Linear Temperature Variation of the Penetration Depth in YBCO Thin Films

We have measured the penetration depth $\lambda(T)$ on $\rm YBa_{2}Cu_{3}O_{7}$ thin films from transmission at 120, 330 and 510~GHz, between 5 and 50~K. Our data yield simultaneously the absolute value and the temperature dependence of $\lambda(T)$. In high quality films $\lambda(T)$ exhibits the same linear temperature dependence as single crystals, showing its intrinsic nature, and $\lambda(0)=1750\,{\rm \AA}$. In a lower quality one, the more usual $T^2$ dependence is found, and $\lambda(0)=3600\,{\rm \AA}$. This suggests that the $T^2$ variation is of extrinsic origin. Our results put the $d$-wave like interpretation in a much better position.Comment: 12 pages, revtex, 4 uuencoded figure

An analytic approximation to the Diffusion Coefficient for the periodic Lorentz Gas

An approximate stochastic model for the topological dynamics of the periodic triangular Lorentz gas is constructed. The model, together with an extremum principle, is used to find a closed form approximation to the diffusion coefficient as a function of the lattice spacing. This approximation is superior to the popular Machta and Zwanzig result and agrees well with a range of numerical estimates.Comment: 13 pages, 4 figure

Inverse Spin Hall Effect in nanometer-thick YIG/Pt system

High quality nanometer-thick (20 nm, 7 nm and 4 nm) epitaxial YIG films have been grown on GGG substrates using pulsed laser deposition. The Gilbert damping coefficient for the 20 nm thick films is 2.3 x 10-4 which is the lowest value reported for sub-micrometric thick films. We demonstrate Inverse spin Hall effect (ISHE) detection of propagating spin waves using Pt. The amplitude and the lineshape of the ISHE voltage correlate well to the increase of the Gilbert damping when decreasing thickness of YIG. Spin Hall effect based loss-compensation experiments have been conducted but no change in the magnetization dynamics could be detected

Fréquence relative des isolements de virus de diverses familles chez des veaux malades ou apparemment sains, dans le département de l’Aube

Au cours d’une enquête consacrée, dans le département de l’Aube, à la « mortalité des veaux », plusieurs centaines de prélèvements sont effectués, sur 243 sujets sains ou malades. Vingt trois souches de virus, parmi lesquels Picornavirus, Paramyxovirus, Herpes virus, virus de la « maladie des muqueuses » sont isolées. La fré quence relative des isolements, en fonction des observations épizootiologiques et cliniques correspondantes, de l’âge des sujets, de la nature des prélèvements effectués, le rôle étiologique éventuel de ces divers virus, sont analysés et discutés

Comparaison des résultats obtenus, par diverses techniques sérologiques, à partir des mêmes sérums, avec des antigènes préparés à partir de la même souche de « Rakeia Ovis » («Virus» de l 'avortement de la brebis)

La confrontation des résultats obtenus, par quatre méthodes sérologiques différentes, à partir des mêmes sérums ovins en pré sence du même antigène « Rakeia ovis » confirme la complexité de la réaction antigène-anticorps dans ce domaine ainsi que la nécessité de définir la signification de chacune des méthodes avant de comparer leurs sensibilités réciproques

Propriétés hémagglutinantes du « virus » de l’avortement enzootique des petits ruminants (souches de « Rakeia » d’origine ovine et caprine). Note préliminaire

— Un antigène purifié, préparé à partir de souches de « Rakeia » d’origine ovine et caprine entretenues en ovoculture, hémagglutine à pH 6, à 23°, sans élution spontanée, les érythrocytes de l’oie, non ceux d’Homme, de souris, de cobaye, de poussin d’un jour et de poulet. — Cette hémagglutination est inhibée par les antisérums spécifiques, à des titres analogues à ceux que l’on peut mesurer, dans les mêmes sérums, par d’autres réactions sérologiques (par exemple l’immunofluorescence)

Determination of no-observed effect level (NOEL)-biomarker equivalents to interpret biomonitoring data for organophosphorus pesticides in children

