Plan de expansión comercial de Mountain Fox

El siguiente trabajo tiene por objetivo explicar, fundamentar y proponer una nueva estrategia de marketing digital para el nuevo emprendimiento Mountain Fox. A través de un análisis que incluye desde la historia de la marca, pasando por sus características, público y actual estrategia, se presentará una propuesta de mejora mediante un plan de marketing digital que tiene por objetivo lograr una mejora en el rendimiento actual tanto en el ámbito online como offline. La nueva estrategia digital estará basada en un fuerte posicionamiento en redes sociales, con un gran apoyo en el buscador más utilizado en el mundo, Google, para posicionar a la marca como una de las más importantes en la mente del consumidor. Esta propuesta se fundamenta en un exhaustivo análisis de las condiciones dadas en un mercado definitivamente cambiante y de comportamiento aleatorio. Gracias a las nuevas estrategias de medición online se logra obtener mayor información y sobre todo conocimiento de una mayor calidad, lo que permite no solo a la empresa, sino a todos aquellos que deseen realizar este tipo de proyectos una mejora en la toma de decisiones para poder reducir la incertidumbre a la hora de tomar decisiones presentes a todo nivel organizacional. Espero encuentren en éste trabajo una solución para empresas de bajo presupuesto o start ups que sirva y genere una mejora en su manejo y creación de contenidos.Fil: Pérez Delgado, Juan Cruz. Universidad Nacional de Cuyo. Facultad de Ciencias Económicas

The role of affect in the development of entrepreneurial intentions

Producción CientíficaAdvances on the study of entrepreneurial intention among students from universities motivate to further investigate the factors behind this intention. In this paper, we focus on the effect of affective traits (positive and negative) on the entrepreneurial intention antecedents proposed by Ajzen’s theory of planned behavior drawing on the arguments of affect priming. Using a sample of 597 students from Spain, we use structural equation model to test our hypotheses. Our results show that positive affective traits have a positive impact on the attitude toward entrepreneurship (ATE), perceived behavioral control of entrepreneurship (PBC), and social norms toward entrepreneurship (SN). Negative affective traits negatively influence ATE and SN, but not PBC. In addition, using a K-means clustering analysis and an analysis of variance, our study further explores how different affective personalities relate to a particular level of entrepreneurial intention. Our results contribute to understand of the psychological processes that influence entrepreneurial intention. Overall, our research contributes to the literature on affect and entrepreneurial cognition by evaluating the interaction of affect and the cognitive antecedents of entrepreneurial intention

Abdomen agudo en paciente con COVID-19

Among the extrapulmonary manifestations of COVID-19, gastrointestinal pathology is acquiring greater relevance since cases are being observed whose initial symptoms are related to this location, in the total absence of respiratory symptoms. This article aims to illustrate a representative case whose debut was an acute abdomen in the absence of respiratory symptoms. In addition, a link is established between the torpid evolution of the surgical process and COVID-19, reinforced by pathological findings. Entre las manifestaciones extrapulmonares de la COVID-19, la patología gastrointestinal está adquiriendo mayor relevancia, ya que se están observando casos cuya sintomatología inicial está relacionada con esta localización, en ausencia total de síntomas respiratorios. Este artículo pretende ilustrar un caso representativo, cuyo debut fue un abdomen agudo en ausencia de clínica respiratoria inicial. Además, se establece un nexo entre la evolución tórpida del proceso quirúrgico y la COVID-19, reforzado por los hallazgos anatomopatológicos

Are interactions between need for achievement and social networks the driving force behind entrepreneurial Intention? A trait activation story

Producción CientíficaEntrepreneurial intention plays a key role in entrepreneurship. Over the years, scholars have explained it using personality traits, cognitive models and, to a lesser extent, the role of social environment. Since this role has been underestimated, we build on trait activation theory to explore how social networks are especially relevant and can trigger the activation of individuals’ need for achievement to predict entrepreneurial intention. We test our hypotheses on a sample of 597 university students from Spain using partial least squares (PLS). Our results confirm that social network size positively influences the entrepreneurial information obtained in social networks, which in turn, positively impacts entrepreneurial intention. Additionally, we found that need for achievement is activated in the context of social networks, enhancing the influence of this information on entrepreneurial intention. Through fuzzy-set qualitative comparative analysis (fsQCA), we also identify alternative configurations of the previous variables that lead to greater entrepreneurial intention

Efectividad del clorhidrato de zilpaterol en la finalización de corderos: Patente vs. Genérico

