528 research outputs found
PeP-SCOT a health coaching intervention for people in prisons:the development of the intervention protocol
The effect of seating preferences of the medical students on educational achievement
Background: The seat selection and classroom dynamics may have mutual influence on the student performance and participation in both assigned and random seating arrangement. Purpose: The aim of the study was to understand the influence of seat selection on educational achievement. Methods: The seating positions of the medical students were recorded on an architectural plan during each class session and the means and standard deviations of the students’ locations were calculated in X and Y orientations. The locations of the students in the class were analyzed based on three architectural classifications: interactional zone, distance from the board, and access to the aisles. Final exam scores were used to measure the students’ educational achievement. Results: Our results demonstrate that there is a statistically significant relationship between the student's locations in the class and their attendance and educational achievements. Conclusion: Two factors may effect on educational achievement: student seating in the high interactional zone and minimal changes in seating location. Seating in the high interaction zone was directly associated with higher performance and inversely correlated with the percentage of absences. This observation is consistent with the view that students in the front of the classroom are likely more motivated and interact with the lecturer more than their classmates
Label-free nanometer-resolution imaging of biological architectures through surface enhanced raman scattering
Label free imaging of the chemical environment of biological specimens would readily bridge the supramolecular and the cellular scales, if a chemical fingerprint technique such as Raman scattering can be coupled with super resolution imaging. We demonstrate the possibility of label-free super-resolution Raman imaging, by applying stochastic reconstruction to temporal fluctuations of the surface enhanced Raman scattering (SERS) signal which originate from biomolecular layers on large-area plasmonic surfaces with a high and uniform hot-spot density (>1011/cm2, 20 to 35 nm spacing). A resolution of 20 nm is demonstrated in reconstructed images of self-assembled peptide network and fibrilated lamellipodia of cardiomyocytes. Blink rate density is observed to be proportional to the excitation intensity and at high excitation densities (>10 kW/cm2) blinking is accompanied by molecular breakdown. However, at low powers, simultaneous Raman measurements show that SERS can provide sufficient blink rates required for image reconstruction without completely damaging the chemical structure
Label-Free Nanometer-Resolution Imaging of Biological Architectures through Surface Enhanced Raman Scattering
Label free imaging of the chemical environment of biological specimens would readily bridge the supramolecular and the cellular scales, if a chemical fingerprint technique such as Raman scattering can be coupled with super resolution imaging. We demonst
Is London open? Mediating and ordering cosmopolitanism in crisis
This article analyses cosmopolitan imagination and ambivalent morality at times of urban crisis. It focuses on #LondonIsOpen – the city’s media campaign in response to the nation’s Brexit vote. In this case, cosmopolitanism’s discursive tools – especially the ideals of the Open city and hospitality – are mobilised to summon a range of actors in defence of the city. The article analyses the mediation of cosmopolitanism in a campaign film and in Londoners’ online and offline responses to it. These responses reveal #LondonIsOpen as a compelling example of cosmopolitan imagination, but also of cosmopolitanism’s moral fragility in the neoliberal city. As shown, urban dwellers overwhelmingly embrace the cosmopolitan value of openness. Yet, their visions are divided between neoliberal cosmopolitanism and vernacular cosmopolitanism. By analysing the moral space of mediated cosmopolitanism, I argue that, unlike the nation, representational struggles in the city increasingly take place within, rather than against, cosmopolitanis
Removal of large hydatid cysts with balloon-assisted modification of Dowling’s method: technical report
Nanoengineering hybrid supramolecular multilayered biomaterials using polysaccharides and self-assembling peptide amphiphiles
Developing complex supramolecular biomaterials through highly dynamic and reversible noncovalent interactions has attracted great attention from the scientific community aiming key biomedical and biotechnological applica-tions, including tissue engineering, regenerative medicine, or drug delivery. In this study, the authors report the fabrication of hybrid supramolecular multilayered biomaterials, comprising high-molecular-weight biopolymers and oppositely charged low-molecular-weight peptide amphiphiles (PAs), through combination of self-assembly and electrostatically driven layer-by-layer (LbL) assembly approach. Alginate, an anionic polysaccharide, is used to trigger the self-assembling capability of positively charged PA and formation of 1D nanofiber networks. The LbL technology is further used to fabricate supramolecular multilayered biomaterials by repeating the alternate deposi-tion of both molecules. The fabrication process is monitored by quartz crystal microbalance, revealing that both materials can be successfully combined to conceive stable supramolecular systems. The morphological properties of the systems are studied by advanced microscopy techniques, revealing the nano-structured dimensions and 1D nanofibrous network of the assembly formed by the two molecules. Enhanced C2C12 cell adhesion, proliferation, and differentiation are observed on nanostructures having PA as outermost layer. Such supramolecular biomaterials demonstrate to be innovative matrices for cell culture and hold great potential to be used in the near future as prom-ising biomimetic supramolecular nanoplatforms for practical applications
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