries, and it is characterized by recurrent large genomic rearrangements. During the last decades, array techniques have expanded our knowledge about CLL's karyotypic aberrations. The advent of large sequencing databases expanded our knowledge cancer genomics to an unprecedented resolution and enabled the detection of small-scale structural aberrations in the cancer genome. In this study, we have performed exome-sequencing-based copy number aberration (CNA) and loss of heterozygosity (LOH) analysis in order to detect new recurrent structural aberrations. We describe 54 recurrent focal CNAs enriched in cancer-related pathways, and their association with gene expression and clinical evolution. Furthermore, we discovered recurrent large copy number neutral LOH events affecting key driver genes, and we recapitulate most of the large CNAs that characterize the CLL genome. These results provide "proof-of-concept" evidence supporting the existence of new genes involved in the pathogenesis of CLL

    Influence of Sex on Stroke Prognosis: A Demographic, Clinical, and Molecular Analysis

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    Identifying the complexities of the effect of sex on stroke risk, etiology, and lesion progression may lead to advances in the treatment and care of ischemic stroke (IS) and non-traumatic intracerebral hemorrhage patients (ICH). We studied the sex-related discrepancies on the clinical course of patients with IS and ICH, and we also evaluated possible molecular mechanisms involved. The study's main variable was the patient's functional outcome at 3-months. Logistic regression models were used in order to study the influence of sex on different inflammatory, endothelial and atrial dysfunction markers. We recruited 5,021 patients; 4,060 IS (54.8% male, 45.2% female) and 961 ICH (57.1% male, 42.9% female). Women were on average 5.7 years older than men (6.4 years in IS, 5.1 years in ICH), and more likely to have previous poor functional status, to suffer atrial fibrillation and to be on anticoagulants. IS patients showed sex-related differences at 3-months regarding poorer outcome (55.6% women, 43.6% men, p < 0.0001), but this relationship was not found in ICH (56.8% vs. 61.9%, p = 0.127). In IS, women had higher levels of NT-proBNP and 3-months worse outcome in both cardioembolic and non-cardioembolic stroke patients. Stroke patients showed sex-related differences in pre-hospital data, clinical variables and molecular markers, but only IS patients presented independent sex-related differences in 3-months poor outcome and mortality. There was a relationship between the molecular marker of atrial dysfunction NT-proBNP and worse functional outcome in women, resulting in a possible indicator of increased dysfunction

    Regulatory T cells participate in the recovery of ischemic stroke patients

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    BACKGROUND: Recent preclinical studies have shown that regulatory T cells (Treg) play a key role in the immune response after ischemic stroke (IS). However, the role of Treg in human acute IS has been poorly investigated. Our aim was to study the relationship between circulating Treg and outcome in human IS patients. METHODS: A total of 204 IS patients and 22 control subjects were recruited. The main study variable was good functional outcome at 3 months (modified Rankin scale </=2) considering infarct volume, Early Neurological Deterioration (END) and risk of infections as secondary variables. The percentage of circulating Treg was measured at admission, 48, 72 h and at day 7 after stroke onset. RESULTS: Circulating Treg levels were higher in IS patients compared to control subjects. Treg at 48 h were independently associated with good functional outcome (OR, 3.5; CI: 1.9-7.8) after adjusting by confounding factors. Patients with lower Treg at 48 h showed higher frequency of END and risk of infections. In addition, a negative correlation was found between circulating Treg at 48 h (r = - 0.414) and 72 h (r = - 0.418) and infarct volume. CONCLUSIONS: These findings suggest that Treg may participate in the recovery of IS patients. Therefore, Treg may be considered a potential therapeutic target in acute ischemic stroke

    Antihyperthermic treatment decreases perihematomal hypodensity

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    OBJECTIVE: To investigate the effect on perihematomal hypodensity and outcome of a decrease in body temperature in the first 24 hours in patients with intracerebral hemorrhage (ICH). METHODS: In this retrospective study on a prospectively registered database, among the 1,100 patients, 795 met all the inclusion criteria. Temperature variations in the first 24 hours and perihematomal hypodensity (PHHD) were recorded. Patients >/=37.5 degrees C were treated with antihyperthermic drugs for at least 48 hours. The main objective was to determine the association among temperature variation, PHHD, and outcome at 3 months. RESULTS: The decrease in temperature in the first 24 hours increased the possibility of good outcome 11-fold. Temperature decrease, lower PHHD volume, and a good outcome were observed in 31.8% of the patients who received antihyperthermic treatment. CONCLUSION: The administration of early antihyperthermic treatment in patients with spontaneous ICH with a basal axillary temperature >/=37.5 degrees C resulted in good outcome in a third of the treated patients

    Intra- and extra-hospital improvement in ischemic stroke patients: influence of reperfusion therapy and molecular mechanisms

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    Neuroprotective treatments in ischemic stroke are focused to reduce the pernicious effect of excitotoxicity, oxidative stress and inflammation. However, those cellular and molecular mechanisms may also have beneficial effects, especially during the late stages of the ischemic stroke. The objective of this study was to investigate the relationship between the clinical improvement of ischemic stroke patients and the time-dependent excitotoxicity and inflammation. We included 4295 ischemic stroke patients in a retrospective study. The main outcomes were intra and extra-hospital improvement. High glutamate and IL-6 levels at 24 hours were associated with a worse intra-hospital improvement (OR:0.993, 95%CI: 0.990-0.996 and OR:0.990, 95%CI: 0.985-0.995). High glutamate and IL-6 levels at 24 hours were associated with better extra-hospital improvement (OR:1.13 95%CI, 1.07-1.12 and OR:1.14, 95%CI, 1.09-1.18). Effective reperfusion after recanalization showed the best clinical outcome. However, the long term recovery is less marked in patients with an effective reperfusion. The variations of glutamate and IL6 levels in the first 24 hours clearly showed a relationship between the molecular components of the ischemic cascade and the clinical outcome of patients. Our findings suggest that the rapid reperfusion after recanalization treatment blocks the molecular response to ischemia that is associated with restorative processes
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