1,314 research outputs found

    Understanding the High Attrition Rates of Male Collegiate Basketball Student-Athletes

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    The purpose of this applied study was to gain a better understanding of the high attrition rates among male collegiate basketball student-athletes and to recommend practices that institutions can implement to address and solve this increasing problem. The study utilized a multimethod approach and collected data through a series of interviews, a focus group, and a survey. Based on the results of the data, a series of recommendations have been included to address the high attrition rates among male collegiate basketball student-athletes. Most of the recommendations are based on how the recruiting process can be better handled by representatives of the institutions as well as by the potential student-athletes that are being recruited. Additional recommendations are based on Tinto’s theory of departure, which states that a student who is integrated and involved with a community is more likely to be retained

    Novel roles for mucin 1 in the kidney

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    Purpose of review Recent studies in the kidney have revealed that the well characterized tumor antigen mucin 1 (MUC1/Muc1) also has numerous functions in the normal and injured kidney. Recent findings Mucin 1 is a transmembrane mucin with a robust glycan-dependent apical targeting signal and efficient recycling from endosomes. It was recently reported that the TRPV5 calcium channel is stabilized on the cell surface by galectin-dependent cross-linking to mucin 1, providing a novel mechanism for regulation of ion channels and normal electrolyte balance. Our recent studies in mice show that Muc 1 is induced after ischemia, stabilizing hypoxia-inducible factor 1 (HIF-1)α and β-catenin levels, and transactivating the HIF-1 and β-catenin protective pathways. However, prolonged induction of either pathway in the injured kidney can proceed from apparent full recovery to chronic kidney disease. A very recent report indicates that aberrant activation of mucin 1 signaling after ischemic injury in mice and humans is associated with development of chronic kidney disease and fibrosis. A frameshift mutation in MUC1 was recently identified as the genetic lesion causing medullary cystic kidney disease type 1, now appropriately renamed MUC1 Kidney Disease. Summary Studies of mucin 1 in the kidney now reveal significant functions for the extracellular mucin-like domain and signaling through the cytoplasmic tail

    Observing Gravitational-Wave Transient GW150914 with Minimal Assumptions

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    The gravitational-wave signal GW150914 was first identified on September 14, 2015, by searches for short-duration gravitational-wave transients. These searches identify time-correlated transients in multiple detectors with minimal assumptions about the signal morphology, allowing them to be sensitive to gravitational waves emitted by a wide range of sources including binary black hole mergers. Over the observational period from September 12 to October 20, 2015, these transient searches were sensitive to binary black hole mergers similar to GW150914 to an average distance of ∼600  Mpc. In this paper, we describe the analyses that first detected GW150914 as well as the parameter estimation and waveform reconstruction techniques that initially identified GW150914 as the merger of two black holes. We find that the reconstructed waveform is consistent with the signal from a binary black hole merger with a chirp mass of ∼30  M⊙ and a total mass before merger of ∼70  M⊙ in the detector frame

    Results of the Deepest All-Sky Survey for Continuous Gravitational Waves on LIGO S6 Data Running on the Einstein@Home Volunteer Distributed Computing Project

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    We report results of a deep all-sky search for periodic gravitational waves from isolated neutron stars in data from the S6 LIGO science run. The search was possible thanks to the computing power provided by the volunteers of the Einstein@Home distributed computing project

    The Rate of Binary Black Hole Mergers Inferred From Advanced LIGO Observations Surrounding GW150914

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    A transient gravitational-wave signal, GW150914, was identified in the twin Advanced LIGO detectors on 2015 September 2015 at 09:50:45 UTC. To assess the implications of this discovery, the detectors remained in operation with unchanged configurations over a period of 39 days around the time of the signal. At the detection statistic threshold corresponding to that observed for GW150914, our search of the 16 days of simultaneous two-detector observational data is estimated to have a false-alarm rate (FAR) o

    Characterization of Transient Noise in Advanced LIGO Relevant to Gravitational Wave Signal GW150914

