Moving Beyond the Welfare Standard of Psychological Well-Being for Nonhuman Primates: The Case of Chimpanzees

Since 1985, the US Animal Welfare Act and Public Health Service policy have required that researchers using nonhuman primates in biomedical and behavioral research develop a plan ‘‘for a physical environment adequate to promote the psychological well-being of primates.’’ In pursuing this charge, housing attributes such as social companionship, opportunities to express species-typical behavior, suitable space for expanded locomotor activity, and nonstressful relationships with laboratory personnel are dimensions that have dominated the discussion. Regulators were careful not to direct a specific set of prescriptions (i.e., engineering standards) for the attainment of these goals, but to leave the design of the programs substantially up to ‘‘professional judgment’’ at the local level. Recently, however, the Institute of Medicine, in its path-finding 2011 report on the necessity of chimpanzee use in research, bypassed this flexible and contingent concept, and instead, required as a central precondition that chimpanzees be housed in ‘‘ethologically appropriate’’ environments. In so doing, obligations of ethical treatment of one great ape species were elevated above the needs of some research. The evolution and significance of this change are discussed

Harry F. Harlow and Animal Research: Reflection on the Ethical Paradox

With respect to the ethical debate about the treatment of animals in biomedical and behavioral research, Harry F. Harlow represents a paradox. On the one hand, his work on monkey cognition and social development fostered a view of the animals as having rich subjective lives filled with intention and emotion. On the other, he has been criticized for the conduct of research that seemed to ignore the ethical implications of his own discoveries. The basis of this contradiction is discussed and propositions for current research practice are presented

Solving for Micro- and Macro- Scale Electrostatic Configurations Using the Robin Hood Algorithm

We present a novel technique by which highly-segmented electrostatic configurations can be solved. The Robin Hood method is a matrix-inversion algorithm optimized for solving high density boundary element method (BEM) problems. We illustrate the capabilities of this solver by studying two distinct geometry scales: (a) the electrostatic potential of a large volume beta-detector and (b) the field enhancement present at surface of electrode nano-structures. Geometries with elements numbering in the O(10^5) are easily modeled and solved without loss of accuracy. The technique has recently been expanded so as to include dielectrics and magnetic materials.Comment: 40 pages, 20 figure

Gender Differences in Attitudes Toward Animal Research

Although gender differences in attitudes toward animal research have been reported in the literature for some time, exploration into the nature of these differences has received less attention. This article examines gender differences in responses to a survey of attitudes toward the use of animals in research. The survey was completed by college students and consisted of items intended to tap different issues related to the animal research debate. Results indicated that women were more likely than men to support tenets of the animal protection movement. Likewise, women were more likely than men to favor increased restrictions on animal use and were more concerned than men about the suffering of research animals. Analysis of item contents suggested that women endorsed items reflecting a general caring for animals, were more willing than men to make personal sacrifices such as giving up meat and medical benefits in an effort to protect animals, and were more likely than men to question the use of animals in research on scientific grounds. Men, on the other hand, tended to emphasize the potential benefits arising from the use of animals in research

Gender Differences in Attitudes Toward Animal Research

Although gender differences in attitudes toward animal research have been reported in the literature for some time, exploration into the nature of these differences has received less attention. This article examines gender differences in responses to a survey of attitudes toward the use of animals in research. The survey was completed by college students and consisted of items intended to tap different issues related to the animal research debate. Results indicated that women were more likely than men to support tenets of the animal protection movement. Likewise, women were more likely than men to favor increased restrictions on animal use and were more concerned than men about the suffering of research animals. Analysis of item contents suggested that women endorsed items reflecting a general caring for animals, were more willing than men to make personal sacrifices such as giving up meat and medical benefits in an effort to protect animals, and were more likely than men to question the use of animals in research on scientific grounds. Men, on the other hand, tended to emphasize the potential benefits arising from the use of animals in research

Uncertainties of the CJK 5 Flavour LO Parton Distributions in the Real Photon

Radiatively generated, LO quark (u,d,s,c,b) and gluon densities in the real, unpolarized photon, calculated in the CJK model being an improved realization of the CJKL approach, have been recently presented. The results were obtained through a global fit to the experimental F2^gamma data. In this paper we present, obtained for the very first time in the photon case, an estimate of the uncertainties of the CJK parton distributions due to the experimental errors. The analysis is based on the Hessian method which was recently applied in the proton parton structure analysis. Sets of test parametrizations are given for the CJK model. They allow for calculation of its best fit parton distributions along with F2^gamma and for computation of uncertainties of any physical value depending on the real photon parton densities. We test the applicability of the approach by comparing uncertainties of example cross-sections calculated in the Hessian and Lagrange methods. Moreover, we present a detailed analysis of the chi^2 of the CJK fit and its relation to the data. We show that large chi^2/DOF of the fit is due to only a few of the experimental measurements. By excluding them chi^2/DOF approx 1 can be obtained.Comment: 28 pages, 8 eps figures, 2 Latex figures; FORTRAN programs available at http://www.fuw.edu.pl/~pjank/param.html; table 10, figure 10 and section 6 correcte

Testing Color Evaporation in Photon-Photon Production of J/Psi at CERN LEP II

The DELPHI Collaboration has recently reported the measurement of J/Psi production in photon-photon collisions at LEP II. These newly available data provide an additional proof of the importance of colored c bar{c} pairs for the production of charmonium because these data can only be explained by considering resolved photon processes. We show here that the inclusion of color octet contributions to the J/Psi production in the framework of the color evaporation model is able to reproduce this data. In particular, the transverse-momentum distribution of the J/Psi mesons is well described by this model.Comment: 10 pages, 5 Figures, Revtex

HERA prospects on Compositeness and New Vector Bosons

The absence of deviations from the Standard Model for the differential cross section ${d\sigma}/{dQ^2}$ at HERA is used to set limits on electron quark compositeness scale and on new vector bosons, especially the hadrophilic one recently introduced as a possible explanation for LEP/SLC and CDF anomalies.Comment: Latex file, 7 pages and 1 ps fig, few comments on others experiments are added, results are unchanged. To appear in Phys. Let.

Leading Chiral Contributions to the Spin Structure of the Proton

The leading chiral contributions to the quark and gluon components of the proton spin are calculated using heavy-baryon chiral perturbation theory. Similar calculations are done for the moments of the generalized parton distributions relevant to the quark and gluon angular momentum densities. These results provide useful insight about the role of pions in the spin structure of the nucleon, and can serve as a guidance for extrapolating lattice QCD calculations at large quark masses to the chiral limit.Comment: 8 pages, 2 figures; a typo in Ref. 7 correcte