The Spanish Lesbian Collective LSD: A Closer Look to Their Video-Essay Retroalimentación (1998)

In 1993, the group LSD (Lesbianas sin duda / Lesbians without a doubt) was created in Madrid. It was a collective of artivists including Itziar Okariz Virginia Villaplana, Fefa Vila, Azucena Vietes, Marisa Maza, and Liliana Couso, among others.  They met in the downtown neighbourhood of Lavapiés to publish magazines and fanzines such as Bollozine or Non Grata, dedicated to film, music, photography, and the Spanish queer art scene overall. In addition, they carried out two photographic projects that are already part of the national lesbian imaginary: Es-Cultura lesbiana and Monstruosidades. This collective, which uses artistic channels for activism, takes a model of a community that is no longer a conqueror of rights (liberalism) but rather a destroyer of all aspects of a hierarchical society. Queer activism is located at the margins of representation, understood as “an abject margin full of monsters, in which race, class and sex are mixed, ready to come to light and destabilize the dominant discourses" (García, 2016, p. 162). Violence is no longer understood individually but within a social structure. Some of these artists later continued their careers with video actions and performances in public places, exposing their bodies and thus problematising their gender and sexual orientation, as several of them contributed to the visibility of lesbians in Spain at the turn of the century.  This article analyses the photographic and collage work of the Spanish lesbian collective LSD, taking as object of study the video essay Retroalimentación (1998), made by the LSD member Virginia Villaplana

Diseño del Workshop El documental contemporáneo dirigido por mujeres. Construyendo puentes entre Latinoamérica y España, una experiencia pedagógica

This training experience has been designed to address the scarce incursions in the study of contemporary documentary film. We focus on female directed cinema in Spain and in Spanish-speaking Latin American Countries. It is therefore suggested an approach based on the field theories of Francesco Casetti, the feminist film studies and the later specific analysis of documentary film that emerged in the 1990s, especially the scheme developed by Bill Nichols. The methodology employed for the workshop, taught in the context of the Gendercom congress at the University of Seville, was based on the selection of the filmographies of 18 female directors, with a sum of 100 titles in the sample. It has been classified according to 7 thematic axes. In response to the Covid-19 virus situation, its celebration has turned it into an international academic activity.Esta experiencia formativa ha sido diseñada en consideración con las escasas incursiones en el estudio del cine documental contemporáneo dirigido por mujeres en España y en países de Latinoamérica hispanohablantes. Se propone un enfoque desde las teorías de campo de F. Casetti, los estudios fílmicos feministas y los posteriores análisis específicos de cine documental surgidos en la década de 1990, en especial el esquema propuesto por Bill Nichols. La metodología del taller, impartido en el contexto del congreso Gendercom de la Universidad de Sevilla, ha partido de la selección de las filmografías de 18 directoras, con un total de 100 títulos en la muestra que han sido clasificados en torno a 7 ejes temáticos. Ante la situación del virus Covid-19 su celebración online lo ha convertido en una actividad académica internacional

La diversidad en los centros de secundaria desde la perspectiva de orientación

El objetivo de este estudio fue constatar mediante la opinión de los responsables de los Departamentos de Orientación, la incidencia del centro educativo de secundaria en la atención a la diversidad. En el estudio participaron 75 profesionales con edades entre los 25 y 65 años (M= 44.5±10.45). Se administró el cuestionario para la evaluación de la atención a la diversidad (EVADIE). Los resultados obtenidos ponen de manifiesto que los centros educativos deben proporcionar ocasiones a todo el alumnado en el logro de sus objetivos a través de a través la filosofía de la coeducación (inclusión)

Expansion of different subpopulations of CD26−/low T cells in allergic and non-allergic asthmatics

