Fractional excitations in cold atomic gases

We study the behavior of excitations in the tilted one-dimensional Bose-Hubbard model. In the phase with broken symmetry, fundamental excitations are domain walls which show fractional statistics. Using perturbation theory, we derive an analytic model for the time evolution of these fractional excitations, and demonstrate the existence of a repulsively bound state above a critical center-of-mass momentum. The validity of the perturbative analysis is confirmed by the use of time-adaptive density-matrix renormalization group simulations. These findings open the path for the experimental detection of fractional particles in cold atomic gases

Ariel - Volume 4 Number 4

Editors David A. Jacoby Eugenia Miller Tom Williams Associate Editors Paul Bialas Terry Burt Michael Leo Gail Tenikat Editor Emeritus and Business Manager Richard J. Bonnano Movie Editor Robert Breckenridge Staff Richard Blutstein Mary F. Buechler Meg Brunt Steve Glinks Len Grasman Alice M. Johnson J.D. Kanofsky Tom Lehman Dave Mayer Bernie Odd

Observations of Lightning on Earth from the Lunar Surface

The NASA Optical Transient Detector (OTD) launched into a 70deg inclination orbit in April 1995 aboard the MicroLab-1 satellite and the Lightning Imaging Sensor (LIS) launched into a 35deg inclination orbit in November 1997 (and still operating today) aboard the Tropical Rainfall Measuring Mission have produced the most comprehensive global observations of lightning activity on Earth. The OTD collected data for 5-yr from an altitude of 740 km while the LIS, in its 10th year of operations, is still collecting data from its current altitude of 402 km. From these altitudes the OTD observes an individual storm within its field of view for approx.3 min and the LIS for approx.90 sec as the satellites orbit the earth. Figures 1-4 show the combined LIS/OTD distribution of lightning for day and night during the Northern Hemisphere warm season from April through August (Fig. 1,2) and the cool season from October through February (Fig. 3,4) as might be observed from the lunar surface (12-h daylight and 12-h nighttime observations). The day and night plots are for the twelve hour periods centered on local noon and midnight. The total viewtime of the global lightning activity is 200 hours or less, depending on latitude (Fig. 5). Most of the observed lightning occurs over the northern hemisphere land areas as reported in previous studies. More lightning activity is seen at the higher northern latitudes during the day. The greatest lightning maxima occurs in the southeastern US, during the day. The corresponding region at night shows much less lightning activity. In contrast, there is a maxima in lightning activity at night over the high Plains area of the U.S. This region had lower lightning rates during the daytime period. During the cold season, the southern hemisphere has significantly more lightning. The maxima in Central Africa is still present, and a secondary maxima is observed in South Africa. In South America, the maxima in Argentina occurs at night in association with large-scale mesoscale convective storm complexes. This is the region on the earth having the greatest frequency of extreme storms with flash rates exceeding 1000 flashes/min. daytime maxima is seen extending from Northern Argentina to Brazil. In the US., the Gulf of Mexico and the Gulf Coast states exhibit a maximum in lightning activity both day and night

Coordinated System Reliability Assessment And Production Cost Simulation In Transmission Planning Of Eastern Interconnection

This paper presents a transmission need analysis for the Eastern Interconnection (EI) using a coordinated technical approach consisting of system reliability assessment (SRA) and production cost simulation (PCS). As North American Transmission Systems are being evolved with increasing levels of renewable energy resources such as wind, solar, storage, biomass, hydro, etc., maintaining grid reliability and managing transmission congestion cost are becoming increasingly challenging. It also poses complexity and challenges in technical and economic planning of the transmission grid. The coordinated SRA and PCS were conducted to assess transmission reliability and congestion for the interconnected grids of the EI in a 10-year planning horizon. The paper discusses new automation tools and models developed for such assessment including case studies showing the applicability of the coordinated methodology and developed models

Subclinical infection of macaques and baboons with a baboon simarterivirus

Simarteriviruses (Arteriviridae: Simarterivirinae) are commonly found at high titers in the blood of African monkeys but do not cause overt disease in these hosts. In contrast, simarteriviruses cause severe disease in Asian macaques upon accidental or experimental transmission. Here, we sought to better understand the host-dependent drivers of simarterivirus pathogenesis by infecting olive baboons (n = 4) and rhesus monkeys (n = 4) with the simarterivirus Southwest baboon virus 1 (SWBV-1). Surprisingly, none of the animals in our study showed signs of disease following SWBV-1 inoculation. Three animals (two rhesus monkeys and one olive baboon) became infected and sustained high levels of SWBV-1 viremia for the duration of the study. The course of SWBV-1 infection was highly predictable: plasma viremia peaked between 1 × 107 and 1 × 108 vRNA copies/mL at 3–10 days post-inoculation, which was followed by a relative nadir and then establishment of a stable set-point between 1 × 106 and 1 × 107 vRNA copies/mL for the remainder of the study (56 days). We characterized cellular and antibody responses to SWBV-1 infection in these animals, demonstrating that macaques and baboons mount similar responses to SWBV-1 infection, yet these responses are ineffective at clearing SWBV-1 infection. SWBV-1 sequencing revealed the accumulation of non-synonymous mutations in a region of the genome that corresponds to an immunodominant epitope in the simarterivirus major envelope glycoprotein GP5, which likely contribute to viral persistence by enabling escape from host antibodies

