Advanced rechargeable sodium batteries with novel cathodes

Various high energy density rechargeable batteries are being considered for future space applications. Of these, the sodium sulfur battery is one of the leading candidates. The primary advantage is the high energy density (760 Wh/kg theoretical). Energy densities in excess of 180 Wh/kg have been realized in practical batteries. More recently, cathodes other than sulfur are being evaluated. Researchers at JPL are evaluating various new cathode materials for use in high energy density sodium batteries for advanced space applications. The approach is to carry out basic electrochemical studies of these materials in a sodium cell configuration in order to understand their fundamental behaviors. Thus far studies have focused on alternate metal chlorides such as CuCl2 and organic cathode materials such as tetracyanoethylene (TCNE)

Copper chloride cathode for a secondary battery

Higher energy and power densities are achieved in a secondary battery based on molten sodium and a solid, ceramic separator such as a beta alumina and a molten catholyte such as sodium tetrachloroaluminate and a copper chloride cathode. The higher cell voltage of copper chloride provides higher energy densities and the higher power density results from increased conductivity resulting from formation of copper as discharge proceeds

Organic cathode for a secondary battery

A liquid catholyte for a battery based on liquid metal such as sodium anode and a solid, ceramic separator such as beta alumina (BASE) comprises a mixture of a Group I-III metal salt such as sodium tetrachloroaluminate and a minor amount of an organic carbonitrile depolarizer having at least one adjacent ethylenic band such as 1 to 40 percent by weight of tetracyanoethylene. The tetracyanoethylene forms an adduct with the molten metal salt

Cluster of legionnaires’ disease in an Italian prison

Background: Legionella pneumophila (Lp) is the most common etiologic agent causing Legionnaires’ Disease (LD). Water systems offer the best growth conditions for Lp and support its spread by producing aerosols. From 2015 to 2017, the Regional Reference Laboratory of Clinical and Environmental Surveillance of Legionellosis of Palermo monitored the presence of Lp in nine prisons in Western Sicily. During this investigation, we compared Lp isolates from environmental samples in a prison located in Palermo with isolates from two prisoners in the same prison. Methods: We collected 93 water samples from nine Sicilian prisons and the bronchoalveolar lavages (BALs) of two prisoners considered cases of LD. These samples were processed following the procedures described in the Italian Guidelines for the Prevention and Control of Legionellosis of 2015. Then, genotyping was performed on 19 Lp colonies (17 from water samples and 2 from clinical samples) using the Sequence-Based Typing (SBT) method, according to European Study Group for Legionella Infections (ESGLI) protocols. Results: Lp serogroup (sg) 6 was the most prevalent serogroup isolated from the prisons analyzed (40%), followed by Lp sg 1 (16%). Most of all, in four penitentiary institutions, we detected a high concentration of Lp >104 Colony Forming Unit/Liter (CFU/L). The environmental molecular investigation found the following Sequence Types (STs) in Lp sg 6: ST 93, ST 292, ST 461, ST 728, ST 1317 and ST 1362, while most of the isolates in sg 1 belonged to ST 1. We also found a new ST that has since been assigned the number 2451 in the ESGLI-SBT database. From the several Lp sg 1 colonies isolated from the two BALs, we identified ST 2451. Conclusions: In this article, we described the results obtained from environmental and epidemiological investigations of Lp isolated from prisons in Western Sicily. Furthermore, we reported the first cluster of Legionnaires’ in an Italian prison and the molecular typing of Lp sg 1 from one prison’s water system and two BALs, identified the source of the contamination, and discovered a new ST

Do Patent Trolls Exist? Examining the Economic Impact of Non-Practicing Entities and Patent Infringement Litigation on Innovation

Thesis advisor: Julie MortimerNon-practicing entities (NPEs) – firms that do not produce goods or services but license to and sue other companies with portfolios of patents – have drastically increased patent infringement litigation since 2006. Over the same period, the USPTO has granted an increasing amount of patents, indicating that American innovation has strengthened by one measure. This paper finds fault with equating patents granted to innovation and develops a new metric of innovation – the ratio of a firm’s intangible to total assets. Through empirical analysis this study concludes that lawsuits initiated by NPEs between 2006 and 2011 do not affect the rate of American innovation. However, this study also finds that NPEs inflict at least a $567 million innovation cost to the top twenty-five most litigated against firms in the United States. This cost represents money that could be allocated towards research and development or investment, but it is not a dead-weight loss – it is the cost associated with firms’ growth measured in inflation-adjusted total assets. Ultimately, this study highlights the need for continued research into the impact of NPEs on the American economy but provides empirical evidence that the patent troll classification is unwarranted.Thesis (BA) — Boston College, 2012.Submitted to: Boston College. College of Arts and Sciences.Discipline: International Studies Honors Program.Discipline: Economics Honors Program.Discipline: International Studies

THYROSIM App for Education and Research Predicts Potential Health Risks of Over-the-Counter Thyroid Supplements