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    On September 14, 2015, a gravitational wave signal from a coalescing black hole binary system was observed by the Advanced LIGO detectors. This paper describes the transient noise backgrounds used to determine the significance of the event (designated GW150914) and presents the results of investigations into potential correlated or uncorrelated sources of transient noise in the detectors around the time of the event. The detectors were operating nominally at the time of GW150914. We have ruled out environmental influences and non-Gaussian instrument noise at either LIGO detector as the cause of the observed gravitational wave signal

    Directly Comparing GW150914 With Numerical Solutions of Einstein\u27s Equations for Binary Black Hole Coalescence

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    We compare GW150914 directly to simulations of coalescing binary black holes in full general relativity, including several performed specifically to reproduce this event. Our calculations go beyond existing semianalytic models, because for all simulations—including sources with two independent, precessing spins—we perform comparisons which account for all the spin-weighted quadrupolar modes, and separately which account for all the quadrupolar and octopolar modes. Consistent with the posterior distributions reported by Abbott et al. [Phys. Rev. Lett. 116, 241102 (2016)] (at the 90% credible level), we find the data are compatible with a wide range of nonprecessing and precessing simulations. Follow-up simulations performed using previously estimated binary parameters most resemble the data, even when all quadrupolar and octopolar modes are included. Comparisons including only the quadrupolar modes constrain the total redshifted mass Mz ∈ ½64 M⊙ − 82 M⊙_, mass ratio 1=q ¼ m2=m1 ∈ ½0.6; 1_, and effective aligned spin χeff ∈ ½−0.3; 0.2_, where χeff ¼ ðS1=m1 þ S2=m2Þ · ˆL=M. Including both quadrupolar and octopolar modes, we find the mass ratio is even more tightly constrained. Even accounting for precession, simulations with extreme mass ratios and effective spins are highly inconsistent with the data, at any mass. Several nonprecessing and precessing simulations with similar mass ratio and χeff are consistent with the data. Though correlated, the components’ spins (both in magnitude and directions) are not significantly constrained by the data: the data is consistent with simulations with component spin magnitudes a1;2 up to at least 0.8, with random orientations. Further detailed follow-up calculations are needed to determine if the data contain a weak imprint from transverse (precessing) spins. For nonprecessing binaries, interpolating between simulations, we reconstruct a posterior distribution consistent with previous results. The final black hole’s redshifted mass is consistent with Mf;z in the range 64.0 M⊙ − 73.5 M⊙ and the final black hole’s dimensionless spin parameter is consistent with af ¼ 0.62–0.73. As our approach invokes no intermediate approximations to general relativity and can strongly reject binaries whose radiation is inconsistent with the data, our analysis provides a valuable complement to Abbott et al. [Phys. Rev. Lett. 116, 241102 (2016)]

    GW151226: Observation of Gravitational Waves from a 22-Solar-Mass Binary Black Hole Coalescence

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    We report the observation of a gravitational-wave signal produced by the coalescence of two stellar-mass black holes. The signal, GW151226, was observed by the twin detectors of the Laser Interferometer Gravitational-Wave Observatory (LIGO) on December 26, 2015 at 03:38:53 UTC. The signal was initially identified within 70 s by an online matched-filter search targeting binary coalescences. Subsequent off-line analyses recovered GW151226 with a network signal-to-noise ratio of 13 and a significance greater than 5 σ. The signal persisted in the LIGO frequency band for approximately 1 s, increasing in frequency and amplitude over about 55 cycles from 35 to 450 Hz, and reached a peak gravitational strain of 3.4+0.7−0.9×10−22. The inferred source-frame initial black hole masses are 14.2+8.3−3.7M⊙ and 7.5+2.3−2.3M⊙ and the final black hole mass is 20.8+6.1−1.7M⊙. We find that at least one of the component black holes has spin greater than 0.2. This source is located at a luminosity distance of 440+180−190 Mpc corresponding to a redshift 0.09+0.03−0.04. All uncertainties define a 90 % credible interval. This second gravitational-wave observation provides improved constraints on stellar populations and on deviations from general relativity
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