Near-infrared Observations of Be/X-ray Binary Pulsar A0535+262

We present results obtained from an extensive near-infrared spectroscopic and photometric observations of the Be/X-ray binary A0535+262/HDE 245770 at different phases of its ~111 day orbital period. This observation campaign is a part of the monitoring programme of selective Be/X-ray binary systems aimed at understanding the X-ray and near-IR properties at different orbital phases, especially during the periastron passage of the neutron star. The near-IR observations were carried out using the 1.2 m telescope at Mt. Abu IR observatory. Though the source was relatively faint for spectroscopic observations with 1.2 m telescope, we monitored the source during the 2011 February--March giant outburst to primarily investigate whether any drastic changes in the near-IR JHK spectra take place at the periastron passage. Changes of such a striking nature were expected to be detectable in our spectra. Photometric observations of the Be star show a gradual and systematic fading in the JHK light curves since the onset of the X-ray outburst that could suggest a mild evacuation/truncation of the circumstellar disc of the Be companion. Near-IR spectroscopy of the object shows that the JHK spectra are dominated by the emission lines of hydrogen Brackett and Paschen series and HeI lines at 1.0830, 1.7002 and 2.0585 micron. The presence of all hydrogen emission lines in the JHK spectra, along with the absence of any significant change in the continuum of the Be companion during X-ray quiescent and X-ray outburst phases suggest that the near-IR line emitting regions of the disc are not significantly affected during the X-ray outburst.Comment: 10 Pages, 5 Figures, Accepted for publication in Res. in Astronomy and Astrophysic

Design of dimensional model for clinical data storage and analysis

Current research in the field of Life and Medical Sciences is generating chunk of data on daily basis. It has thus become a necessity to find solutions for efficient storage of this data, trying to correlate and extract knowledge from it. Clinical data generated in Hospitals, Clinics & Diagnostics centers is falling under a similar paradigm. Patient’s records in various hospitals are increasing at an exponential rate, thus adding to the problem of data management and storage. Major problem being faced corresponding to storage, is the varied dimensionality of the data, ranging from images to numerical form. Therefore there is a need for development of efficient data model which can handle this multi-dimensionality data issue and store the data with historical aspect. For the stated problem lying in façade of clinical informatics we propose a clinical dimensional model design which can be used for development of a clinical data mart. The model has been designed keeping in consideration temporal storage of patient's data with respect to all possible clinical parameters which can include both textual and image based data. Availability of said data for each patient can be then used for application of data mining techniques for finding the correlation of all the parameters at the level of individual and population

Liquid-like behaviour of gold nanowire bridges

A combination of Focused Ion Beam (FIB) and Reactive Ion Etch (RIE) was used to fabricate free standing gold nanowire bridges with radii of 30 nm and below. These were subjected to point loading to failure at their mid-points using an Atomic Force Microscope (AFM), providing strength and deformation data. The results demonstrate a dimensionally dependent transition from conventional solid metallic properties to liquid-like behaviour including the unexpected reformation of a fractured bridge. The work reveals mechanical and materials properties of nanowires which could have significant impact on nanofabrication processes and nanotechnology devices such as Nano Electro Mechanical Systems (NEMS)

Association rule mining based study for identification of clinical parameters akin to occurrence of brain tumor

Healthcare sector is generating a large amount of information corresponding to diagnosis, disease identification and treatment of an individual. Mining knowledge and providing scientific decision-making for the diagnosis & treatment of disease from the clinical dataset is therefore increasingly becoming necessary. Aim of this study was to assess the applicability of knowledge discovery in brain tumor data warehouse, applying data mining techniques for investigation of clinical parameters that can be associated with occurrence of brain tumor. In this study, a brain tumor warehouse was developed comprising of clinical data for 550 patients. Apriori association rule algorithm was applied to discover associative rules among the clinical parameters. The rules discovered in the study suggests - high values of Creatinine, Blood Urea Nitrogen (BUN), SGOT & SGPT to be directly associated with tumor occurrence for patients in the primary stage with atleast 85% confidence and more than 50% support. A normalized regression model is proposed based on these parameters along with Haemoglobin content, Alkaline Phosphatase and Serum Bilirubin for prediction of occurrence of STATE (brain tumor) as 0 (absent) or 1 (present). The results indicate that the methodology followed will be of good value for the diagnostic procedure of brain tumor, especially when large data volumes are involved and screening based on discovered parameters would allow clinicians to detect tumors at an early stage of development