Background: Computer simulation tools for education and research are making increasingly effective use of the Internet and personal devices. To facilitate these activities in endocrinology and metabolism, a mechanistically based simulator of human thyroid hormone and thyrotropin (TSH) regulation dynamics was developed and further validated, and it was implemented as a facile and freely accessible web-based and personal device application: the THYROSIM app. This study elucidates and demonstrates its utility in a research context by exploring key physiological effects of over-the-counter thyroid supplements. Methods: THYROSIM has a simple and intuitive user interface for teaching and conducting simulated ?what-if? experiments. User-selectable ?experimental? test-input dosages (oral, intravenous pulses, intravenous infusions) are represented by animated graphical icons integrated with a cartoon of the hypothalamic?pituitary?thyroid axis. Simulations of familiar triiodothyronine (T3), thyroxine (T4), and TSH temporal dynamic responses to these exogenous stimuli are reported graphically, along with normal ranges on the same single interface page; and multiple sets of simulated experimental results are superimposable to facilitate comparative analyses. Results and Conclusions: This study shows that THYROSIM accurately reproduces a wide range of published clinical study data reporting hormonal kinetic responses to large and small oral hormone challenges. Simulation examples of partial thyroidectomies and malabsorption illustrate typical usage by optionally changing thyroid gland secretion and/or gut absorption rates?expressed as percentages of normal?as well as additions of oral hormone dosing, all directly on the interface, and visualizing the kinetic responses to these challenges. Classroom and patient education usage?with public health implications?is illustrated by predictive simulated responses to nonprescription thyroid health supplements analyzed previously for T3 and T4 content. Notably, it was found that T3 in supplements has potentially more serious pathophysiological effects than does T4?concomitant with low-normal TSH levels. Some preparations contain enough T3 to generate thyrotoxic conditions, with supernormal serum T3-spiking and subnormal serum T4 and TSH levels and, in some cases, with normal or low-normal range TSH levels due to thyroidal axis negative feedback. These results suggest that appropriate regulation of these products is needed.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/140268/1/thy.2015.0373.pd

Spatial Interpolants

We propose Splinter, a new technique for proving properties of heap-manipulating programs that marries (1) a new separation logic-based analysis for heap reasoning with (2) an interpolation-based technique for refining heap-shape invariants with data invariants. Splinter is property directed, precise, and produces counterexample traces when a property does not hold. Using the novel notion of spatial interpolants modulo theories, Splinter can infer complex invariants over general recursive predicates, e.g., of the form all elements in a linked list are even or a binary tree is sorted. Furthermore, we treat interpolation as a black box, which gives us the freedom to encode data manipulation in any suitable theory for a given program (e.g., bit vectors, arrays, or linear arithmetic), so that our technique immediately benefits from any future advances in SMT solving and interpolation.Comment: Short version published in ESOP 201

Signatures of Galaxy-Cluster Interactions: Spiral Galaxy Rotation Curve Asymmetry, Shape, and Extent

The environmental dependencies of the characteristics of spiral galaxy rotation curves are studied in this work. We use our large, homogeneously collected sample of 510 cluster spiral galaxy rotation curves to test the claim that the shape of a galaxy's rotation curve strongly depends on its location within the cluster, and thus presumably on the strength of the local intracluster medium and on the frequency and strength of tidal interactions with the cluster and cluster galaxies. Our data do not corroborate such a scenario, consistent with the fact that Tully-Fisher residuals are independent of galaxy location within the cluster; while the average late-type spiral galaxy shows more rise in the outer parts of its rotation curve than does the typical early-type spiral galaxy, there is no apparent trend for either subset with cluster environment. We also investigate as a function of cluster environment rotation curve asymmetry and the radial distribution of H II region tracers within galactic disks. Mild trends with projected cluster-centric distance are observed: (i) the (normalized) radial extent of optical line emission averaged over all spiral galaxy types shows a 4%+/-2% increase per Mpc of galaxy-cluster core separation, and (ii) rotation curve asymmetry falls by a factor of two between the inner and outer cluster for early-type spirals (a negligible decrease is found for late-type spirals). Such trends are consistent with spiral disk perturbations or even the stripping of the diffuse, outermost gaseous regions within the disks as galaxies pass through the dense cluster cores.Comment: 17 pages; to appear in the April 2001 Astronomical Journa

Chandra Studies of the X-ray Point Source Luminosity Functions of M31

Three different M31 disk fields, spanning a range of stellar populations, were observed by Chandra. We report the X-ray point source luminosity function (LF) of each region, and the LF of M31's globular clusters, and compare these with each other and with the LF of the galaxy's bulge. To interpret the results we also consider tracers of the stellar population, such as OB associations and supernova remnants. We find differences in the LFs among the fields, but cannot definitively relate them to the stellar content of the fields. We find that stellar population information, average and maximum source luminosities, X-ray source densities, and slopes of the LF are useful in combination.Comment: 7 pages, 3 figures, accepted for publication in ApJ. Higher-resolution figures available on reques