Ontological Reengineering for Reuse

This paper presents the concept of Ontological Reengineering as the process of retrieving and transforming a conceptual model of an existing and implemented ontology into a new, more correct and more complete conceptual model which is reimplemented. Three activities have been identified in this process: reverse engineering, restructuring and forward engineering. The aim of Reverse Engineering is to output a possible conceptual model on the basis of the code in which the ontology is implemented. The goal of Restructuring is to reorganize this initial conceptual model into a new conceptual model, which is built bearing in mind the use of the restructured ontology by the ontology/application that reuses it. Finally, the objective of Forward Engineering is output a new implementation of the ontology. The paper also discusses how the ontological reengineering process has been applied to the Standard-Units ontology [18], which is included in a Chemical-Elements [12] ontology. These two ontologies will be included in a Monatomic-Ions and Environmental-Pollutants ontologies

To the vicinity and beyond! Production, distribution and trade of cooking greywares in medieval Catalonia, Spain

Utilitarian greyware ceramics are one of the most abundant artefacts at rural sites in Medieval Catalonia, Spain, and were manufactured by numerous long-lived production centres. The stylistic homogeneity of this class of pottery has traditionally restricted its contribution to the archaeological interpretation of the region. However, recent scientific analyses of excavated kiln sites are offering new perspectives via the establishment of compositional reference groups for greyware ceramics. Using one such dataset, from the large workshop of Cabrera d’Anoia, this paper examines the distribution and consumption of utilitarian grey pottery at 25 Medieval sites across Catalonia. The study reveals a pattern of several regional production centres distributing their goods to small villages within the surrounding countryside and, in some cases, competing for rural markets. This is interpreted in terms of the mechanisms by which greyware pottery was distributed, as well as the socio-political and religious influences on its supply and demand in Medieval Catalonia

Ontology's crossed life cycles

This paper presents the idea that the life cycle of an ontology is highly impacted as a result of the process of reusing it for building another ontology. One of the more important results of the experiment presented is how the different activities to be carried out during the development of a specific ontology may involve performing other types of activities on other ontologies already built or under construction. We identify in that paper new intradependencies between activities carried out inside the same otology and interdependencies between activities carried out in different ontologies. The interrelation between life cycles of several ontologies provokes that integration has to be approached globally rather than as a mere integration of out implementation

Homeless in Dhaka: Violence, Sexual Harassment, and Drug-abuse

Bangladesh has experienced one of the highest urban population growth rates (around 7% per year) over the past three decades. Dhaka, the capital city, attracts approximately 320,000 migrants from rural areas every year. The city is unable to provide shelter, food, education, healthcare, and employment for its rapidly-expanding population. An estimated 3.4 million people live in the overcrowded slums of Dhaka, and many more live in public spaces lacking the most basic shelter. While a small but growing body of research describes the lives of people who live in urban informal settlements or slums, very little research describes the population with no housing at all. Anecdotally, the homeless population in Dhaka is known to face extortion, erratic unemployment, exposure to violence, and sexual harassment and to engage in high-risk behaviours. However, this has not been systematically documented. This cross-sectional, descriptive study was conducted to better understand the challenges in the lives of the homeless population in 11 areas of Dhaka during a 13-month period from June 2007 to June 2008. A modified cluster-sampling method was used for selecting 32 clusters of 14 female and male respondents, for a sample of 896. In addition to sociodemographic details, this paper focuses specifically on violence, drug-abuse, and sexual harassment. The findings showed that physical assaults among the homeless, particularly among women, were a regular phenomenon. Eighty-three percent of female respondents (n=372) were assaulted by their husbands, station masters, and male police officers. They were subjected to lewd gestures, unwelcome advances, and rape. Male respondents reported being physically assaulted while trying to collect food, fighting over space, or while stealing, by police officers, miscreants, or other homeless people. Sixty-nine percent of the male respondents (n=309) used locally-available drugs, such as marijuana and heroin, and two-thirds of injecting drug-users shared needles. The study determined that the homeless are not highly mobile but tend to congregate in clusters night after night. Income-generating activities, targeted education, gender-friendly community police programmes, shelters and crises centres, and greater community involvement are suggested as policy and programmatic interventions to raise the quality of life of this population. In addition, there is a need to reduce high rates of urban migration, a priority for Bangladesh

Clinical and Resource Utilization Patterns in Patients with Refractory Neuropathic Pain Prescribed Pregabalin for the First Time in Routine Medical Practice in Primary Care Settings in Spain

Abstract Context and Objective. To describe clinical and resource utilization patterns in patients with refractory neuropathic pain (NeP) who were prescribed pregabalin for the first time in routine medical practice in primary care settings. Methods. Post-hoc analysis of a 12-week prospective observational study including pregabalin naïve adult patients with refractory chronic NeP of at least 6-months duration. Self-reported pain intensity, disability, sleep disturbances, symptoms of anxiety and depression, disability, health-related quality of life (HRQoL), health care resource utilization, and corresponding costs were assessed in this post-hoc analysis. Results. One thousand three hundred fifty-four patients were enrolled in the study, and three treatment groups were identified: 1) 598 patients replaced prior pain treatments with pregabalin as monotherapy; 2) 589 added pregabalin to their existing pain treatments; and 3) 167 other pain treatments were prescribed according with physician routine medical practice. Statistically significant differences were reported at baseline for intensity of pain, patient disability, severity of depressive symptoms, and HRQoL (P < 0.01 in all cases). No statistically significant differences were reported among the three treatment groups for anxiety bs_bs_banner Pain Medicine 2013; 14: 1954-1963 1954 severity or sleep disturbances. Subjects who received add-on pregabalin had greater use of direct and indirect resources vs the other groups, resulting in significantly higher quarterly overall costs per patient: €2,397 (2,308), €2,470 (1,857), and €3,110 (2,496), respectively (P < 0.001). Conclusion. These findings suggest that primary care physicians chose pregabalin as an option for treating refractory patients who tended to have much more severe NeP profiles, costing society more than when they chose other therapeutic strategies not including pregabalin

Sequential repeated tibial tubercle osteotomy in a two-stage exchange strategy : a superior approach to treating a chronically infected knee arthroplasty?

