15 research outputs found
Functional and Nutritional Properties of Some Turkish Traditional Foods
WOS: 00047765370000
Traditional Foods in Turkey: General and Consumer Aspects
WOS: 00037653250000
Encapsulation of Cumin (Cuminum cyminum L.) Seed Essential Oil in the Chickpea Protein–Maltodextrin Matrix
Isoelectrically precipitated chickpea protein isolate
(CPI) and
its combination with maltodextrin (MD) were investigated for the ability
to form and stabilize cumin seed oil emulsions. Solubility, net surface
charge, emulsion activity/stability indices, and creaming stability
of CPI at a pH of 3.0–9.0 were evaluated. Optimum conditions
for minimum cream separation were identified as: 0.19% CPI and 6.83%
oil concentrations. Cumin (Cuminum cyminum L.) seed essential oil was microencapsulated within the CPI–MD
matrix via spray drying. Effects of CPI–MD matrix formulation
on the physicochemical characteristics and volatile composition of
the microencapsules were investigated. CPI–MD matrices had
positive effects on microcapsule properties such as relatively lower
surface oil, higher encapsulation efficiency (EE), and oil retention.
Approximately 86.6–96.4% oil retention and 90.9–98.4%
EE were achieved. Optimum conditions for maximized oil retention (92.9%)
and EE (98.6%) were identified as: 2.1% CPI, 14.8% essential oil,
and 35% MD. GC–MS analysis of microcapsules was carried out
to determine the changes in volatile composition during spray drying.
Cymene, α-pinene, β-pinene, sabinene, terpinene, terpineol,
phellandrene, and cumin aldehyde were determined as the major components.
Optimized design showed the highest EE and minimal changes in the
volatile composition of cumin seed essential oil
Regulation of signal transduction cascades by Pterostilbenes in different cancers: Is it a death knell for oncogenic pathways
Interdisciplinary research has revolutionized the field of medicine and we have witnessed exponential increase in the high-impact research in past few decades. However, the road to this burgeoning research field is obstacle-ridden because of intratumor heterogeneity, loss of apoptosis and dysregulation of spatio-temporally controlled signaling pathways. Ground-breaking findings obtained through genetic, genomic and proteomic studies have considerably improved our concepts related to the complexity of protein network and excitingly, discovery of miRNAs has added another layer of intricacy to quantitatively regulated gene networks. In this review, we chronicle the milestone achievements and discuss how Pterostilbenes effectively regulated different cellular pathways. We have provided detailed mechanistic insights related to regulation of JAK-STAT signaling, Notch pathway, Wnt mediated intracellular signaling by pterostilbene. Underlying mechanisms about regulation of PI3K/AKT and MAPK pathways by pterostilbene in different cancers. Regulation of Metastasis-associated protein 1 (MTA1) proteins and Human telomerase reverse transcriptase (hTERT) in cancer cells by pterostilbene. Pterostilbene has also been reported to modulate the expression of various oncogenic and tumor suppressor microRNAs in cancer cells. Better and sharper comprehension of the concepts associated with the modes of action of pterostilbene in different cancers will be useful in identification of cancers which can be efficiently targeted by pterostilbene
Regulation of signal transduction cascades by Pterostilbenes in different cancers: Is it a death knell for oncogenic pathways
Interdisciplinary research has revolutionized the field of medicine and we have witnessed exponential increase in the high-impact research in past few decades. However, the road to this burgeoning research field is obstacle-ridden because of intratumor heterogeneity, loss of apoptosis and dysregulation of spatio-temporally controlled signaling pathways. Ground-breaking findings obtained through genetic, genomic and proteomic studies have considerably improved our concepts related to the complexity of protein network and excitingly, discovery of miRNAs has added another layer of intricacy to quantitatively regulated gene networks. In this review, we chronicle the milestone achievements and discuss how Pterostilbenes effectively regulated different cellular pathways. We have provided detailed mechanistic insights related to regulation of JAK-STAT signaling, Notch pathway, Wnt mediated intracellular signaling by pterostilbene. Underlying mechanisms about regulation of PI3K/AKT and MAPK pathways by pterostilbene in different cancers. Regulation of Metastasis-associated protein 1 (MTA1) proteins and Human telomerase reverse transcriptase (hTERT) in cancer cells by pterostilbene. Pterostilbene has also been reported to modulate the expression of various oncogenic and tumor suppressor microRNAs in cancer cells. Better and sharper comprehension of the concepts associated with the modes of action of pterostilbene in different cancers will be useful in identification of cancers which can be efficiently targeted by pterostilbene