The objective of this study was to compare the effect of the patent vs. generic sources of zilpaterol hydrochloride (ZH) on the productive performance, carcass characteristics, primary cut yields, and meat quality of lambs finished in feedlot. Thirty (30) Dorper×Pelibuey male lambs were distributed into 10 blocks, each with three lambs of similar initial live weight which were randomly assigned to the following treatments: 1) without ZH (control), 2) with patent ZH (PZH), and 3) with generic ZH (GZH). Treatment means were compared through two orthogonal contrasts: control vs. ZH (PZH+GZH) and PZH vs. GZH. ZH did not affect (P≥0.15) the productive performance, carcass weight, backfat thickness, or fat percentages (kidney-pelvic-heart, mesenteric or omental), but increased (P≤0.05) Longissimus dorsi muscle area and yields of carcass, shoulder, leg, and plain loin. As for the meat quality, ZH did not affect (P≥0.24) pH and shear force, but reduced (P<0.05) redness, yellowness, and chroma color values at 24 h post mortem, as well as the redness value (P<0.01) at 14 days of aging. With exception of carcass yield which tended (P=0.07) to increase with PZH, all measured variables were similar (P³0.14) between PZH and GZH. It has been concluded that both types of ZH at a dose of 0.10 mg per kg of live weight promote muscular hypertrophy in finishing lambs; however, this dosage is not sufficient to result in a better productive performance or carcass weight.El objetivo del estudio fue comparar el efecto de la fuente del clorhidrato de zilpaterol (CZ;  patente vs genérico) sobre el comportamiento productivo, características de la canal, rendimientos de cortes primarios y calidad de la carne de corderos finalizados en corral. Se distribuyeron 30 corderos Dorper ×Pelibuey en 10 bloques donde cada bloque tenía tres corderos de similar peso vivo inicial, los cuales se asignaron aleatoriamente a los siguientes tratamientos: 1) sin CZ (testigo), 2) con CZ de patente (CZP), y 3) con CZ genérico (CZG). Las medias de tratamientos se compararon a través de dos contrastes ortogonales: testigo vs. CZ (CZP+CZG) y CZP vs. CZG. El CZ no afectó (P≥0.15) el comportamiento productivo, peso de la canal, espesor de grasa dorsal, ni los porcentajes de grasa (riñón-corazón-pelvis, mesentérica u omental), pero aumentó (P≤0.05) el área del músculo Longissimus dorsi y los rendimientos de canal, paleta, pierna y lomo plano. En calidad de la carne, el CZ no afectó (P≥0.24) el pH y esfuerzo al corte, pero redujo (P<0.05) los valores de color rojizo, amarillento y chroma a las 24 h post mortem, y también los valores de rojizo (P<0.01) a los 14 días de maduración. Con excepción del rendimiento en canal que tendió (P=0.07) a ser mayor con CZP, todas las variables medidas fueron similares (P³0.14) entre CZP y CZG. Se concluye que ambos tipos de CZ a una dosis de 0.10 mg/kg de peso vivo promueven hipertrofia muscular en corderos de finalización, pero no es suficiente para reflejarse en mejor comportamiento productivo y peso de la canal

Efecto de la adición de clorhidrato de zilpaterol genérico en el perfil bioquímico y hematológico de ovinos de pelo engordados en corral

