Foam-machining tool with eddy-current transducer

Three-cutter machining system for foam-covered tanks incorporates eddy-current sensor. Sensor feeds signal to numerical controller which programs rotational and vertical axes of sensor travel, enabling cutterhead to profile around tank protrusions

Endolithic trace fossils in Ordovician-Silurian corais and stromatoporoids, Anticosti Island, eastern Canada

Bioerosion was a significant process in the destruction of reef-building skeletons in early and mid-Paleozoic marine carbonate settings. Ordovician-Silurian corals and stromatoporoids from Anticosti Island show a limited diversity of macroborings, dominated by Trypanites, but also includes rare occurrences of an Ordovician bivalve boring (Petroxestes pera), described here for the first time in Early Silurian stromatoporoids. Two problematic embedment structures, one containing lingulid brachiopods, resemble borings but did not contribute to bioerosion. The distribution of the embedment structures and Petroxestes pera are restricted by facies and skeletal substrate. Trypanites is relatively nonspecific, occurring in reef and off-reef facies and in most skeletal substrates; it does not appear to have been affected by the Late Ordovician mass extinction

500 TeV gamma rays from Hercules X-1

A signal (chance probability = .0002) with the 1.24 s period of Hercules X-1 has been observed using the Utah Fly's Eye. The signal's relatively long period and high shower energy conflict with some popular models of particle acceleration by pulsars. Optical and X-ray data suggest a picture in which energetic particles produce multi-TeV gamma rays by collisions with Hercules X-1's accretion disk

Drug-induced Sleep Endoscopy:Are there Predictors for Failure of Oral Appliance Treatment?

Introduction In the literature, evidence is lacking on the predictive value of drug-induced sleep endoscopy (DISE) for oral appliance treatment (OAT). Objectives The aim of the present study is to evaluate whether DISE with concomitant mandibular advancement maneuver can predict failure of OAT. Methods An observational retrospective study including patients diagnosed with obstructive sleep apnea (OSA) who previously received OAT. Results of DISE were analyzed in a group with documented OAT failure (apnea-hypopnea index [AHI] > 10 events/hour or  50% reduction). The upper airway was assessed using the velum, oropharynx, tongue base, epiglottis (VOTE) classification. Additionally, a mandibular advancement maneuver, manually protruding the mandible by performing a jaw thrust, was performed to mimic the effect of OAT. Results The present study included 50 patients with OAT failure and 20 patients with OAT benefit. A subgroup analysis of patients with OAT failure and an AHI < 30 events/hour included 26 patients. In the OAT failure group, 74% had a negative jaw thrust maneuver. In the subgroup with an AHI < 30 events/hour, 76.9% had a negative jaw thrust maneuver. In the OAT benefit group, 25% had a negative jaw thrust maneuver (p < 0.001). Conclusions A negative jaw thrust maneuver during DISE can be a valuable predictor for OAT failure, independent of AHI. Drug-induced sleep endoscopy should be considered as a diagnostic evaluation tool before starting OAT

Older adults experiences of rehabilitation in acute health care

Rehabilitation is a key component of nursing and allied healthcare professionals’ roles in most health and social care settings. This paper reports on stage 2 of an action research project to ascertain older adult's experience of rehabilitation. Twenty postdischarge interviews were conducted and the interview transcripts were analysed using thematic content analysis. All older adults discharged from an acute older acute rehabilitation ward to their own homes in the community were eligible to participate. The only exclusion criterion was older adults who were thought to be unable to give consent to participate by the nurse in charge and the researcher. Whilst 92 older adults were eligible to participate in this research study, only 20 were interviewed. The findings from this study suggest that older adults valued communication with health professionals but were aware of their time constraints that hindered communication. This study suggests that both nurses and allied health professionals are not actively providing rehabilitative services to promote health and well-being, which contradicts the focus of active ageing. Furthermore, there was evidence of unmet needs on discharge, and older adults unable to recall the professions that were involved in their interventions and the rationale for therapy input. It is suggested that further research is needed to explore the effectiveness of allied health rehabilitation in the acute setting. This study highlights the need for further research into older adults’ perceptions of the rehabilitation process in the acute setting

Prediction of obstructive sleep apnea:comparative performance of three screening instruments on the apnea-hypopnea index and the oxygen desaturation index

