Prirodna i antropogena distribucija teškog metala(cu) u sedimenetima Trabzonskog region Crnog Mora

In this study, dispersion of Cu element was examined in the coastline of Trabzon, which is the most populated and industrialized part of the Eastern Black Sea region. Sampling studies were carried out in 3 distinct areas on the coast of Trabzon, Değirmendere region,Yanbolu region and Solaklı region. In each region, 8 stations were determined to be studied having various distances, from 0 to 250 meters, from the coast within the boundiries of the studied areas. During the study, the bottom sediment layer (0-5 cm) was taken from 3 different regions and a total 24 stations for sediment analysis were established. We found that heavy metal concentration in the Yanbolu region had a minimum concentration value (52,06 ± 14,42 ppm), Solaklı region had a maximum concentration value (78,57 ± 15,84 ppm) and Değirmendere region had a concentration value (63,97 ± 6,92 ppm) in the spring season. Yanbolu region had a minimum concentration value (53,97 ± 9,40 ppm), Solaklı region had a maximum concentration value (90,45 ± 38,46 ppm) and Değirmendere region had a concentration value (61,26 ± 12,78 ppm) in the summer season. Yanbolu region had a minimum concentration value (64,55 ± 7,17 ppm), Solaklı region had a maximum concentration value (107,06 ± 26,98 ppm) and Değirmendere region had a concentration value (86,05 ± 3,19 ppm) in the autumn season. Yanbolu region had a minimum concentration value (56,87 ± 7,71 ppm), Solaklı region had a maximum concentration value (76,21 ± 15,65 ppm) and Değirmendere region had a concentration value (68,70 ± 8,89 ppm) in the winter season. We found that heavy metal (Cu) concentration in the Yanbolu region had the lowest concentration value and Solaklı region had the highest concentration value in the study area in all seasons. According to all seasons, the spring season had the lowest concentration value and the autumn season had the highest concentration value. When the sediment enrichment factor (SEF) is present in all regions, because the SEF values was higher than 1 for the spring reason (Değirmendere region: 1,64, Yanbolu region: 1,39, Solaklı region: 1,79), the summer reason (Değirmendere region: 1,68, Yanbolu region: 1,51, Solaklı region: 2,14), the autumn season (Değirmendere region: 2,02, Yanbolu region: 1,66, Solaklı region: 2,72), the winter (Değirmendere region: 1,87, Yanbolu region: 1,60, Solaklı region: 1,91) of this element, it can be concluded that the sediment layer in Trabzon is rich in this metal. According to Pollution Load Index (PLI), the spring reason (Değirmendere region: 1,15, Yanbolu region: 1,71, Solaklı region: 1,09), the summer reason (Değirmendere region: 1,33, Yanbolu region: 1,18, Solaklı region: 2,87), the autumn season (Değirmendere region: 1,90 Yanbolu region: 1,42, Solaklı region: 2,49), the winter (Değirmendere region: 1,51, Yanbolu region: 1,24, Solaklı region: 1,66) ) of this element have also been calculated. The examination of sediment enrichment factor (SEF) and Pollution Load Index (PLI) reveal the presence of Cu metal which is indicative of heavy metal pollution in the sampling area

Course Assignment Open Science

This is a class assignment for course number PSQ1096300 at University of Padua

Astma and COVID-19

Humanity encountered a coronavirus (severe acute respiratory syndrome-coronavirus-2 (sars-cov-2)) pandemic on december 31, 2019 that is threatening the human race. The disease was first identified in the city of wuhan in china. It causes widespread pneumonia in the lungs, with the most significant laboratory findings being lymphopenia and eosinopenia in the blood count and elevated c-reactive protein and d-dimer. The findings increase with the progression of the clinical picture. Comorbidities in an individual determine the course of the disease, with the most important risk factors among those indicating a severe course being hypertension, ischemic heart disease, diabetes and chronic obstructive pulmonary disease. Asthma represents no increased risk in terms of catching the coronavirus disease-2019 (covid-19), and no report has been published to date associating its risk with a more severe disease course. Covid-19, as with all other respiratory infections, interferes with control of asthma. It is important to keep asthma under control during this period, as always. Patients should not stop taking their inhaled steroids, nor should they reduce the dose. Similarly, systemic steroids should not be stopped if prescribed to keep asthma under control. The use of anti-ige, anti il-5/il-5 alpha and anti il-4 alpha does not increase the risk of contracting covid-19, and these drugs may also be used to maintain asthma under control. A "to do" list should be provided to patients by their physicians as an action plan in the event of a worsening of asthma symptoms. Patients with allergic rhinitis can safely use their nasal steroid and antihistaminic drugs. Hand disinfectants that contain chlorhexidine may cause asthma attacks, and are not active against sars-cov-2. Using latex gloves to ensure hand hygiene may also lead to asthma attacks in individuals with a latex allergy. Washing the hands with water and soap should be preferred rather than using gloves. In conclusion, covid-19 does not constitute a greater risk to patients with asthma. Inhaled steroids and systemic steroids that keep the asthma under control can be used safely. Lowering a step in the treatment of asthma is not recommended in this period

