79 research outputs found
Anticardiolipin Antibodies In Behcets-Disease
6th International Conference on Bechcets Disease -- JUN 30-JUL 01, 1993 -- PARIS, FRANCEWOS: A1993BZ91R0002
Multicentric reticulohistiocytosis
WOS: A1996TV05200013PubMed ID: 8929779We describe a 42-year-old man with a five-year history of arthritis mutilans-like destructive joint changes and with a one-year history of nodules on the fingers, ears, oral mucosa, pharynx, larynx, vocal cords, some being ulcerated and haemorrhagic. He was diagnosed as having rheumatoid arthritis; however, biopsies from the nodules an the oral mucosa and ear revealed multicentric reticulohistiocytosis, The large nodule over the olecranon process, simulating a rheumatoid nodule but diagnosed as multicentric reticulohistiocytosis with biopsy; ulcerated and haemorrhagic nodules on the oral mucosa; and rapidly progressive joint destructions make our case interesting
A METHOTREXATE RELATED CASE WITH LYMPHADENOPATHIES
5th International Eurasian Hematology Congress -- OCT 15-19, 2014 -- Antalya, TURKEYWOS: 00034724420011
Determination of lupus anticoagulant (LA) and antiphospholipid antibodies (APA) in a family with systemic lupus erythematodes (SLE)
PubMed ID: 1414067The Lupus Anticoagulant (LA) is an immunglobulin directed towards the phospholipid portion of the prothrombin activator complex. This immunglobulin because first identified in the plasma of patients with Systemic Lupus Erythematodes, was named as Lupus Anticoagulant. Although initially described in patients with SLE, it was subsequently observed in other diseases and also in patients without any manifest disease. SLE or similar diseases are present in 35% of LA (+) patients. The LA prevalence in SLE patients has been found as 34% whereas ACA prevalence was found as 44%. While searching for the presence of LA and the levels of APA in cases having unexplained recurrent fetal losses, a family (a mother and 3 daughters) was discovered, whose each member has been diagnosed as SLE at different times and with different symptoms. Data suggesting the presence of LA and high APA levels were determined in all the members of the family and also it was realised that case who had recurrent fetal losses had the highest APA levels. In addition to immunoassay methods to detect APA, examination of coagulation tests in patients with unexplained thrombosis and/or fetal losses, would be of great help
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