48 research outputs found

    La Asistencia Personal. Un nuevo servicio para las personas mayores desde el Trabajo Social

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    Cada vez la población está más envejecida en nuestro país. Esto es consecuencia del incremento de la esperanza de vida, por lo que cada vez hay más personas mayores con problemas de tipo físico, que son dependientes de sus familiares o tienen que estar en una institución para poder ser atendidas. Esta situación puede provocar en ellas sentimientos de soledad, tanto familiar como social, por la concepción que tiene la sociedad de lo que significa tener a cargo a una persona dependiente de tercera edad. Por todo lo descrito anteriormente, en este trabajo se pretende implantar el servicio de Asistencia Personal como alternativa de atención al colectivo objeto del trabajo. Esta nueva forma de atención generaría en la población destinataria, muchos beneficios que no aportan las formas de atención que se han ido poniendo en marcha hasta ahora, y para los/las asistentes personales que prestarían ayuda y dedicarían parte de su tiempo a estar con estas personas dependientes, supondría mucha satisfacción, ya que verían como éstas cambian su forma de ver la vida, estarían más activas, mejorarían su calidad de vida y la de su entorno más próximo, ya que todos tendrían más libertad para cumplir sus proyectos de vida.Grado en Trabajo Socia

    Postobstructive pulmonary edema (POPE) after laparoscopic appendecectomy: a case report

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    Presentamos el caso de un hombre joven y deportista ingresado por apendicitis aguda. A las pocas horas tras apendicectomía laparoscópica, el paciente comienza con disnea súbita en contexto de edema pulmonar postobstructivo, siendo preciso el ingreso urgente en la unidad de críticos. Debido a la presentación aguda, inesperada y potencialmente fatal de esta patología, realizamos una revisión de la misma.A case report of a young, athletic man admitted for acute appendicitis is presented. A few hours after laparoscopic appendectomy, the patient presented sudden dyspnea in the context of post-obstructive pulmonary edema, requiring urgent admission to the critical care unit. Due to the acute, unexpected and potentially fatal presentation of this pathology, we performed a review focused on it

    Elaboración de vídeos explicativos de las prácticas curriculares del alumnado del Máster de Estudios de Género

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    El proyecto está basado en la elaboración de vídeos explicativos por parte de los responsables de los centros de prácticas con los que tenemos convenios con objeto de explicar el funcionamiento del centro, el objetivo de las prácticas a desarrollar y las funciones del alumnado

    COVID-19 vaccine failure

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    COVID-19 affects the population unequally with a higher impact on aged and immunosuppressed people. Hence, we assessed the effect of SARS-CoV-2 vaccination in immune compromised patients (older adults and oncohematologic patients), compared with healthy counterparts. While the acquired humoral and cellular memory did not predict subsequent infection 18 months after full immunization, spectral and computational cytometry revealed several subsets within the CD8+ T-cells, B-cells, NK cells, monocytes and CD45RA+ CCR7- Tγδ cells differentially expressed in further infected and non-infected individuals not just following immunization, but also prior to that. Of note, up to 7 subsets were found within the CD45RA+ CCR7- Tγδ population with some of them being expanded and other decreased in subsequently infected individuals. Moreover, some of these subsets also predicted COVID-induced hospitalization in oncohematologic patients. Therefore, we hereby have identified several cellular subsets that, even before vaccination, strongly related to COVID-19 vulnerability as opposed to the acquisition of cellular and/or humoral memory following vaccination with SARS-CoV2 mRNA vaccines.This study has been funded through Programa Estratégico Instituto de Biología y Genética Molecular (IBGM Junta de Castilla y León. Ref. CCVC8485), Junta de Castilla y León (Proyectos COVID 07.04.467B04.74011.0) and the European Commission – NextGenerationEU (Regulation EU 2020/2094), through CSIC's Global Health Platform (PTI Salud Global; SGL21-03-026 and SGL2021-03-038)N

    Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

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    The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

    PhDAY 2020 -FOO (Facultad de Óptica y Optometría)

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    Por cuarto año consecutivo los doctorandos de la Facultad de Óptica y Optometría de la Universidad Complutense de Madrid cuentan con un congreso propio organizado por y para ellos, el 4º PhDAY- FOO. Se trata de un congreso gratuito abierto en la que estos jóvenes científicos podrán presentar sus investigaciones al resto de sus compañeros predoctorales y a toda la comunidad universitaria que quiera disfrutar de este evento. Apunta en tu agenda: el 15 de octubre de 2020. En esta ocasión será un Congreso On-line para evitar que la incertidumbre asociada a la pandemia Covid-19 pudiera condicionar su celebración

    Antioxidant capacity of walnut (Juglans regia L.): Contribution of oil and defatted matter

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    Several studies have concluded that walnut exhibits greater antioxidant capacity than any other nuts. However, the contribution to antioxidant capacity of the two major fractions of walnut (defatted matter and oil) is unknown, and the aim of the present work is to elucidate it. Antioxidant capacity was evaluated in walnut oil, defatted matter, and whole walnut. The results showed that the defatted matter provided the bulk of the antioxidant capacity (estimated about 332 μmol Trolox/g dm) of this nut, a major proportion derived from insoluble tannins. The contribution of walnut oil to the overall antioxidant capacity of walnut (FRAP and ABTS assays) is less than a 5%. It was observed that oil interfered in the determination of antioxidant capacity of whole walnut, a fact that could affect the data reported in the literature. Separate determination of oil and defatted mater antioxidant capacity is recommended. © 2007 Springer-Verlag.Peer Reviewe

    Proanthocyanidin content in foods is largely underestimated in the literature data: An approach to quantification of the missing proanthocyanidins

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    8 páginas, 2 figuras, 7 tablas.The content of proanthocyanidins (PA) in foods is usually determined by HPLC analysis of aqueous-organic extracts. However, the appreciable amounts of PA that remain in the residues of extraction usually are not considered for analysis. Attempts to determine these non-extractable proanthocyanidins (NEPA) by enzymatic-chemical methods have obtained partial results. The general aim of this work was the estimation of the total content of PA, including both extractable PA (EPA) and NEPA in some foods included in the USDA database. A specific procedure based on depolymerization by HCl/BuOH treatment was used to quantify NEPA. The content of NEPA in analyzed samples ranged from 11 mg/100 g for pear to 6.7 g/100 g dry weight for red grape pomace. The results showed that literature data underestimate the actual content of PA in foods. NEPA may have a significant contribution to the healthy effects associated to PA-rich foods and diets. © 2009 Elsevier Ltd. All rights reserved.This work is supported by the Spanish Ministry of Innovation and Science (project AGL2008-02541-ALI).Peer reviewe

    "White bile" as a result of a malignant bile obstruction.

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    An 87-year-old female was admitted for endoscopic retrograde cholangiopancreatography (ERCP) due to obstructive jaundice. On admission, total bilirubin was 15 mg/dl at the expense of direct bilirubin, GOT 356 U/l mg/dl, GPT 174 U/l, FA 2,358 U/l and GGT 1,089 U/l. The ERCP showed a prominent, irregular, non-cannulable papilla, so a fistulotomy was performed, emitting a clear, non-mucous fluid. Biliary localization was verified after inserting the guidewire. Cholangiography showed dilatation of the intra-extra hepatic bile duct (common bile duct 18-20 mm). An uncoated metal prosthesis was implanted and a biopsy was performed, confirming papillary adenocarcinoma
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