Grosulfeimin and new related guaianolides from cynara scolymus L.

Three new guaianolides 11-H-13-rnethylsulfonylgrosheirnin 5 (Grosulfeirnin), 8-deoxy-11, 13-dihydroxygrosheimin 7 and 8-deoxy-11-hydroxy-13-chlorogrosheimin 8 have been isolated from the leaves of Cynara scolymus L. Besides, 8-epigrosheirnin 9 has been isolated for the ftrst time frorn this source. The structures were deterrnined by spectroscopical rnethods and by chernical correlations

Postpartum ovarian vein thrombosis after cesarean delivery: a case report

<p>Abstract</p> <p>Introduction</p> <p>Postpartum ovarian vein thrombosis is an uncommon complication; incidence varies between 0.002% and 0.05%. It most often occurs during the 2–15 days following delivery.</p> <p>Case presentation</p> <p>A 22-year-old pregnant woman at term presented to hospital with uterine contractions, abdominal pain, nausea and vomiting. After delivery an ovarian vein thrombosis was diagnosed.</p> <p>Conclusion</p> <p>Low-molecular weight heparin with broad-spectrum antibiotics are the accepted therapy in non-complicated cases of postpartum ovarian vein thrombosis.</p

Primary aldosteronism: A Japanese perspective

Primary aldosteronism (PA) is the most common cause of secondary hypertension, accounting for 10% of all hypertension. Far from being benign, hypertension due to PA is associated with high cardiovascular morbidity and mortality. However, PA is still underdiagnosed in general practice. Recent reports strongly recommend that identifying patients with PA is cost-beneficial based on improved cardiovascular outcomes afforded by specific surgical and medical treatment. This review provides an update of PA including controversial aspects of diagnosis and treatment

The GAPS Programme at TNG : LIV. A He I survey of close-in giant planets hosted by M-K dwarf stars with GIANO-B

Context. Atmospheric escape plays a fundamental role in shaping the properties of exoplanets. The metastable near-infrared (nIR) helium triplet at 1083.3 nm (He I) is a powerful proxy of extended and evaporating atmospheres. Aims: We used the GIARPS (GIANO-B + HARPS-N) observing mode of the Telescopio Nazionale Galileo to search for He I absorption in the upper atmospheres of five close-in giant planets hosted by the K and M dwarf stars of our sample, namely WASP-69 b, WASP-107 b, HAT-P-11 b, GJ 436 b, and GJ 3470 b. Methods: We focused our analysis on the nIR He I triplet, performing high-resolution transmission spectroscopy by comparing the in-transit and out-of-transit observations. In instances where nightly variability in the He I absorption signal was identified, we investigated the potential influence of stellar magnetic activity on the planetary absorption signal by searching for variations in the Hα transmission spectrum. Results: We spectrally resolve the He I triplet and confirm the published detections for WASP-69 b (3.91 ± 0.22%, 17.6σ), WASP-107 b (8.17−0.76+0.80%, 10.5σ), HAT-P-11 b (1.36 ± 0.17%, 8.0σ), and GJ 3470 b (1.75−0.36+0.39%, 4.7σ). We do not find evidence of extra absorption for GJ 436 b. We observe night-to-night variations in the He I absorption signal for WASP-69 b, associated with variability in Hα, which likely indicates the influence of pseudo-signals related to stellar activity. Additionally, we find that the He I signal of GJ 3470 b originates from a single transit observation, thereby corroborating the discrepancies found in the existing literature. An inspection of the Hα line reveals an absorption signal during the same transit event. Conclusions: By combining our findings with previous analyses of GIANO-B He I measurements of planets orbiting K dwarfs, we explore potential trends with planetary and stellar parameters that are thought to affect the absorption of metastable He I. Our analysis is unable to identify clear patterns, thus emphasising the necessity for additional measurements and the exploration of potential additional parameters that may be important in controlling He I absorption in planetary upper atmospheres

Responding to globalisation: The case of elite artistic gymnastics in China

This paper was accepted for publication in the journal International Review for the Sociology of Sport and the definitive published version is available at https://doi.org/10.1177/1012690217730679.This article explores a non-Western nation’s responses to globalisation through an in-depth analysis of elite artistic gymnastics in China over a lengthy time span. The concept of globalisation and patterns of ‘reach’ and ‘response’ act as the heuristic devices underpinning the analysis. Data were collected from a range of documents and fromand six semi-structured interviews. The trajectory of Chinese elite artistic gymnastics’ responses to globalisation can be characterised as a passive response in the 1950s, a participative response in the first half of the 1960s, a conflictual response from 1966 to the early 1970s, a participative response from the early 1970s to the 2012 Olympic Games, and a passive response, once again, during the Rio Olympiad (post-London 2012). In this way, a nation’s responses to globalisation are seen as dynamic rather than rigid or static. The ever-expanding reach of the international federation-led global system fundamentally demarcates the activities of member states. However, any nation-state has a degree of autonomy when responding to globalisation and in deciding the detailed pathways whereby to pursue success within this system, although in extreme cases, a nation-state can choose to resist this globalising context, largely depending on a government’s attitude towards globalisation and the value the government attaches to it

ANALISIS PENGARUH NPL, LDR, SENSITIVITAS KREDIT ATAS PERUBAHAN BI RATE DAN INFLASI TERHADAP NIM DENGAN STATUS KEPEMILIKAN DAN UKURAN BANK SEBAGAI VARIABEL KONTROL

This study is performed to test the effect of NPL, LDR, sensitivity of BI rate, and sensitivity of inflationtoward NIMwith ownership status and size as control variables. The objective to analyze the effect of the bank financial ratios performance (NPL, LDR, sensitivity of BI rate, and sensitivity of inflation) toward NIM with ownership status and size as control variablesin banking industry over period 2011-2013. Sampling technique used here is pusposive sampling. The data wastakenOtoritasJasaKeuangan (OJK). It is gained sample amount of 95 data. The analysis technique used here is multiple regression with the least square difference and hypothesis test using t-statistic to examine partial regression coefficient and f-statistic to examine the mean of mutual effect with level of significance 5%. In addition, classical assumption is also performed including normality test, multicolinearity test, heteroscedasticity test and autocorrelation test. The result showsNPL and LDRto have influence toward NIM at level of significance less than 5%, and sensitivity of BI rateand inflation have no influence toward NIM at level of significance more than 5%

English

Three new guaianolides 11-H-13-rnethylsulfonylgrosheirnin 5 (Grosulfeirnin), 8-deoxy-11, 13-dihydroxygrosheimin 7 and 8-deoxy-11-hydroxy-13-chlorogrosheimin 8 have been isolated from the leaves of Cynara scolymus L. Besides, 8-epigrosheirnin 9 has been isolated for the ftrst time frorn this source. The structures were deterrnined by spectroscopical rnethods and by chernical correlations