This study aimed to evaluate zilpaterol hydrochloride (ZH, generic) supplementation on fattening hair sheep, using hematological and biochemical variables as health status indicators. A total of 32 hair lambs (Dorper x Pelibuey) were grouped by initial weight and randomly assigned into four treatments: T1= basal diet (control group), T2= basal diet supplemented with ZH at 0.10 mg·kg-1 of LW d-1 (Grofactor®, Virbac México, Guadalajara, Mexico), T3= basal diet supplemented with ZH at 0.20 mg·kg-1 of LW d-1, and T4= basal diet supplemented with ZH at 0.30 mg·kg-1 of LW d-1. Blood samples were collected on days 1, 15, and 30 of the study. The hematological profile was determined in fresh blood samples; metabolites, electrolytes, and hormones were determined in serum samples. The study followed a randomized complete block experimental design, using an orthogonal polynomial analysis to determine the trend of the responses at the different concentrations of ZH. Cholesterol and urea levels were higher (P<0.05) in T3 than in T2. Furthermore, the mean corpuscular hemoglobin concentration was higher (P<0.05) in T1 than in T3; the red blood cell distribution width was higher (P<0.05) in T2 and T3 than in T4. The Na levels and the number of platelets showed a linear trend (P <0.05) to decrease and increase, respectively, as ZH levels increased. A quadratic trend was observed (P<0.05) in mean corpuscular hemoglobin concentration and red blood cell distribution width with increasing dose of ZH (generic). The remaining variables did not show significant trends at ZH levels (generic). The values of the biochemical and hematological profiles were within the reference range, which suggests that the addition of ZH did not alter the health status of fattening lambs. El objetivo fue evaluar la adición de clorhidrato de zilpaterol (CZ, genérico) en la dieta de ovinos de pelo de engorda, sobre variables hematológicas y bioquímicas como indicadores del estado de salud. Treinta y dos (32) corderos de pelo cruzados (Dorper x Pelibuey) se bloquearon por peso inicial y cuatro tratamientos y se asignaron aleatoriamente dentro de cada bloque: T1= dieta basal (grupo testigo), T2= dieta basal más 0.10 mg·kg-1 de PV d-1 de CZ (Grofactor®, Virbac México, Guadalajara, México), T3= dieta basal más 0.20 mg·kg-1 de PV d-1 de CZ y T4= dieta basal más 0.30 mg·kg-1 de PV d-1 de CZ. Se tomaron muestras de sangre los días 1, 15 y 30 del estudio. El perfil hematológico se estimó en muestras de sangre fresca, mientras que metabolitos, electrolitos y hormonas en muestras de suero. El diseño experimental fue bloques completos al azar y se efectuó análisis de polinomios ortogonales para determinar la tendencia de las respuestas a los niveles de CZ. Los niveles de colesterol y urea fueron mayores (P<0.05) en T3 que en T2; asimismo, el nivel de concentración corpuscular medio de hemoglobina fue mayor (P<0.05) en T1 que en T3, mientras que el ancho de distribución de eritrocitos fue mayor (P<0.05) en T2 y T3 que en T4. Los niveles de Na y el número de plaquetas mostraron tendencia lineal (P<0.05) a disminuir y aumentar, respectivamente, conforme los niveles de CZ aumentaron. Se observó tendencia cuadrática (P<0.05) en la concentración corpuscular media de hemoglobina y ancho de distribución de eritrocitos al aumentar la dosis de CZ (genérico). Las variables restantes no mostraron tendencias significativas a los niveles de CZ (genérico). Los valores de los perfiles bioquímico y hematológico se encontraron dentro del rango de referencia, lo que sugiere que la adición de CZ no alteró el estado de salud de corderos en engorda

Online and Face-to-Face Social Networks and Dispositional Affectivity. How to Promote Entrepreneurial Intention in Higher Education Environments to Achieve Disruptive Innovations?

Producción CientíficaAlthough entrepreneurial intention has been widely studied using cognitive models, we still lack entrepreneurial vocation and, therefore, lack disruptive innovations. Entrepreneurship scholars have some understanding of the reasons underlying this weakness, although there is much room for improvement in our learning concerning how to promote entrepreneurship among university students, especially in the transformed context of digital technologies. This paper focuses on the early stages of start-up, and in particular seeks to evaluate what role social and psychological factors play in the development of entrepreneurial intentions. Drawing on network theory, we consider the impact of social networks on entrepreneurial intention. Specifically, we analyze the influence of two types of social networks: face-to-face and online social networks, with the latter proving especially important in digital transformations. In addition, based on affective congruency theory, we relate affect with entrepreneurial intention. Particularly, we evaluate the influence of positive and negative dispositional affectivity on the formation of entrepreneurial intentions. Finally, since affect and emotions can also be related with social relationships, we analyze whether dispositional affectivities influence entrepreneurial intention through the mediation effect of social networks. Using structural equation modeling, we confirm the impact of both online and face-to-face social networks, as well as positive dispositional affectivity on entrepreneurial intention for 589 higher education students in Spain. However, negative dispositional affectivity is not seen to influence entrepreneurial intention. Furthermore, both face-to-face and online social networks are influenced by positive dispositional affectivity. Moreover, these two types of networks can even partially mediate the relationship between positive dispositional affectivity and entrepreneurial intention. Positive dispositional affectivity can thus influence entrepreneurial intention in two different ways: directly and indirectly through both face-to-face and online social networks. This study provides further insights and adds to the literature on affect, social networks, and entrepreneurial intention. From a broader perspective, we also contribute to the literature on disruptive innovations by explaining how the development of entrepreneurial intentions would have positive consequences for university students vis-à-vis achieving these disruptive innovations.Ministerio de Economía y Competitividad, Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia 2016-2020, project reference ECO2016-78128-P

