The Role of the Mangement Sciences in Research on Personalization

We present a review of research studies that deal with personalization. We synthesize current knowledge about these areas, and identify issues that we envision will be of interest to researchers working in the management sciences. We take an interdisciplinary approach that spans the areas of economics, marketing, information technology, and operations. We present an overarching framework for personalization that allows us to identify key players in the personalization process, as well as, the key stages of personalization. The framework enables us to examine the strategic role of personalization in the interactions between a firm and other key players in the firm's value system. We review extant literature in the strategic behavior of firms, and discuss opportunities for analytical and empirical research in this regard. Next, we examine how a firm can learn a customer's preferences, which is one of the key components of the personalization process. We use a utility-based approach to formalize such preference functions, and to understand how these preference functions could be learnt based on a customer's interactions with a firm. We identify well-established techniques in management sciences that can be gainfully employed in future research on personalization.CRM, Persoanlization, Marketing, e-commerce,

High performance concrete with steel slag aggregate

U radu se analizira utjecaj starenja čeličanske zgure kao agregata na mehanička svojstva betona visokih uporabnih svojstava. Razmatra se utjecaj raznih vremena starenja na mehanička svojstva betona. Uočeno je da proces starenja zgure utječe na svojstva ovog betona. Tlačna čvrstoća betona raste usporedo s porastom vremena starenja. Savojna čvrstoća, Youngov modul i udarna čvrstoća rastu slično kao i tlačna čvrstoća. Obradivost betona i gubitak abrazijom smanjuju se s povećanjem vremena starenja.The effect of the steel slag aggregate aging on mechanical properties of the high performance concrete is analysed in the paper. The effect of different aging periods of steel slag aggregate on mechanical properties of high performance concrete is studied. It was observed that properties of this concrete are affected by the steel slag aggregate aging process. The compressive strength increases with an increase in the aging period of steel slag aggregate. The flexural strength, Young’s modulus, and impact strength of concrete, increase at the rate similar to that of the compressive strength. The workability and the abrasion loss of concrete decrease with an increase of the steel slag aggregate aging period

Subtle Radiological Features of Splenic Avulsion following Abdominal Trauma

Splenic trauma in children following blunt abdominal injury is usually treated by nonoperative management (NOM). Splenectomy following abdominal trauma is rare in children. NOM is successful as in the majority of instances the injury to the spleen is contained within its capsule or a localised haematoma. Rarely, the spleen may suffer from an avulsion injury that causes severe uncontrollable bleeding and necessitates an emergency laparotomy and splenectomy. We report two cases of children requiring splenectomy following severe blunt abdominal injury. In both instances emergency laparotomy was undertaken for uncontrollable bleeding despite resuscitation. The operating team was unaware of the precise source of bleeding preoperatively. Retrospective review of the computed tomography (CT) scans revealed subtle radiological features that indicate splenic avulsion. We wish to highlight these radiological features of splenic avulsion as they can help to focus management decisions regarding the need/timing for a laparotomy following blunt abdominal trauma in children

Decreased Placental FPR2 in Early Pregnancies That Later Developed Small-For-Gestation Age: A Potential Role of FPR2 in the Regulation of Epithelial-Mesenchymal Transition

We reported earlier that an anti-inflammatory small peptide receptor-formyl peptide receptor-2 (FPR2) was significantly decreased in placentas from third trimester pregnancies complicated with fetal growth restriction (FGR), compared to placentas from uncomplicated control pregnancies, suggesting FPR2 may play a role in the development of FGR. The aim of this study is to investigate whether the actions of FPR2 alters placental growth process in humans. Accordingly, using small-for-gestation age (SGA) as a proxy for FGR, we hypothesize that FPR2 expression is decreased in first-trimester placentas of women who later manifest FGR, and contributes to aberrant trophoblast function and the development of FGR. Chorionic villus sampling (CVS) tissues were collected at 10-12 weeks gestation in 70 patients with singleton fetuses; surplus tissue was used. Real-time PCR and immunoassays were performed to quantitate FPR2 gene and protein expression. Silencing of FPR2 was performed in two independent, trophoblast-derived cell lines, HTR-8/SVneo and JEG-3 to investigate the functional consequences of FPR2 gene downregulation. FPR2 mRNA relative to 18S rRNA was significantly decreased in placentae from SGA-pregnancies (n = 28) compared with controls (n = 52) (p < 0.0001). Placental FPR2 protein was significantly decreased in SGA compared with control (n = 10 in each group, p < 0.05). Proliferative, migratory and invasive potential of the human placental-derived cell lines, HTR-8/SVneo and JEG-3 were significantly reduced in siFPR2 treated cells compared with siCONT control groups. Down-stream signaling molecules, STAT5B and SOCS3 were identified as target genes of FPR2 action in the trophoblast-derived cell lines and in SGA and control chorionic villous tissues. FPR2 is a novel regulator of key molecular pathways and functions in placental development, and its decreased expression in women destined to develop FGR reinforces a placental origin of SGA/FGR, and that it contributes to causing the development of SGA/FGR

Evaluating Greek equity funds using data envelopment analysis

This study assesses the relative performance of Greek equity funds employing a non-parametric method, specifically Data Envelopment Analysis (DEA). Using an original sample of cost and operational attributes we explore the e¤ect of each variable on funds' operational efficiency for an oligopolistic and bank-dominated fund industry. Our results have significant implications for the investors' fund selection process since we are able to identify potential sources of inefficiencies for the funds. The most striking result is that the percentage of assets under management affects performance negatively, a conclusion which may be related to the structure of the domestic stock market. Furthermore, we provide evidence against the notion of funds' mean-variance efficiency