Surgical approach can impact the reliability of the debridement after a chronic total knee periprosthetic joint infection (PJI), a factor of utmost importance to eradicate the infection. The most adequate knee surgical approach in cases of PJI is a matter of debate. The purpose of this study was to determine the influence of performing a tibial tubercle osteotomy (TTO) in a two-stage exchange protocol for knee PJI treatment. Retrospective cohort study examining patients managed with two-stage arthroplasty due to chronic knee PJI (2010-2019). Performance and timing of the TTO were collected. Primary end-point was infection control with a minimum FU of 12 months and according to internationally accepted criteria. Correlation between TTO timing and reinfection rate was reviewed. Fifty-two cases were finally included. Overall success (average follow-up: 46.2 months) was 90.4%. Treatment success was significantly higher among cases addressed using TTO during the second stage (97.1% vs. 76.5%, pvalue 0.03). Only 4.8% of the patients relapsed after performing a sequential repeated TTO, that is, during both first and second stages, compared to 23.1% cases in which TTO was not done (p value 0.28). No complications were observed among patients in the TTO group with a significant decrease in soft tissue necrosis (p: 0.052). Sequential repeated tibial tubercle osteotomy during a two-stage strategy is a reasonable option and offers high rates of infection control in complex cases of knee PJI with a low rate of complications

Clinical Evaluation of the Nose: A Cheap and Effective Tool for the Nasal Fracture Diagnosis

Abstract Objective: An accurate diagnosis of nasal fracture is dependent on a thorough history and physical examination. The purpose of this investigation was to create a simple method to establish the diagnosis of nasal fracture based only on clinical criteria. Methods: A retrospective chart review was carried out of 220 patients suspected of nasal fracture admitted to a hospital specializing in occupational injuries in 2003 and 2004. Sensitivity, specificity, and positive/negative predictive value (PPV/NPV) were calculated for each clinical criterio

Sun-dried pears: Phenolic compounds and antioxidant activity.

Two different regional varieties of pears, S. Bartolomeu and Amêndoa, were analyzed fresh and after sun-drying. The total phenolic composition and antioxidant capacity of these pears were determined. The total antioxidant capacity was compared using two different methods: DMPD (N,N-dimethyl-p-phenylenediamine) and the method of ABTS (2,2’-azinobis(3-ethylbenzothiazoline-6-sulfonic acid)) radical scavenging. The ABTS method, when compared with the DMPD method, showed a better correlation between the content of phenolic compounds of the pears and their antioxidant activity. The fresh pear possessed higher amounts of phenolic compounds and higher antioxidant capacity when compared to sun-dried pear. The antioxidant efficiency was expressed as Trolox equivalent and as ascorbic acid equivalent. For both methods, the Trolox equivalent was higher than the ascorbic acid equivalent

Smoking and incidence of glaucoma The SUN Cohort

Abstract Smoking is a serious global public health concern that has been related to many chronic diseases. However, the effect of smoking on eye disorders has been less studied. The aim of this cohort study was to assess the association between current tobacco smokers and the risk of developing glaucoma and furthermore to evaluate the relationship between passive or former smokers and glaucoma. In this prospective and dynamic cohort, 16,797 participants initially who were found not to have glaucoma were followed up for a median of 8.5 years. Validated data on lifestyle, including tobacco consumption, were assessed at baseline. Information about new diagnosis of glaucoma was collected by follow-up questionnaires every 2 years. The outcome was the incidence of self-reported glaucoma during the follow-up. A subsample was used to validate the glaucoma diagnosis. During the 8.5 years of follow-up, 184 new glaucoma cases were identified. Current smokers had a significantly higher risk of glaucoma compared to participants who had never smoked after controlling for potential confounders (Hazard ratio [HR] 1.88 [95% coefficient interval (CI): 1.26-2.81]; P = 0.002). A nonsignificant increased risk was found among former smokers (HR 1.27 [95% CI: 0.88-1.82]; P = 0.198). When we assessed the exposure as per the number of cigarette pack-years, a dose-response relationship between pack-years and the risk of glaucoma was found (HR for the 5th quintile versus the 1st quintile: 1.70 [95% IC: 1.10-2.64], P for trend, 0.009). However, no relationship was found between passive smokers and glaucoma. ]; P = 0.189). Our results suggest a direct association between current smokers and the incidence of glaucoma. In particular, this association was related to the number of pack-years, which was not found in the case of former smokers nor in the case of passive smokers. Abbreviations: IOP = intraocular pressure, POAG = primary open angle glaucoma, SUN = Seguimiento Universidad de Navarra

Cross-Modal Plasticity in Cuban Visually-Impaired Child Cochlear Implant Candidates: Topography of Somatosensory Evoked Potentials

ABSTRACT INTRODUCTION Studies of neuroplasticity have shown that the brain's neural networks change in the absence of sensory input such as hearing or vision. However, little is known about what happens when both sensory modalities are lost (deaf-blindness). Hence, this study of cortical reorganization in visually-impaired child cochlear implant (CI) candidates