Elementary immunology: Na(+) as a regulator of immunity

The skin can serve as an interstitial Na(+) reservoir. Local tissue Na(+) accumulation increases with age, inflammation and infection. This increased local Na(+) availability favors pro-inflammatory immune cell function and dampens their anti-inflammatory capacity. In this review, we summarize available data on how NaCl affects various immune cells. We particularly focus on how salt promotes pro-inflammatory macrophage and T cell function and simultaneously curtails their regulatory and anti-inflammatory potential. Overall, these findings demonstrate that local Na(+) availability is a promising novel regulator of immunity. Hence, the modulation of tissue Na(+) levels bears broad therapeutic potential: increasing local Na(+) availability may help in treating infections, while lowering tissue Na(+) levels may be used to treat, for example, autoimmune and cardiovascular diseases

On the renormalization group for the interacting massive scalar field theory in curved space

The effective action for the interacting massive scalar field in curved space-time is derived using the heat-kernel method. Starting from this effective action, we establish a smooth quadratic form of the low-energy decoupling for the four-scalar coupling constant and for the nonminimal interaction parameter. The evolution of this parameter from the conformal value 1/6 at high energies down to the IR regime is investigated within the two toy models with negative and positive four-scalar coupling constants.Comment: LaTeX, 12 pages, 4 figure

Pseudoscalar Meson Mixing in Effective Field Theory

We show that for any effective field theory of colorless meson fields, the mixing schemes of particle states and decay constants are not only related but also determined exclusively by the kinetic and mass Lagrangian densities. In the general case, these are bilinear in terms of the intrinsic fields and involve non-diagonal kinetic and mass matrices. By applying three consecutive steps this Lagrangian can be reduced into the standard quadratic form in terms of the physical fields. These steps are : (i) the diagonalization of the kinetic matrix, (ii) rescaling of the fields, and (iii) the diagonalization of the mass matrix. In case, where the dimensions of the non-diagonal kinetic and mass sub-matrices are respectively, $k\times k$ and $n\times n$, this procedure leads to mixing schemes which involve $[k(k-1)/2] + [n(n-1)/2]$ angles and $k$ field rescaling parameters. This observation holds true irrespective with the type of particle interactions presumed. The commonly used mixing schemes, correspond to a proper choice of the kinetic and mass matrices, and are derived as special cases. In particular, $\eta$-$\eta '$ mixing, requires one angle, if and only if, the kinetic term with the intrinsic fields has a quadratic form.Comment: REVTeX, 6 page

How large could the R-parity violating couplings be?

We investigate in detail the predictions coming from the d=4 operators for proton decay. We find the most general constraints for the R-parity violating couplings coming from proton decay, taking into account all fermion mixing and in different supersymmetric scenarios.Comment: 8 pages, several corrections, to appear in J.Phys.G (2005

Can we distinguish between h^{SM} and h^0 in split supersymmetry?

We investigate the possibility to distinguish between the Standard Model Higgs boson and the lightest Higgs boson in Split Supersymmetry. We point out that the best way to distinguish between these two Higgs bosons is through the decay into two photons. It is shown that there are large differences of several percent between the predictions for \Gamma(h\to\gamma\gamma) in the two models, making possible the discrimination at future photon-photon colliders. Once the charginos are discovered at the next generation of collider experiments, the well defined predictions for the Higgs decay into two photons will become a cross check to identify the light Higgs boson in Split Supersymmetry.Comment: 8 pages, 3 Figures, typos fixed, version published in J.Phys. G31 (2005) 563-56

Renormalization-Scale-Invariant PQCD Predictions for R_e+e- and the Bjorken Sum Rule at Next-to-Leading Order

We discuss application of the physical QCD effective charge $\alpha_V$, defined via the heavy-quark potential, in perturbative calculations at next-to-leading order. When coupled with the Brodsky-Lepage-Mackenzie prescription for fixing the renormalization scales, the resulting series are automatically and naturally scale and scheme independent, and represent unambiguous predictions of perturbative QCD. We consider in detail such commensurate scale relations for the $e^+e^-$ annihilation ratio $R_{e^+e^-}$ and the Bjorken sum rule. In both cases the improved predictions are in excellent agreement with experiment.Comment: 13 Latex pages with 5 figures; to be published in Physical Review

Higgs Boson Mass in Low Scale Gauge Mediation Models

We consider low scale gauge mediation models with a very light gravitino m_{3/2}~16 eV, in the light of recent experimental hints on the Higgs boson mass. The light gravitino is very interesting since there is no gravitino over-production problem, but it seems difficult to explain the Higgs boson mass of ~125 GeV. This is because of the conflict between the light gravitino mass and heavy SUSY particle masses needed for producing the relatively heavy Higgs boson mass. We consider two possible extensions in this paper: a singlet extension of the Higgs sector, and strongly coupled gauge mediation. We show that there is a large parameter space, in both scenarios, where the Higgs boson mass of ~125 GeV is explained without any conflict with such a very light gravitino.Comment: 23 pages, 5 figure

Electroweak pinch technique to all orders

The generalization of the pinch technique to all orders in the electroweak sector of the Standard Model within the class of the renormalizable 't Hooft gauges, is presented. In particular, both the all-order PT gauge-boson-- and scalar--fermions vertices, as well as the diagonal and mixed gauge-boson and scalar self-energies are explicitly constructed. This is achieved through the generalization to the Standard Model of the procedure recently applied to the QCD case, which consist of two steps: (i) the identification of special Green's functions, which serve as a common kernel to all self-energy and vertex diagrams, and (ii) the study of the (on-shell) Slavnov-Taylor identities they satisfy. It is then shown that the ghost, scalar and scalar--gauge-boson Green's functions appearing in these identities capture precisely the result of the pinching action at arbitrary order. It turns out that the aforementioned Green's functions play a crucial role, their net effect being the non-trivial modification of the ghost, scalar and scalar--gauge-boson diagrams of the gauge-boson-- or scalar--fermions vertex we have started from, in such a way as to dynamically generate the characteristic ghost and scalar sector of the background field method. The pinch technique gauge-boson and scalar self-energies are also explicitly constructed by resorting to the method of the background-quantum identities.Comment: 48 pages, 8 figures; v2: typos correcte

Resummation of the hadronic tau decay width with the modified Borel transform method

A modified Borel transform of the Adler function is used to resum the hadronic tau decay width ratio. In contrast to the ordinary Borel transform, the integrand of the Borel integral is renormalization--scale invariant. We use an ansatz which explicitly accounts for the structure of the leading infrared renormalon. Further, we use judiciously chosen conformal transformations for the Borel variable, in order to map sufficiently away from the origin the other ultraviolet and infrared renormalon singularities. In addition, we apply Pade approximants for the corresponding truncated perturbation series of the modified Borel transform, in order to further accelerate the convergence. Comparing the results with the presently available experimental data on the tau hadronic decay width ratio, we obtain $\alpha_s(M^z) = 0.1192 +- 0.0007_{exp.} +- 0.0010_{EW+CKM} +- 0.0009_{th.} +- 0.0003_{evol.}$. These predictions virtually agree with those of our previous resummations where we used ordinary Borel transforms instead.Comment: 32 pages, 2 eps-figures, revtex; minor changes in the formulations; a typo in Eq.(47) corrected; version as appearing in Phys. Rev.