Impact Resistance and Strength Development of Fly Ash Based Self-compacting Concrete

The development of self-compacting concrete using alternative materials is expanding in recent years due to the technical and economic benefits of the mixture. This study focuses on the structural and compositional behavior of sodium hydroxide (NaOH)-activated fly ash based self-compacting concrete (SCC). Fly ash was partially replaced with Ordinary Portland Cement from 0–30%. The tests performed on concrete samples include workability, strength, microstructural, and impact resistance. The results showed that activated fly ash reduces the heat of the hydration process of the concrete mixture but enhances pozzolanic reactions, which led to increased strength properties. The addition of activated fly ash modifies the mineralogy of the concrete, as evident in strength characteristics. The best performance of the activated fly ash based SCC, in terms of strength, was found at 10–15% substitutions, which can somewhat reduce the cost of production of SCC and strength improvement advantage

Impact Resistance and Strength Development of Fly Ash Based Selfcompacting Concrete

The development of self-compacting concrete using alternative materials is expanding in recent years due to the technical and economic benefits of the mixture. This study focuses on the structural and compositional behavior of sodium hydroxide (NaOH)-activated fly ash based self-compacting concrete (SCC). Fly ash was partially replaced with Ordinary Portland Cement from 0– 30%. The tests performed on concrete samples include workability, strength, microstructural, and impact resistance. The results showed that activated fly ash reduces the heat of the hydration process of the concrete mixture but enhances pozzolanic reactions, which led to increased strength properties. The addition of activated fly ash modifies the mineralogy of the concrete, as evident in strength characteristics. The best performance of the activated fly ash based SCC, in terms of strength, was found at 10–15% substitutions, which can somewhat reduce the cost of production of SCC and strength improvement advantage

Non-steroidal Anti-inflammatory Drugs (NSAIDs) Use in Primary Health Care Centers in A’Seeb, Muscat: A Clinical Audit

Objective: We sought to assess the trend of non-steroidal anti-inflammatory drug (NSAID) use in primary health care institutions located in A’Seeb, a province in the capital city of Oman, Muscat. Additionally, we evaluated the relationship between a physician’s years of experience and the number of prescription issued, as well as the presence of risk factors and side effects in the patients who received these prescriptions. Method: A clinical audit was conducted in four primary health care centers in the Muscat region over a one-week period in April 2014. The target population included patients aged 18 years or over who attended one of the four health centers and were prescribed NSAIDs. Overall, 272 patients were recruited by systematic random sampling. The data were collected by two methods: direct face-to-face interviews and evaluations of the patient’s electronic medical file. The prescribing doctors were blind to the audit. The collected information included patients demographics, past and current medical history of related comorbidities, NSAID type, dose, duration and indications for use, concomitant warfarin or/and aspirin prescriptions, and co-prescription of gastroprotective agents. Results: In total, 15% of patients received an NSAID prescription: females were issued more prescriptions than males. The percentage of patients who received an NSAID prescription across the health centers ranged from 9% to 24%. The main reason for prescribing NSAIDs was musculoskeletal problems. The most frequently prescribed NSAID was ibuprofen. Sixteen percent of patients who received an NSAID prescription had a risk factor related to its use. The mean and median duration of the NSAID prescriptions of all types were 5.6 and 5.0 days, respectively. Physicians with a greater number of years experience prescribed more NSAIDs. Conclusion: Our study showed that the number of prescriptions of NSAIDs among various institutes varied, which could reflect the level of awareness concerning NSAID risks among the prescribing doctors. NSAIDs were prescribed for patients with comorbidities and patients with previously documented side effects without considering protective agents. Therefore, we suggest that the use of these medications is controlled, especially in high-risk populations

Shear Resistance of portal Frame Reinforced with Bamboo and Steel Rebar: Experimental and Numerical Evaluation

The main objective of this study is to evaluate the shear resistance of portal frame fabricated with bamboo and steel rebar by following experimental and numerical approaches. In support of sustainable construction, bamboo stripes were utilized as a partial replacement of steel rebar at tension zone of members that are subjected to lateral loading. The performance of nominal portal frame, which are fabricated with steel reinforcement was compared to the portal frames having several replacements of steel reinforcement with bamboo, in terms of seismic resistance and lateral load capacity. The experimental data was correlated based on software analysis using ABAQUS. The partial replacement of steel with bamboo under tension zone of the beams in portal frame was found to be highly effective, and also that the flexural rigidity of the partial bamboo reinforced frame was slightly higher than the nominal portal frame. This study provides insight on the possibility of reinforcing structural members with bamboo, when lateral loading is imminent on the structure

Role of the Placental Vitamin D Receptor in Modulating Feto-Placental Growth in Fetal Growth Restriction and Preeclampsia-Affected Pregnancies

Fetal growth restriction (FGR) is a common pregnancy complication that affects up to 5% of pregnancies worldwide. Recent studies demonstrate that Vitamin D deficiency is implicated in reduced fetal growth, which may be rescued by supplementation of Vitamin D. Despite this, the pathway(s) by which Vitamin D modulate fetal growth remains to be investigated. Our own studies demonstrate that the Vitamin D receptor (VDR) is significantly decreased in placentae from human pregnancies complicated by FGR and contributes to abnormal placental trophoblast apoptosis and differentiation and regulation of cell-cycle genes in vitro. Thus, Vitamin D signaling is important for normal placental function and fetal growth. This review discusses the association of Vitamin D with fetal growth, the function of Vitamin D and its receptor in pregnancy, as well as the functional significance of a placental source of Vitamin D in FGR. Additionally, we propose that for Vitamin D to be clinically effective to prevent and manage FGR, the molecular mechanisms of Vitamin D and its receptor in modulating fetal growth requires further investigation