Genome Integrity: A new open access journal

The full and final version of this article can be found at the link belowThis article has been made available through the Brunel Open Access Publishing Fund.This article is available through the Brunel Open Access Publishing Fund

An analysis of finite and non-finite verbs in selected passages in the Gospel of Mark

This thesis examines finite and non-finite verbs in The Gospel of Mark 15:22-39 and 16:1-7 in Greek, Latin, Gothic and Old English. The study is a comparison of the person, tense, mood and voice in all four languages, as well as a comparison of strength, weakness and class of the Germanic verbs. Also, attention was paid to the use of available cognates for subsequent translations

On the rate of convergence in periodic homogenization of scalar first-order ordinary differential equations

In this paper, we study the rate of convergence in periodic homogenization of scalar ordinary differential equations. We provide a quantitative error estimate between the solutions of a first-order ordinary differential equation with rapidly oscillating coefficients and the limiting homogenized solution. As an application of our result, we obtain an error estimate for the solution of some particular linear transport equations

Curl-Conforming Vector Bases for Hybrid Meshes: A New Paradigm for Pyramid Elements

A simple procedure for obtaining hierarchical curlconforming pyramid bases has been obtained by shifting to a new paradigm that requires the mapping of the pyramidal cell into a cube and then directly imposing the conformity of the vector bases with those used on adjacent differently shaped cells (tetrahedra, hexahedra and triangular prisms). This summary discusses and generalizes some features of the new construction method recently published elsewhere

Identification of dermatophytes by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

In this study we evaluated the suitability of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) for the identification of dermatophytes in diagnostic laboratories. First, a spectral database was built with 108 reference strains belonging to 18 species of the anamorphic genera Epidermophyton, Microsporum and Trichophyton. All strains were well characterized by morphological criteria and ITS sequencing (gold standard). The dendrogram resulting from MALDI-TOF mass spectra was almost identical with the phylogenetic tree based on ITS sequencing. Subsequently, MALDI-TOF MS SuperSpectra were created for the identification of Epidermophyton floccosum, Microsporium audouinii, M. canis, M. gypseum (teleomorph: Arthroderma gypseum), M. gypseum (teleomorph: A. incurvatum), M. persicolor, A. benhamiae (Tax. Entity 3 and Am-Eur. race), T. erinacei, T. interdigitale (anthropophilic and zoophilic populations), T. rubrum/T. violaceum, T. tonsurans and T. terrestre. Because T. rubrum and T. violaceum did not present enough mismatches, a SuperSpectrum covering both species was created, and differentiation between them was done by comparison of eight specific peptide masses. In the second part of this study, MALDI-TOF MS with the newly created SuperSpectra was tested using 141 clinical isolates representing nine species. Analyses were done with 3-day-old cultures. Results were compared to morphological identification and ITS sequencing; 135/141 (95.8%) strains were correctly identified by MALDI-TOF MS compared to 128/141 (90.8%) by morphology. Therefore, MALDI-TOF MS has proven to be a useful and rapid identification method for dermatophyte

Breastfeeding does not influence the development of inhibitors in haemophilia.

Our aim was to test the hypothesis that breastfeeding may reduce development of inhibitors in male infants with haemophilia by inducing an oral immune tolerance to factor VIII. To achieve that goal, we performed a structured epidemiological survey comprising all males born with severe haemophilia A (in all 100 patients, 19 with inhibitors) or haemophilia B (in all 16 patients, six with inhibitors) in Sweden in 1980-99. Our results show no protective effect of breastfeeding

Self help groups in a city of Tuscany: Reconstruction of the second generation model of work for professionals and services

This study is part of a more extensive project aimed to investigate the effectiveness of self-help group participation in improving quality of life in mental disease. The study is taking place in the Tuscany Region, in Italy. In the first qualitative step of analysis researchers are interested in describing the specific features of the psychiatric self-help movement in Tuscany, comparing different realities, networks, kind of groups. Therefore, our aim is to collect exhaustive information to describe how self-help system work in different provinces at the present moment. The implementation of groups for psychiatric problems is quite young in Italy.  Because of a lack of specific regulation in the directives of the Italian health care system, every local service has implemented groups differently, sometimes enhancing, sometimes dismissing them. Prato, near Florence, is one of the more interesting context for the birth of psychiatric self-help movement in the region: public health services improved groups since early 90’s, it was one of the first self-help reality linked to services in the entire region. Now we are in a “second generation” of professionals, and the original meaning of groups seems to be transformed, sometimes misunderstood. Our objectives of study head us toward an in depth analysis of self-help phenomenon in Prato

Self help groups in a city of Tuscany: Reconstruction of the second generation model of work for professionals and services

This study is part of a more extensive project aimed to investigate the effectiveness of self-help group participation in improving quality of life in mental disease. The study is taking place in the Tuscany Region, in Italy. In the first qualitative step of analysis researchers are interested in describing the specific features of the psychiatric self-help movement in Tuscany, comparing different realities, networks, kind of groups. Therefore, our aim is to collect exhaustive information to describe how self-help system work in different provinces at the present moment. The implementation of groups for psychiatric problems is quite young in Italy.  Because of a lack of specific regulation in the directives of the Italian health care system, every local service has implemented groups differently, sometimes enhancing, sometimes dismissing them. Prato, near Florence, is one of the more interesting context for the birth of psychiatric self-help movement in the region: public health services improved groups since early 90’s, it was one of the first self-help reality linked to services in the entire region. Now we are in a “second generation” of professionals, and the original meaning of groups seems to be transformed, sometimes misunderstood. Our objectives of study head us toward an in depth analysis of self-help phenomenon in Prato

A Class of N=1 Supersymmetric RG Flows from Five-dimensional N = 8 Supergravity

We consider the holographic dual of a general class of N=1* flows in which all three chiral multiplets have independent masses, and in which the corresponding Yang-Mills scalars can develop particular supersymmetry-preserving vevs. We also allow the gaugino to develop a vev. This leads to a six parameter subspace of the supergravity scalar action, and we show that this is a consistent truncation, and obtain a superpotential that governs the N=1* flows on this subspace. We analyse some of the structure of the superpotential, and check consistency with the asymptotic behaviour near the UV fixed point. We show that the dimensions of the six couplings obey a sum rule all along the N=1* flows. We also show how our superpotential describes part of the Coulomb branch of the non-trivial N=1 fixed point theory.Comment: 14 pages; harvmac. New version has only minor correction