PURPOSE: To evaluate the performance of the NoSAS (neck, obesity, snoring, age, sex) score, the STOP-Bang (snoring, tiredness, observed apneas, blood pressure, body mass index, age, neck circumference, gender) questionnaire, and the Epworth sleepiness score (ESS) as a screening tool for obstructive sleep apnea (OSA) severity based on the apnea-hypopnea index (AHI) and the oxygen desaturation index (ODI). METHODS: Data from 235 patients who were monitored by ambulant polysomnography (PSG) were retrospectively analyzed. OSA severity was classified based on the AHI; similar classification categories were made based on the ODI. Discrimination was assessed by the area under the curve (AUC), while predictive parameters were calculated by four-grid contingency tables. RESULTS: The NoSAS score and the STOP-Bang questionnaire were both equally adequate screening tools for the AHI and the ODI with AUC ranging from 0.695 to 0.767 and 0.684 to 0.767, respectively. Both questionnaires perform better when used as a continuous variable. The ESS did not show adequate discrimination for screening for OSA (AUC ranging from 0.450 to 0.525). Male gender, age, and BMI proved to be the strongest individual predictors in this cohort. CONCLUSION: This is the first study to evaluate the predictive performance of three different screening instruments with respect to both the AHI and the ODI. This is important, due to increasing evidence that the ODI may have a higher reproducibility in the clinical setting. The NoSAS score and the STOP-Bang questionnaire proved to be equally adequate to predict OSA severity based on both the AHI and the ODI. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s11325-020-02219-6) contains supplementary material, which is available to authorized users

Pion Production from Baked-Alaska Disoriented Chiral Condensate

We study the various stages of the evolution of chiral condensates disoriented via the ``baked-alaska'' mechanism, in which the condensates are described as the products of external sources localized on the light cone. Our analysis is based on the classical equations of motion of either the linear or the nonlinear sigma model. We use the associated framework of coherent states and, especially, their source functions to make the connection to the distribution functions for the produced particles. We also compare our classical approach with a mean-field calculation which includes a certain class of quantum corrections.Comment: replaced to correct misspelling of author's nam

Supersymmetric Electroweak Corrections to the Higgs Boson Decays into Chargino or Neutralino Pair

We investigate the supersymmetric electroweak corrections to the decay widths of the CP-odd and the heavy CP-even Higgs bosons into chargino or neutralino pair in the framework of the Minimal Supersymmetric Standard Model. The corrections involve the contributions of the order $O(\alpha_{ew} m_{t(b)}^3/m_W^3)$, $O(\alpha_{ew} m_{t(b)}^2/m_W^2)$ and $O(\alpha_{ew} m_{t(b)}/m_W)$. The detailed calculations of the electroweak corrections to the following decay processes: $A^0/H^0 \to \tilde{\chi}^+_1 \tilde{\chi}^-_1$ and $A^0/H^0 \to \tilde{\chi}^0_2 \tilde{\chi}^0_2$ are presented in this paper. We find that these relative corrections maybe rather large quantitatively, and can exceed 10% in some regions of parameter space. The corrections to the decay $A^0/H^0 \to \tilde{\chi}^0_1 \tilde{\chi}^0_2$ can be obtained analogously, but our results show that they are very small and can be neglected.Comment: 25 pages, 9 figures,accepted by Physical Review

Retinoid metabolism and all-trans retinoic acid-induced growth inhibition in head and neck squamous cell carcinoma cell lines.

Retinoids can reverse potentially premalignant lesions and prevent second primary tumours in patients with head and neck squamous cell carcinoma (HNSCC). Furthermore, it has been reported that acquired resistance to all-trans retinoic acid (RA) in leukaemia is associated with decreased plasma peak levels, probably the result of enhanced retinoid metabolism. The aim of this study was to investigate the metabolism of retinoids and relate this to growth inhibition in HNSCC. Three HNSCC cell lines were selected on the basis of a large variation in the all-trans RA-induced growth inhibition. Cells were exposed to 9.5 nM (radioactive) for 4 and 24 h, and to 1 and 10 microM (nonradioactive) all-trans RA for 4, 24, 48 and 72 h, and medium and cells were analysed for retinoid metabolites. At all concentrations studied, the amount of growth inhibition was proportional to the extent at which all-trans-, 13- and 9-cis RA disappeared from the medium as well as from the cells. This turnover process coincided with the formation of a group of as yet unidentified polar retinoid metabolites. The level of mRNA of cellular RA-binding protein II (CRABP-II), involved in retinoid homeostasis, was inversely proportional to growth inhibition. These findings indicate that for HNSCC retinoid metabolism may be associated with growth inhibition