Ecological pathways of heavy metal pollution in Solakli River Basin (River Bed, Uzungol Lake and Estuary) sediment of southeastern Black Sea region, Turkey

62-69In this study, the natural and anthropogenic heavy metal (Cr, Pb, Cu, Zn, Ni and As) pollution in Solakli river basin (river bed, Uzungol lake and estuary) investigated spatially and temporally. The highest metal concentrations were measured in the section influenced by estuary of Solakli. Highest metal concentrations were observed in winter. Metal concentrations were determined using an inductively coupled plasma-mass spectrometer (ICP-MS). Based upon the result of this study and according to Sediment Enrichment Factor (SEF), Pollution Load Index (PLI) and Geoaccumulation Index (IGEO) and SQG (Sediment Quality Guideline), Cu and As are the major contributor to toxicity in the Solakli river basin

DEVELOPMENT AND EVALUTION OF A TURKISH "RHINITIS QUALITY OF LIFE SCALE"

WOS: 000307988400007Objective: Questioning the quality of life in patients with chronic diseases is important. However questionnaires should be suitable to the structure and habits of the community studied as well as it should be easily understood. Considering the fact that rhinitis adversely affect the quality of life, we developed a rhinitis scale of quality of life, which suits the life style and habits of our population in patients with rhinitis. Material and Method: Scale includes the 28 parameters that are needed to be graded and scored about daily activities, nasal symptoms, and eye complaints, sleep disorders in addition to social and emotional assessment. A total of 163 patients with allergic rhinitis, that applied to Allergy division of Internal Medicine Department of Istanbul Medical School have been included into the study Symptoms scoring has been performed with short form 36 (SF-36) and novel scale at week 0, week 1 and 1 month after treatment. The results of newly developed rhinitis quality of life scale were compared with statistical methods for language validity, reliability, repeatability, reproducibility and sensitivity. Results: Language validity of scale was shown (n=20). Intraclass correlation coefficient (ICC) is 0.8877, Cronbach cilia is 0.94; these values are high and represent the reliability of new scale (control at 1. week without treatment n=38). Although there is a weak correlation between the results of new scale and SF-36 sub parameter scores, these correlations were significant in statistical analysis (n=.103) (validation). New scale was significantly sensitive for determining the pre and post treatment changes (n=103) (z=-7.452, p=0.000). Conclusion: This newly developed scale is practical, easy to be administrated in short periods; also it has sufficient reliability, reproducibility, validity and sensitivity characteristics. We concluded that this scale is suitable for both determining the clinical status and response to treatment in patients with allergic rhinitis

Modification of polyacrylonitrile fabric for antibacterial application by tetracycline immobilization

WOS: 000499943400027In recent years, usage of textile materials that made from synthetic polymers increased rapidly due to these products show good durability, resistant to chemicals, abrasion, tension, shrinkage corrugation. Properties of textile products that made from synthetic polymer could be improved and new features could be added via enzymatic modification. in addition, functional medical textile materials could be improved from modified products using the different bioactive compounds. in this study, enzymatic modification of the polyacrylonitrile (PAN) fabric that use in the textile industry were performed and a new product that has antibacterial properties via tetracycline immobilization was developed. For this purpose, first, enzymatic modification of PAN fabric was performed. Nitrilase was used for modification of PAN fabrics. After drying of PAN fabrics that incubated with nitrilase was taken contact angle measurements, SEM images and ATR-FTIR spectra and examined the modification. Carboxylic acid groups consisted in PAN fabric structure as a result of enzymatic modification and tetracycline was immobilized to carboxylic acid groups using 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) at optimum reaction conditions. After immobilization, contact angle measurements, SEM images and ATR-FTIR spectra of PAN fabrics were performed. in addition, antibacterial properties of the obtained product were examined.Ege University Research FoundationEge University [2012-FEN-031]This work was supported by Ege University Research Foundation 2012-FEN-031