129 research outputs found

    Sharp lines in the absorption edge of EuTe and Pb0.1_{0.1}Eu0.9_{0.9}Te in high magnetic fields

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    The optical absorption spectra in the region of the \fd transition energies of epitaxial layers of of EuTe and \PbEuTe, grown by molecular beam epitaxy, were studied using circularly polarized light, in the Faraday configuration. Under \sigmam polarization a sharp symmetric absorption line (full width at half-maximum 0.041 eV) emerges at the low energy side of the band-edge absorption, for magnetic fields intensities greater than 6 T. The absorption line shows a huge red shift (35 meV/T) with increasing magnetic fields. The peak position of the absorption line as a function of magnetic field is dominated by the {\em d-f} exchange interaction of the excited electron and the \Euion spins in the lattice. The {\em d-f} exchange interaction energy was estimated to be JdfS=0.15±0.01J_{df}S=0.15\pm 0.01 eV. In \PbEuTe the same absorption line is detected, but it is broader, due to alloy disorder, indicating that the excitation is localized within a finite radius. From a comparison of the absorption spectra in EuTe and \PbEuTe the characteristic radius of the excitation is estimated to be 10\sim 10\AA.Comment: Journal of Physics: Condensed Matter (2004, at press

    Giant Effective G -factor In Pbx Eu1-x Te Epitaxial Films

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    We investigated Pbx Eu1-x Te films with x≤0.2 by magneto-optical measurements. For x∼0.01, the optical emission is similar to high quality EuTe films with two narrow lines attributed to excitonic recombinations associated with magnetic polarons. For increasing x, the emission becomes dominated by a broader lower energy band, which is very efficient as compared to the binary emission. The magneto-optical properties of the ternary films show various similarities with EuTe results, such as quenchings at similar temperatures and magnetic fields. Most remarkably, they also present a giant effective g -factor that makes this material a strong candidate for spintronic applications. © 2008 American Institute of Physics.933Mauger, A., Godart, C., (1986) Phys. Rep., 141, p. 51Masset, F., (1971) Phys. Rev. B, 3, p. 2364Akimoto, R., Kobayashi, M., Suzuki, T., (1994) J. Phys. Soc. Jpn., 63, p. 4616Heiss, W., Kirchschlager, R., Springholz, G., Chen, Z., Debnath, M., Oka, Y., (2004) Phys. Rev. B, 70, p. 035209Heiss, W., Prechtl, G., Springholz, G., (2001) Phys. Rev. B, 63, p. 165323Heiss, W., Prechtl, G., Springholz, G., (2001) Appl. Phys. Lett., 78, p. 3484Krenn, H., Herbst, W., Pascher, H., Ueta, Y., Springholz, G., Bauer, G., (1999) Phys. Rev. B, 60, p. 8117Springholz, G., Schwarzi, T., Aigle, M., Pascher, H., Heiss, W., (2000) Appl. Phys. Lett., 76, p. 1807Nolting, W., Mathi Jaya, S., Rex, S., (1996) Phys. Rev. B, 54, p. 14455Umehara, M., (2003) Phys. Rev. B, 68, p. 19320

    Magnetic ordering of EuTe/PbTe multilayers determined by x-ray resonant diffraction

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    In this work we use resonant x-ray diffraction combined with polarization analysis of the diffracted beam to study the magnetic ordering in EuTe/PbTe multilayers. The presence of satellites at the (1/2 1/2 1/2) magnetic reflection of a 50 /repetition EuTe/PbTe superlattice demonstrated the existence of magnetic correlations among the alternated EuTe layers. The behavior of the satellites intensity as T increases toward the Neel temperature T(N) indicates that these correlations persist nearly up to T(N) and suggests the preferential decrease of the magnetic order parameter of external monolayers of each EuTe layer within the superlattice. (C) 2008 American Institute of Physics.922

    Characterization and evolution of cell division and cell wall synthesis genes in the bacterial phyla Verrucomicrobia, Lentisphaerae, Chlamydiae and Planctomycetes and phylogenetic comparison with rRNA genes

