Photodynamic Therapy and Extracorporeal Photochemotherapy in Dermatology

Extracorporeal photochemotherapy or photopheresis is an extracorporeal ultraviolet and a photosensitizer (8-MOP) exposure of plasma. It is reported to be effective for several dermatoses such as cutaneous T cell lymphoma, autoimmune diseases and graft versus host disease. Photodynamic therapy involves the use of a photosensitizer in combination with visible light which is the correct wavelight for the photosensitizer. It has become an alternative treatment method for dermatooncologic conditions like actinic keratosis and basal cell carcinoma. In addition to these dermatoses, it is used for many non-neoplastic dermatoses such as acne, localized scleroderma and in some aesthetic indications

The effect of academic risk taking levels on the problem solving ability of gifted students

World Conference on Educational Sciences -- FEB 04-07, 2009 -- Nicosia, CYPRUSWOS: 000275580400190The ability of Academic risk taking is a critical component which considers academic success at the top level. To increase the academic success to a higher level needs adaptation to the present conditions. Adaptation will be possible via problem solving. In this study it has been described that the relationship between the levels of taking academic risk of gifted student with their levels of problem solving abilities. The study data is collected by using data collection tools which are the scale of academic risk taking one of which was developed by Clifford (1991) and was adapted to Turkish by Korkmaz (2002) and another scale of problem solving skills which was developed by Yaman (2003). The opinions of totally 103 students who answered the questions were taken. According to the results; the conclusion was "academic risk taking levels and problem solving ability level of gifted students is positively high. There is a significant relationship between them". (C) 2009 Elsevier Ltd. All rights reserve

Effect of washing with tap water on the quality of sea bass

In this study, a the effects of washing with tap water whole and gutted sea bass (Dicentrarchus labrax) were evaluated. Fish evaluation for 13 days of storage in ice included sensory analyses, chemical and microbiological changes. Total volatile basic nitrogen (TVB-N) and Trimethylamin (TMA-N) values showed significant increase for all group sea bass samples during storage (p=0.05). Sensory evaluation showed a reasonably good correlation with bacterial populations. It has been determined that washing procedure is reducing the microbiological load. Results of this study indicated that the acceptability quality of washed and not washed sea bass as determined by sensorial, chemical and microbiological data is 11 days, respectively

Investigation of ischemia modified albumin and coenzyme Q10 levels in obese children with metabolic syndrome

Introduction: The aim of this study was to analyze serum ischemia modified albumin (IMA) and plasma CoQ10 levels and to evaluate their correlation with insulin resistance (homeostatic model assessment, HOMA) and lipid profile in obese children with and without metabolic syndrome (MS)

Cyclin D1 Gene G870A Variants and Primary Brain Tumors

Alterations of cyclin D1, one of the main regulators of the cell cycle, are known to be involved in various cancers. The CCDN1 G870A polymorphism causes production of a truncated variant with a shorter half-life and thus thought to impact the regulatory effect of CCDN1. The aim of the present study was to contribute to existing results to help to determine the prognostic value of this specific gene variant and evaluate the role of CCDN1 G870A polymorphism in brain cancer susceptibility. A Turkish study group including 99 patients with primary brain tumors and 155 healthy controls were examined. Genotypes were determined by polymerase chain reaction-restriction fragment length polymorphism analysis. The CCDN1 genotype frequencies in meningioma, glioma and control cases were not significantly different (p>0.05). No significant association was detected according to clinical parameters or tumor characteristics; however, a higher frequency of AG genotype was recorded within patients with astrocytic or oligoastrocytic tumors. A significant association between AG genotype and gliobilastoma multiforme (GBM) was recorded within the patients with glial tumors (p value=0.048 OR: 1.87 CI% 1.010-3.463). According to tumor characteristics, no statistically significant difference was detected within astrocytic, oligoasltrocytic tumors and oligodentrioglias. However, patients with astrocytic astrocytic or oligoastrocytic tumors showed a higher frequency of AG genotype (50%) when compared to those with oligodendrioglial tumors (27.3%). Our results indicate a possible relation between GBM formation and CCDN1 genotype

Cyclin D1 Gene G870A Variants and Primary Brain Tumors

Alterations of cyclin D1, one of the main regulators of the cell cycle, are known to be involved in various cancers. The CCDN1 G870A polymorphism causes production of a truncated variant with a shorter half-life and thus thought to impact the regulatory effect of CCDN1. The aim of the present study was to contribute to existing results to help to determine the prognostic value of this specific gene variant and evaluate the role of CCDN1 G870A polymorphism in brain cancer susceptibility. A Turkish study group including 99 patients with primary brain tumors and 155 healthy controls were examined. Genotypes were determined by polymerase chain reaction-restriction fragment length polymorphism analysis. The CCDN1 genotype frequencies in meningioma, glioma and control cases were not significantly different (p>0.05). No significant association was detected according to clinical parameters or tumor characteristics; however, a higher frequency of AG genotype was recorded within patients with astrocytic or oligoastrocytic tumors. A significant association between AG genotype and gliobilastoma multiforme (GBM) was recorded within the patients with glial tumors (p value=0.048 OR: 1.87 CI% 1.010-3.463). According to tumor characteristics, no statistically significant difference was detected within astrocytic, oligoasltrocytic tumors and oligodentrioglias. However, patients with astrocytic astrocytic or oligoastrocytic tumors showed a higher frequency of AG genotype (50%) when compared to those with oligodendrioglial tumors (27.3%). Our results indicate a possible relation between GBM formation and CCDN1 genotype

Use of PET-CT for the assessment of treatment results in patients with sarcoidosis

Background and aim Sarcoidosis is a multisystem disease of unknown origin. Determining the involvement and the response to the treatment is important. The aim of this study was to identify the effects of methylprednisolone and indomethacine on metabolic activity and pulmonary function test parameters in patients with sarcoidosis