<p>Abstract</p> <p>Background</p> <p>Environmental exposure to organophosphorus pesticides has been characterized in various populations, but interpretation of these data from a health risk perspective remains an issue. The current paper proposes biological reference values to help interpret biomonitoring data related to an exposure to organophosphorus pesticides in children for which measurements of alkylphosphate metabolites are available.</p> <p>Methods</p> <p>Published models describing the kinetics of malathion and chlorpyrifos in humans were used to determine no-observed effect level – biomarker equivalents for methylphosphates and ethylphosphates, respectively. These were expressed in the form of cumulative urinary amounts of alkylphosphates over specified time periods corresponding to an absorbed no-observed effect level dose (derived from a published human exposure dose) and assuming various plausible exposure scenarios. Cumulative amounts of methylphosphate and ethylphosphate metabolites measured in the urine of a group of Quebec children were then compared to the proposed biological reference values.</p> <p>Results</p> <p>From a published no-observed effect level dose for malathion and chlorpyrifos, the model predicts corresponding oral biological reference values for methylphosphate and ethylphosphate derivatives of 106 and 52 nmol/kg of body weight, respectively, in 12-h nighttime urine collections, and dermal biological reference values of 40 and 32 nmol/kg of body weight. Out of the 442 available urine samples, only one presented a methylphosphate excretion exceeding the biological reference value established on the basis of a dermal exposure scenario and none of the methylphosphate and ethylphosphate excretion values were above the obtained oral biological reference values, which reflect the main exposure route in children.</p> <p>Conclusion</p> <p>This study is a first step towards the development of biological guidelines for organophophorus pesticides using a toxicokinetic modeling approach, which can be used to provide a health-based interpretation of biomonitoring data in the general population.</p

Further investigation of confirmed urinary tract infection (UTI) in children under five years: a systematic review.

Background: Further investigation of confirmed UTI in children aims to prevent renal scarring and future complications. Methods: We conducted a systematic review to determine the most effective approach to the further investigation of confirmed urinary tract infection (UTI) in children under five years of age. Results: 73 studies were included. Many studies had methodological limitations or were poorly reported. Effectiveness of further investigations: One study found that routine imaging did not lead to a reduction in recurrent UTIs or renal scarring. Diagnostic accuracy: The studies do not support the use of less invasive tests such as ultrasound as an alternative to renal scintigraphy, either to rule out infection of the upper urinary tract (LR- = 0.57, 95%CI: 0.47, 0.68) and thus to exclude patients from further investigation or to detect renal scarring (LR+ = 3.5, 95% CI: 2.5, 4.8). None of the tests investigated can accurately predict the development of renal scarring. The available evidence supports the consideration of contrast-enhanced ultrasound techniques for detecting vesico-ureteric reflux (VUR), as an alternative to micturating cystourethrography (MCUG) (LR+ = 14.1, 95% CI: 9.5, 20.8; LR- = 0.20, 95%CI: 0.13, 0.29); these techniques have the advantage of not requiring exposure to ionising radiation. Conclusion: There is no evidence to support the clinical effectiveness of routine investigation of children with confirmed UTI. Primary research on the effectiveness, in terms of improved patient outcome, of testing at all stages in the investigation of confirmed urinary tract infection is urgently required

No role for quality scores in systematic reviews of diagnostic accuracy studies

BACKGROUND: There is a lack of consensus regarding the use of quality scores in diagnostic systematic reviews. The objective of this study was to use different methods of weighting items included in a quality assessment tool for diagnostic accuracy studies (QUADAS) to produce an overall quality score, and to examine the effects of incorporating these into a systematic review. METHODS: We developed five schemes for weighting QUADAS to produce quality scores. We used three methods to investigate the effects of quality scores on test performance. We used a set of 28 studies that assessed the accuracy of ultrasound for the diagnosis of vesico-ureteral reflux in children. RESULTS: The different methods of weighting individual items from the same quality assessment tool produced different quality scores. The different scoring schemes ranked different studies in different orders; this was especially evident for the intermediate quality studies. Comparing the results of studies stratified as "high" and "low" quality based on quality scores resulted in different conclusions regarding the effects of quality on estimates of diagnostic accuracy depending on the method used to produce the quality score. A similar effect was observed when quality scores were included in meta-regression analysis as continuous variables, although the differences were less apparent. CONCLUSION: Quality scores should not be incorporated into diagnostic systematic reviews. Incorporation of the results of the quality assessment into the systematic review should involve investigation of the association of individual quality items with estimates of diagnostic accuracy, rather than using a combined quality score