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    In the past, studies on the relationships of the bacterial phyla Planctomycetes, Chlamydiae, Lentisphaerae, and Verrucomicrobia using different phylogenetic markers have been controversial. Investigations based on 16S rRNA sequence analyses suggested a relationship of the four phyla, showing the branching order Planctomycetes, Chlamydiae, Verrucomicrobia/Lentisphaerae. Phylogenetic analyses of 23S rRNA genes in this study also support a monophyletic grouping and their branching order—this grouping is significant for understanding cell division, since the major bacterial cell division protein FtsZ is absent from members of two of the phyla Chlamydiae and Planctomycetes. In Verrucomicrobia, knowledge about cell division is mainly restricted to the recent report of ftsZ in the closely related genera Prosthecobacter and Verrucomicrobium. In this study, genes of the conserved division and cell wall (dcw) cluster (ddl, ftsQ, ftsA, and ftsZ) were characterized in all verrucomicrobial subdivisions (1 to 4) with cultivable representatives (1 to 4). Sequence analyses and transcriptional analyses in Verrucomicrobia and genome data analyses in Lentisphaerae suggested that cell division is based on FtsZ in all verrucomicrobial subdivisions and possibly also in the sister phylum Lentisphaerae. Comprehensive sequence analyses of available genome data for representatives of Verrucomicrobia, Lentisphaerae, Chlamydiae, and Planctomycetes strongly indicate that their last common ancestor possessed a conserved, ancestral type of dcw gene cluster and an FtsZ-based cell division mechanism. This implies that Planctomycetes and Chlamydiae may have shifted independently to a non-FtsZ-based cell division mechanism after their separate branchings from their last common ancestor with Verrucomicrobia

    Prognostic significance of endogenous adhesion/growth-regulatory lectins in lung cancer

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    Objective: To determine the expression of endogenous adhesion/growth-regulatory lectins and their binding sites using labeled tissue lectins as well as the binding profile of hyaluronic acid as an approach to define new prognostic markers. Methods: Sections of paraffin-embedded histological material of 481 lungs from lung tumor patients following radical lung excision processed by a routine immunohistochemical method (avidin-biotin labeling, DAB chromogen). Specific antibodies against galectins-1 and - 3 and the heparin-binding lectin were tested. Staining by labeled galectins and hyaluronic acid was similarly visualized by a routine protocol. After semiquantitative assessment of staining, the results were compared with the pT and pN stages and the histological type. Survival was calculated by univariate and multivariate methods. Results: Binding of galectin-1 and its expression tended to increase, whereas the parameters for galectin-3 decreased in advanced pT and pN stages at a statistically significant level. The number of positive cases was considerably smaller among the cases with small cell lung cancer than in the group with non-small-cell lung cancer, among which adenocarcinomas figured prominently with the exception of galectin-1 expression. Kaplan-Meier computations revealed that the survival rate of patients with galectin-3-binding or galectin-1-expressing tumors was significantly poorer than that of the negative cases. In the multivariate calculations of survival lymph node metastases ( p < 0.0001), histological type ( p = 0.003), galectin-3-binding capacity ( p = 0.01), galectin-3 expression ( p = 0.03) and pT status ( p = 0.003) proved to be independent prognostic factors, not correlated with the pN stage. Conclusion: The expression and the capacity to bind the adhesion/growth regulatory galectin-3 is defined as an unfavorable prognostic factor not correlated with the pTN stage. Copyright (C) 2005 S. Karger AG, Basel

    Exchange bias in Fe/EuTe(111) bilayers

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    We report on the investigation of the exchange bias effect in Fe layers on EuTe(111), an antiferromagnetic semiconductor. For this ferromagnet (FM)/semiconducting antiferromagnet (AFM) exchange bias system, we have found positive and negative exchange bias effect (EB). Fresh samples exhibit positive EB, independently of the applied cooling field, indicating antiferromagnetic coupling between the FM and the AFM layers at the Fe/EuTe(111) interface. The change in EB with time, from positive EB for fresh samples to negative EB after short time,is attributed to aging effects at the Fe/EuTe interface. (c) 2007 American Institute of Physics.102

    The CD3-Zeta Chimeric Antigen Receptor Overcomes TCR Hypo-Responsiveness of Human Terminal Late-Stage T Cells

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    Adoptive therapy of malignant diseases with tumor-specific cytotoxic T cells showed remarkable efficacy in recent trials. Repetitive T cell receptor (TCR) engagement of target antigen, however, inevitably ends up in hypo-responsive cells with terminally differentiated KLRG-1+ CD57+ CD7− phenotype limiting their therapeutic efficacy. We here revealed that hypo-responsiveness of CMV-specific late-stage CD8+ T cells is due to reduced TCR synapse formation compared to younger cells. Membrane anchoring of TCR components contributes to T cell hypo-responsiveness since dislocation of galectin-3 from the synapse by swainsonine restored both TCR synapse formation and T cell response. Transgenic expression of a CD3-zeta signaling chimeric antigen receptor (CAR) recovered hypo-responsive T cells to full effector functions indicating that the defect is restricted to TCR membrane components while synapse formation of the transgenic CAR was not blocked. CAR engineered late-stage T cells released cytokines and mediated redirected cytotoxicity as efficiently as younger effector T cells. Our data provide a rationale for TCR independent, CAR mediated activation in the adoptive cell therapy to avoid hypo-responsiveness of late-stage T cells upon repetitive antigen encounter
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