Asthma; Allergy; CD26Asma; Al·lèrgia; CD26Asma; Alergia; CD26CD26 displays variable levels between effector (TH17 ≫ TH1 > TH2 > Treg) and naïve/memory (memory > naïve) CD4+ T lymphocytes. Besides, IL-6/IL-6R is associated with TH17-differentiation and asthma severity. Allergic/atopic asthma (AA) is dominated by TH2 responses, while TH17 immunity might either modulate the TH2-dependent inflammation in AA or be an important mechanism boosting non-allergic asthma (NAA). Therefore, in this work we have compared the expression of CD26 and CD126 (IL-6Rα) in lymphocytes from different groups of donors: allergic (AA) and non-allergic (NAA) asthma, rhinitis, and healthy subjects. For this purpose, flow cytometry, haematological/biochemical, and in vitro proliferation assays were performed. Our results show a strong CD26-CD126 correlation and an over-representation of CD26- subsets with a highly-differentiated effector phenotype in AA (CD4+CD26-/low T cells) and NAA (CD4-CD26- γδ-T cells). In addition, we found that circulating levels of CD26 (sCD26) were reduced in both AA and NAA, while loss of CD126 expression on different leukocytes correlated with higher disease severity. Finally, selective inhibition of CD26-mRNA translation led to enhanced T cell proliferation in vitro. These findings support that CD26 down-modulation could play a role in facilitating the expansion of highly-differentiated effector T cell subsets in asthma

Effects of Gestational Intermittent Hypoxia on Placental Morphology and Fetal Development in a Murine Model of Sleep Apnea

Obstructive sleep apnea (OSA) during pregnancy is characterized by episodes of intermittent hypoxia (IH) during sleep, resulting in adverse health outcomes for mother and offspring. Despite a prevalence of 8-20% in pregnant women, this disorder is often underdiagnosed.We have developed a murine model of gestational OSA to study IH effects on pregnant mothers, placentas, fetuses, and offspring. One group of pregnant rats was exposed to IH during the last 2 weeks of gestation (GIH). One day before the delivery date, a cesarean section was performed. Other group of pregnant rats was allowed to give birth at term to study offspring's evolution.Preliminary results showed no significant weight differences in mothers and fetuses. However, the weight of GIH male offspring was significantly lower than the controls at 14 days (p < 0.01). The morphological study of the placentas showed an increase in fetal capillary branching, expansion of maternal blood spaces, and number of cells of the external trophectoderm in the tissues from GIH-exposed mothers. Additionally, the placentas from the experimental males were enlarged (p < 0.05). Further studies are needed to follow the long-term evolution of these changes to relate the histological findings of the placentas with functional development of the offspring in adulthood.Ayudas para la realización de proyectos de investigación UVa 2021 (PROYEMER 57-E.O.

Expansion of different subpopulations of CD26−/low T cells in allergic and non-allergic asthmatics

CD26 displays variable levels between effector (TH17 ≫ TH1 > TH2 > Treg) and naïve/memory (memory > naïve) CD4+ T lymphocytes. Besides, IL-6/IL−6R is associated with TH17-differentiation and asthma severity. Allergic/atopic asthma (AA) is dominated by TH2 responses, while TH17 immunity might either modulate the TH2-dependent inflammation in AA or be an important mechanism boosting non-allergic asthma (NAA). Therefore, in this work we have compared the expression of CD26 and CD126 (IL-6Rα) in lymphocytes from different groups of donors: allergic (AA) and non-allergic (NAA) asthma, rhinitis, and healthy subjects. For this purpose, flow cytometry, haematological/biochemical, and in vitro proliferation assays were performed. Our results show a strong CD26-CD126 correlation and an over-representation of CD26− subsets with a highly-differentiated effector phenotype in AA (CD4+CD26−/low T cells) and NAA (CD4−CD26− γδ-T cells). In addition, we found that circulating levels of CD26 (sCD26) were reduced in both AA and NAA, while loss of CD126 expression on different leukocytes correlated with higher disease severity. Finally, selective inhibition of CD26-mRNA translation led to enhanced T cell proliferation in vitro. These findings support that CD26 down-modulation could play a role in facilitating the expansion of highly-differentiated effector T cell subsets in asthma.This work was supported by grants from Sociedad Española de Neumología y Cirugía Torácica, (SEPAR) (121/2012) and Instituto de Salud Carlos III, Ministerio de Economía y Competitividad (Fondo de Investigación Sanitaria, FIS; co-financed by European Union ERDF funds) (PI13/02046). JJN-F is a recipient of a Xunta de Galicia Fellowship (co-financed by European Social Fund (ESF))S