Disorder-induced magnetic memory: Experiments and theories

Beautiful theories of magnetic hysteresis based on random microscopic disorder have been developed over the past ten years. Our goal was to directly compare these theories with precise experiments. We first developed and then applied coherent x-ray speckle metrology to a series of thin multilayer perpendicular magnetic materials. To directly observe the effects of disorder, we deliberately introduced increasing degrees of disorder into our films. We used coherent x-rays to generate highly speckled magnetic scattering patterns. The apparently random arrangement of the speckles is due to the exact configuration of the magnetic domains in the sample. In effect, each speckle pattern acts as a unique fingerprint for the magnetic domain configuration. Small changes in the domain structure change the speckles, and comparison of the different speckle patterns provides a quantitative determination of how much the domain structure has changed. How is the magnetic domain configuration at one point on the major hysteresis loop related to the configurations at the same point on the loop during subsequent cycles? The microscopic return-point memory(RPM) is partial and imperfect in the disordered samples, and completely absent when the disorder was not present. We found the complementary-point memory(CPM) is also partial and imperfect in the disordered samples and completely absent when the disorder was not present. We found that the RPM is always a little larger than the CPM. We also studied the correlations between the domains within a single ascending or descending loop. We developed new theoretical models that do fit our experiments.Comment: 26 pages, 25 figures, Accepted by Physical Review B 01/25/0

Independent Validation of EarlyR Gene Signature in BIG 1-98: A Randomized, Double-Blind, Phase III Trial Comparing Letrozole and Tamoxifen as Adjuvant Endocrine Therapy for Postmenopausal Women with Hormone Receptor-Positive, Early Breast Cancer

Background EarlyR gene signature in estrogen receptor–positive (ER+) breast cancer is computed from the expression values of ESPL1, SPAG5, MKI67, PLK1, and PGR. EarlyR has been validated in multiple cohorts profiled using microarrays. This study sought to verify the prognostic features of EarlyR in a case-cohort sample from BIG 1–98, a randomized clinical trial of ER+ postmenopausal breast cancer patients treated with adjuvant endocrine therapy (letrozole or tamoxifen). Methods Expression of EarlyR gene signature was estimated by Illumina cDNA-mediated Annealing, Selection, and Ligation assay of RNA from formalin-fixed, paraffin-embedded primary breast cancer tissues in a case-cohort subset of ER+ women (N = 1174; 216 cases of recurrence within 8 years) from BIG 1–98. EarlyR score and prespecified risk strata (≤25 = low, 26–75 = intermediate, >75 = high) were “blindly” computed. Analysis endpoints included distant recurrence–free interval and breast cancer–free interval at 8 years after randomization. Hazard ratios (HRs) and test statistics were estimated with weighted analysis methods. Results The distribution of the EarlyR risk groups was 67% low, 19% intermediate, and 14% high risk in this ER+ cohort. EarlyR was prognostic for distant recurrence–free interval; EarlyR high-risk patients had statistically increased risk of distant recurrence within 8 years (HR = 1.73, 95% confidence interval = 1.14 to 2.64) compared with EarlyR low-risk patients. EarlyR was also prognostic of breast cancer–free interval (HR = 1.74, 95% confidence interval = 1.21 to 2.62). Conclusions This study confirmed the prognostic significance of EarlyR using RNA from formalin-fixed, paraffin-embedded tissues from a case-cohort sample of BIG 1–98. EarlyR identifies a set of high-risk patients with relatively poor prognosis who may be considered for additional treatment. Further studies will focus on analyzing the predictive value of EarlyR signature

Pion photoproduction on the nucleon in the quark model

We present a detailed quark-model study of pion photoproduction within the effective Lagrangian approach. Cross sections and single-polarization observables are investigated for the four charge channels, $\gamma p\to \pi^+ n$, $\gamma n\to \pi^- p$, $\gamma p\to \pi^0 p$, and $\gamma n\to \pi^0 n$. Leaving the $\pi N\Delta$ coupling strength to be a free parameter, we obtain a reasonably consistent description of these four channels from threshold to the first resonance region. Within this effective Lagrangian approach, strongly constrainted by the quark model, we consider the issue of double-counting which may occur if additional {\it t}-channel contributions are included.Comment: Revtex, 35 pages, 16 eps figures; version to appear on PR