Mechanoregulation of bone remodeling and healing as inspiration for self-repair in materials

The material bone has attracted the attention of material scientists due to its fracture resistance and ability to self-repair. A mechanoregulated exchange of damaged bone using newly synthesized material avoids the accumulation of fatigue damage. This remodeling process is also the basis for structural adaptation to common loading conditions, thereby reducing the probability of material failure. In the case of fracture, an initial step of tissue formation is followed by a mechanobiological controlled restoration of the pre-fracture state. The present perspective focuses on these mechanobiological aspects of bone remodeling and healing. Specifically, the role of the control function is considered, which describes mechanoregulation as a link between mechanical stimulation and the local response of the material through changes in structure or material properties. Mechanical forces propagate over large distances leading to a complex non-local feedback between mechanical stimulation and material response. To better understand such phenomena, computer models are often employed. As expected from control theory, negative and positive feedback loops lead to entirely different time evolutions, corresponding to stable and unstable states of the material system. After some background information about bone remodeling and healing, we describe a few representative models, the corresponding control functions, and their consequences. The results are then discussed with respect to the potential design of synthetic materials with specific self-repair properties

Spin blockade in ground state resonance of a quantum dot

We present measurements on spin blockade in a laterally integrated quantum dot. The dot is tuned into the regime of strong Coulomb blockade, confining ~ 50 electrons. At certain electronic states we find an additional mechanism suppressing electron transport. This we identify as spin blockade at zero bias, possibly accompanied by a change in orbital momentum in subsequent dot ground states. We support this by probing the bias, magnetic field and temperature dependence of the transport spectrum. Weak violation of the blockade is modelled by detailed calculations of non-linear transport taking into account forbidden transitions.Comment: 4 pages, 4 figure

Microwave spectroscopy on a double quantum dot with an on-chip Josephson oscillator

We present measurements on microwave spectroscopy on a double quantum dot with an on-chip microwave source. The quantum dots are realized in the two-dimensional electron gas of an AlGaAs/GaAs heterostructure and are weakly coupled in series by a tunnelling barrier forming an 'ionic' molecular state. We employ a Josephson oscillator formed by a long Nb/Al-AlO$_x$/Nb junction as a microwave source. We find photon-assisted tunnelling sidebands induced by the Josephson oscillator, and compare the results with those obtained using an externally operated microwave source.Comment: 6 pages, 4 figure

An electrostatically defined serial triple quantum dot charged with few electrons

A serial triple quantum dot (TQD) electrostatically defined in a GaAs/AlGaAs heterostructure is characterized by using a nearby quantum point contact as charge detector. Ground state stability diagrams demonstrate control in the regime of few electrons charging the TQD. An electrostatic model is developed to determine the ground state charge configurations of the TQD. Numerical calculations are compared with experimental results. In addition, the tunneling conductance through all three quantum dots in series is studied. Quantum cellular automata processes are identified, which are where charge reconfiguration between two dots occurs in response to the addition of an electron in the third dot.Comment: 12 pages, 9 figure

Frictional Drag Between Coupled 2D Hole Gases in GaAs/AlGaAs Heterostructures

We report on the first measurements of the drag effect between coupled 2D-hole gases. We investigate the coupling by changing the carrier densities in the quantum wells, the widths of the barriers between the gases and the perpendicular magnetic field. From the data we are able to attribute the frictional drag to phonon coupling, because the non-parabolicity allows to tune the Fermi wavevector and the Fermi velocity separately and, thereby, to distinguish between phonon- and plasmon-dominated coupling.Comment: 10 pages, 5 figure

Evidence of breakdown of the spin symmetry in diluted 2D electron gases

Recent claims of an experimental demonstration of spontaneous spin polarisation in dilute electron gases \cite{young99} revived long standing theoretical discussions \cite{ceper99,bloch}. In two dimensions, the stabilisation of a ferromagnetic fluid might be hindered by the occurrence of the metal-insulator transition at low densities \cite{abra79}. To circumvent localisation in the two-dimensional electron gas (2DEG) we investigated the low populated second electron subband, where the disorder potential is mainly screened by the high density of the first subband. This letter reports on the breakdown of the spin symmetry in a 2DEG, revealed by the abrupt enhancement of the exchange and correlation terms of the Coulomb interaction, as determined from the energies of the collective charge and spin excitations. Inelastic light scattering experiments and calculations within the time-dependent local spin-density approximation give strong evidence for the existence of a ferromagnetic ground state in the diluted regime.Comment: 4 pages, 4 figures, Revte