Trombosis venosa profunda y embolia de pulmón en paciente con hemoperitoneo

The mainstay of the treatment of venous thromboembolism is anticoagulation. Vena cava filters should be considered when there is a contraindication for anticoagulant treatment, a complication of anticoagulation resulting in cessation of therapy or pulmonary embolism recurrence during therapeutic anticoagulation. We present the management of a case of thromboembolic disease in a cancer patient who developed a hemoperitoneum.La anticoagulación es el pilar fundamental del tratamiento de la enfermedad tromboembólica venosa. En las situaciones en las que el tratamiento anticoagulante está contraindicado, como ocurre en una hemorragia activa, o cuando fracasa dicha terapia con recurrencias de la embolia de pulmón, se debe plantear la colocación de un filtro de vena cava inferior. Presentamos el manejo de un caso de enfermedad tromboembólica en un paciente oncológico que desarrolló un hemoperitoneo

Between-session reliability of performance and asymmetry variables obtained during unilateral and bilateral countermovement jumps in basketball players

This study was funded by the Spanish Ministry of Science and Innovation (PID2019- 110074GB-I00 / SRA (State Research Agency) /10.13039/501100011033).This study aimed to evaluate the between-session reliability of single-leg performance and asymmetry variables during unilateral and bilateral countermovement jumps (CMJ). Twenty-three basketball players completed two identical sessions which consisted of four unilateral CMJs (two with each leg) and two bilateral CMJs. Mean and peak values of force, velocity and power, impulse, and jump height were obtained separately for each leg using a dual force platform. All performance variables presented an acceptable reliability (CVrange = 4.05-9.98%) with the exceptions of jump height for the unilateral CMJs and mean power, peak velocity, peak power, and impulse for the left leg during the bilateral CMJ (CV >= 11.0%). Nine out of 14 variables were obtained with higher reliability during the unilateral CMJ (CVratio >= 1.16), and 4 out of 14 during the bilateral CMJ (CVratio >= 1.32). Asymmetry variables always showed an unacceptable reliability (ICCrange = 0.15-0.64) and poor/slight levels of agreement in direction (Kappa(range) = -0.10 to 0.15) for the unilateral CMJ, while an acceptable reliability (ICCrange = 0.74-0.77) and substantial levels of agreement in direction (Kappa(range) = 0.65 to 0.74) were generally obtained for the bilateral CMJ. These results suggest that single-leg performance can be obtained with higher reliability during the unilateral CMJ, while the bilateral CMJ provides more consistent measures of inter-limb asymmetries.Spanish Government PID2019110074GB-I00/SR

R353Q polymorphism in the factor VII gene and cardiovascular risk in Heterozygous Familial Hypercholesterolemia: a case-control study

<p>Abstract</p> <p>Background</p> <p>Heterozygous Familial Hypercholesterolemia (FH) is a genetic disorder characterized by a high risk of cardiovascular disease. Certain polymorphisms of the factor VII gene have been associated with the development of coronary artery disease and there is a known association between factor VII levels and polymorphic variants in this gene. To date, no study has evaluated the association between factor VII and coronary artery disease in patients with FH.</p> <p>Results</p> <p>This case-control study comprised 720 patients (546 with FH and 174 controls). We determined the prevalence and allele frequencies of the R353Q polymorphism of factor VII, the plasma levels of factor VII antigen (FVII Ag) and whether they could be predictive factors for cardiovascular risk. 75% (410) of the patients with FH were RR, 23% (127) RQ and 1.6% (9) QQ; in the control group 75.3% (131) were RR, 21.3% (37) RQ and 3.4% (6) QQ (p = 0.32). No statistically significant associations were observed in the distribution of genotypes and allele frequencies between case (FH) and control groups. Nor did we find differences when we evaluated the relationship between the R353Q polymorphism and cardiovascular risk (including coronary disease, ischemic stroke and peripheral arterial disease), either in the univariate analysis or after adjustment for sex, age, arterial hypertension, body mass index, xanthomas, diabetes, smoking, HDLc and LDLc and lipid-lowering treatment. The FVII Ag concentrations behaved in a similar fashion, with no differences for the interaction between controls and those with FH (RR vs. RQ/QQ; p = 0.96). In the subgroup of patients with FH no association was found among cardiovascular disease, genotype and FVII Ag levels (RR vs. RQ/QQ; p = 0.97).</p> <p>Conclusions</p> <p>Our study did not find a direct relationship between cardiovascular risk in patients with Heterozygous Familial Hypercholesterolemia, the R353Q polymorphism of factor VII and FVII Ag levels.</p