Random access quantum information processors

Qubit connectivity is an important property of a quantum processor, with an ideal processor having random access -- the ability of arbitrary qubit pairs to interact directly. Here, we implement a random access superconducting quantum information processor, demonstrating universal operations on a nine-bit quantum memory, with a single transmon serving as the central processor. The quantum memory uses the eigenmodes of a linear array of coupled superconducting resonators. The memory bits are superpositions of vacuum and single-photon states, controlled by a single superconducting transmon coupled to the edge of the array. We selectively stimulate single-photon vacuum Rabi oscillations between the transmon and individual eigenmodes through parametric flux modulation of the transmon frequency, producing sidebands resonant with the modes. Utilizing these oscillations for state transfer, we perform a universal set of single- and two-qubit gates between arbitrary pairs of modes, using only the charge and flux bias of the transmon. Further, we prepare multimode entangled Bell and GHZ states of arbitrary modes. The fast and flexible control, achieved with efficient use of cryogenic resources and control electronics, in a scalable architecture compatible with state-of-the-art quantum memories is promising for quantum computation and simulation.Comment: 7 pages, 5 figures, supplementary information ancillary file, 21 page

Mode of interaction of calcium oxalate crystal with human phosphate cytidylyltransferase 1: a novel inhibitor purified from human renal stone matrix

Nephrolithiasis is a common clinical disorder, and calcium oxalate (CaOx) is the principal crystalline component in approximately 75% of all renal stones. It is widely believed that proteins act as inhibitors of crystal growth and aggregation. Acidic amino acids present in these proteins play a significant role in the inhibition process. In this study, interaction of cal-cium oxalate with human phosphate cytidylyltrans-ferase 1(CCT), a novel calcium oxalate crystal growth inhibitor purified from human renal stone matrix has been elucidated in silico and involvement of acidic amino acids in the same. As only sequence of CCT is available, henceforth its 3-D structure was modeled via Homology modeling using Prime module of Schrodinger package. Molecular dynamic simulation of modeled protein with solvation was done by mac-romodel (Schrodinger). The quality of modeled pro-tein was validated by JCSG protein structure valida-tion (PROCHECK & ERRAT) server. To analyze the interaction of modeled protein CCT with calcium oxalate along with role played by acidic amino acids, ‘Docking simulation’ was done using MOE–Dock. Interaction between calcium oxalate and CCT was also studied by substituting acidic amino acid in the active sites of the protein with neutral and positively charged amino acids. The in silico analysis showed the bond formation between the acidic amino acids and calcium atom, which was further substantiated when substitution of these acidic amino acids with alanine, glycine, lysine, arginine and histidine com-pletely diminished the interaction with calcium ox-alate

The Non-Perturbative N=2{\cal N} = 2 SUSY Yang-Mills Theory from Semiclassical Absorption of Supergravity by Wrapped D Branes

The imaginary part of the two point functions of the superconformal anomalous currents are extracted from the cross-sections of semiclassical absorption of dilaton, RR-2 form and gravitino by the wrapped D5 branes. From the central terms of the two point functions anomalous Ward identity is established which relates the exact pre-potential of the ${\cal N}=2$ SUSY Yang-Mills theory with the vacuum expectation value of the anomaly multiplet. From the Ward identity, WDVV (Witten-Dijkgraaf-Verlinde-Verlinde) equation can be derived which is solved for the exact pre-potential.Comment: 11 pages, late

Management of red rust thrips, Chaetanophothripssignipennis (Bagnall) in banana

The commercial value of banana is mainly affected by red rust thrips, Chaetanophothripssignipennis(Bagnall) during fruiting phase at maturity. In this context, the trial was framed at F.R.S., N.A.U., Gandevi under ICAR-AICRP (Fruits) programme. The three years data on efficacy of bio-rational pesticides for management of red rust thrips revealed that bud injection of imidacloprid (0.3 ml/ 500 ml water) @ 1 ml/bud exhibited lowest unblemished fruits up to 8.37% over conventional spraying (20.72%) and bunch sleeving method (42.83%). The comparable results on fruit damage (14.83%) was observed with bud injection of azadirachtin (1%) (5 ml/l water) @ 2 ml/bud over conventional spray. The merit of technology furnished higher no. of unblemished fruits (<10%) and original peel superficial appearance remains impassive under bud injection technique with higher benefit cost ratio with very low dose of pesticide provide financial profit to growers and traders. Besides, imidacloprid residue was not detected in harvested fruits and there is no other technology available to remove this malady of banan