Direct control of the tunnel splitting in a one-electron double quantum dot

Quasi-static transport measurements are employed on a laterally defined tunnel-coupled double quantum dot. A nearby quantum point contact allows us to track the charge as added to the device. If charged with only up to one electron, the low-energy spectrum of the double quantum dot is characterized by its quantum mechanical interdot tunnel splitting. We directly measure its magnitude by utilizing particular anticrossing features in the stability diagram at finite source-drain bias. By modification of gate voltages defining the confinement potential as well as by variation of a perpendicular magnetic field we demonstrate the tunability of the coherent tunnel coupling.Comment: High resolution pdf file available at http://www2.nano.physik.uni-muenchen.de/~huettel/research/anticrossing.pd

Determination of MSSM Parameters from LHC and ILC Observables in a Global Fit

We present the results of a realistic global fit of the Lagrangian parameters of the Minimal Supersymmetric Standard Model assuming universality for the first and second generation and real parameters. No assumptions on the SUSY breaking mechanism are made. The fit is performed using the precision of future mass measurements of superpartners at the LHC and mass and polarized topological cross-section measurements at the ILC. Higher order radiative corrections are accounted for whereever possible to date. Results are obtained for a modified SPS1a MSSM benchmark scenario but they were checked not to depend critically on this assumption. Exploiting a simulated annealing algorithm, a stable result is obtained without any a priori assumptions on the values of the fit parameters. Most of the Lagrangian parameters can be extracted at the percent level or better if theoretical uncertainties are neglected. Neither LHC nor ILC measurements alone will be sufficient to obtain a stable result. The effects of theoretical uncertainties arising from unknown higher-order corrections and parametric uncertainties are examined qualitatively. They appear to be relevant and the result motivates further precision calculations. The obtained parameters at the electroweak scale are used for a fit of the parameters at high energy scales within the bottom-up approach. In this way regularities at these scales are explored and the underlying model can be determined with hardly any theoretical bias. Fits of high-scale parameters to combined LHC+ILC measurements within the mSUGRA framework reveal that even tiny distortions in the low-energy mass spectrum already lead to inacceptable chi^2 values. This does not hold for ``LHC only'' inputs.Comment: 25 pages, 5 figure

Sfermion Pair Production at μ+μ−\mu^+ \mu^- Colliders

We discuss pair production of stops, sbottoms, staus and tau--sneutrinos at a $\mu^+ \mu^-$ collider. We present the formulae for the production cross sections and perform a detailed numerical analysis within the Minimal Supersymmetric Standard Model. In particular, we consider sfermion production near $\sqrt{s} = m_{H^0}$ and $\sqrt{s} = m_{A^0}$.Comment: 21 pages, Latex, uses Revtex (included), 8 figures (included as PS-files

On the two-loop Yukawa corrections to the MSSM Higgs boson masses at large tan(beta)

We complete the effective potential calculation of the two-loop, top/bottom Yukawa corrections to the Higgs boson masses in the Minimal Supersymmetric Standard Model, by computing the O(at^2 + at*ab + ab^2) contributions for arbitrary values of the bottom Yukawa coupling. We also compute the corrections to the minimization conditions of the effective potential at the same perturbative order. Our results extend the existing O(at^2) calculation, and are relevant in regions of the parameter space corresponding to tan(beta) >> 1. We extend to the Yukawa corrections a convenient renormalization scheme, previously proposed for the O(ab*as) corrections, that avoids unphysically large threshold effects associated with the bottom mass and absorbs the bulk of the corrections into the one-loop expression. For large values of tan(beta), the new contributions can account for a variation of several GeV in the lightest Higgs boson mass.Comment: 19 pages, 4 eps figures. Some formulae corrected in the Appendi