Preparation and surface functionalization of MWCNTs: study of the composite materials produced by the interaction with an iron phthalocyanine complex

Carbon nanotubes [CNTs] were synthesized by the catalytic vapor decomposition method. Thereafter, they were functionalized in order to incorporate the oxygen groups (OCNT) and subsequently the amine groups (ACNT). All three CNTs (the as-synthesized and functionalized) underwent reaction with an iron organometallic complex (FePcS), iron(III) phthalocyanine-4,4",4",4""-tetrasulfonic acid, in order to study the nature of the interaction between this complex and the CNTs and the potential formation of nanocomposite materials. Transmission electronic microscopy, N2 adsorption at 77 K, thermogravimetric analysis, temperature-programmed desorption, and X-ray photoelectron spectroscopy were the characterization techniques employed to confirm the successful functionalization of CNTs as well as the type of interaction existing with the FePcS. All results obtained led to the same conclusion: There were no specific chemical interactions between CNTs and the fixed FePcS

Association between vitamin D receptor rs731236 (Taq1) polymorphism and risk for restless legs syndrome in the Spanish caucasian population

Varios trabajos recientes sugieren un posible papel de la deficiencia de vitamina D en la etiología o el síndrome de las piernas inquietas (RLS). Hemos analizado la posible relación de 2 polimorfismos de un solo nucleótido (SNP) en el receptor de la vitamina D3 (GEN VDR) con el riesgo de SPI. Hemos estudiado la variante alélica genotipo y frecuencias de VDR rs2228570 y rs731236 VDR SNPs en 205 RLS pacientes y 445 controles sanos mediante un ensayo TaqMan. Las frecuencias de los rs731236AAgenotype y la variante alélica rs731236un SPI fue significativamente inferior en los pacientes que en los controles (P<0,005 y 0,01, respectivamente). El síndrome de las piernas inquietas pacientes portadoras de la variante alélica rs731236G había una edad temprana en el inicio, y los portadores del genotipo GG731236rs tuvieron mayor severidad de RLS, aunque estos datos desaparecieron después de los análisis multivariados. Ninguno de los SNPs estudiados estaba relacionada con la positividad de la historia familiar de SPI. Estos resultados sugieren una modesta, pero significativa asociación entre rs731236 VDR SNP y el riesgo de síndrome de piernas inquietas.Several recent works suggest a possible role of vitamin D deficiency in the etiology or restless legs syndrome (RLS). We analyzed the possible relationship of 2 common single nucleotide polymorphisms (SNPs) in the vitamin D3 receptor (VDR) gene with the risk for RLS. We studied the genotype and allelic variant frequencies of VDR rs2228570 and VDR rs731236 SNPs in 205 RLS patients and 445 healthy controls using a TaqMan essay. The frequencies of the rs731236AAgenotype and the allelic variant rs731236A were significantly lower in RLS patients than in controls (P<0.005 and<0.01, respectively). Restless legs syndrome patients carrying the allelic variant rs731236G had an earlier age at onset, and those carrying the rs731236GG genotype had higher severity of RLS, although these data disappeared after multivariate analyses. None of the SNPs studied was related with the positivity of family history of RLS. These results suggest a modest, but significant association between VDR rs731236 SNP and the risk for RLS.• Instituto de Salud Carlos III, Madrid, Fondo de Investigación Sanitaria: Ayudas PI12/00241, PI12/00324, y RETICS RD12/0013/0002 • Junta de Extremadura: GR15026 y PRIS10016 • Ministerio de Ciencia e Innovación: Ayudas SAF2006-10126 (2006–2009) y SAF2010-22329-C02-01 (2011-2013) • Parciamente financiado con Fondos FEDERpeerReviewe