Is the Bucharest Convention on the protection of the Black Sea against pollution still a matter of general concern? Has it reached its purpose?

If one takes into account the challenges that the Black Sea faces - eutrophication, chemical pollution, threats to biodiversity and dramatic reduction of living marine resources, mainly due to the inappropriate conservation measures regarding the fishing areas at the maritime basis - the question that arises is whether we can assert -after 20 years of application - that the Bucharest Convention on the protection of the Black Sea against pollution is still useful, that it has reached its purpose. The question is favored by the fact that the European Union seems more and more concerned with cooperation in the area, which also results from the former Communication of the Commission "Black Sea Synergy - a New Regional Cooperation Initiative", COM(2007)160.chemical pollution, threats to biodiversity

Prospectives

Tiré de: Prospectives, vol. 13, no 1, février 1977.Titre de l'écran-titre (visionné le 24 janv. 2013

Prospectives

Tiré de: Prospectives, vol. 14, no 1-2, février/avril 1978.Titre de l'écran-titre (visionné le 24 janv. 2013

Prospectives

Tiré de: Prospectives, vol. 22, no 1, février 1986.Titre de l'écran-titre (visionné le 24 janv. 2013

Prospectives

Tiré de: Prospectives, vol. 18, no 1/2, février/avril 1982Titre de l'écran-titre (visionné le 24 janv. 2013

Mentalidade ilustrada na colonização portuguesa: Luís dos Santos Vilhena

Quem desejar compreender o mundo das idéias no Brasil no final do século XVIII, não deve ter a ilusão de querer encontrar apenas idéias revolucionárias e idéias ajustadas ao sistema colonial, idéias de Revolução e idéias de quietação

Elucidation of intracellular recycling pathways leading to exocytosis of the Fc receptor, FcRn, by using multifocal plane microscopy

The intracellular events on the recycling pathway that lead from sorting endosomes to exocytosis at the plasma membrane are central to cellular function. However, despite intensive study, these processes are poorly characterized in spatial and dynamic terms. The primary reason for this is that, to date, it has not been possible to visualize rapidly moving intracellular compartments in three dimensions in cells. Here, we use a recently developed imaging setup in which multiple planes can be simultaneously imaged within the cell in conjunction with visualization of the plasma membrane plane by using total internal reflection fluorescence microscopy. This has allowed us to track and characterize intracellular events on the recycling pathway that lead to exocytosis of the MHC Class I-related receptor, FcRn. We observe both direct delivery of tubular and vesicular transport containers (TCs) from sorting endosomes to exocytic sites at the plasma membrane, and indirect pathways in which TCs that are not in proximity to sorting endosomes undergo exocytosis. TCs can also interact with different sorting endosomes before exocytosis. Our data provide insight into the intracellular events that precede exocytic fusion