Effects of Some Selected Macro-Economic Indicators on Exchange Rates (1986-2019)

Background: The foreign exchange market plays a significant role in the development of a country and the stability of her currency in recent years. Objectives: This article reports the effect of macro-economic indicators on foreign exchange parallel markets for a period between 1986 – 2019. Methods: The macro-economic indicators used were inflation rate, demand for money, the supply of money, OPEC crude oil and the real GDP growth with the dependency of the foreign exchange market. The data for this project was extracted from the publication of the Statistics Unit of the Central Bank of Nigeria in recent years. Multiple Linear Regression was used with special attention on Multicollinearity, Serial Correlation and Heteroscedasticity. The coefficient of determination value of 0.740 shows that the demand for money, the supply of money, OPEC crude oil and the real GDP growth accounted for over 74 percent of the variation in the exchange rate in Nigeria between the years 1986 and 2019. Results: It was discovered from the findings that, money supply into the circulation determines the foreign exchange rate. And it was also discovered that the money supply has a high dependency ratio on the exchange rate among other macro-economic indicators. Thus, the reduced model is a result of the insignificancy of other variables while only variable two (supply of money) is significant. Conclusions: The use of a flexible exchange rate had eliminated the over-valuation of the naira. The parallel market premium has also been narrowed from 600 percent in 1986 to about 11.0 percent in 2018. These were attributed to the weak and import-dependent production structure of the economy. The suggested solution was articulated towards increasing foreign exchange inflows, reducing demand, as well as reforming the foreign exchange market to evolve a more realistic exchange rate for the naira.  Keywords: Multiple Linear Regression, Macro-Economic Indicators, Exchange Rate, Multicollinearity, Serial Correlation and Heteroscedasticit

Effect of thermo-oxidized soybean oil on growth rate and skeletal muscle enzyme activities in rats

Fresh and thermooxidized soybean oil diets were fed to rats for six weeks at two supplementation levels (5% and 15%). Rats fed with thermooxidized oil showed growth depression probably as a result of gross accumulation of decomposition products in the gut of the rats thereby reducing intestinal absorption. Alkaline Phosphatase (ALP) and Acid Phosphatase (ACP) were assayed in the skeletal muscle of the rats. Significant decrease in activity of the enzymes was recorded starting from the second week till the end of the feeding period in the rats fed with 15% thermooxidized oil diet. The decrease in activity of the enzymes might be due to cellular damage caused by peroxides and other products of heated fat which might have inhibited the synthesis of the enzymes or allowed them to leak out of the cell. Analysis of protein content in the skeletal muscle of rats after the feeding experiment shows no significant changes. This study suggests that prolonged consumption of thermally heated Soybean oil at high level could be toxic to the living system

Kidney and Liver Function Parameters in Alloxan-Induced Diabetic Rats Treated with Aloe Barbadensis Juice Extract

Aloe barbadensis juice extract has been reported to possess hypoglycaemic property but the effects of its use on kidney and liver functions in diabetic animals have not been well investigated. This study investigated some biochemical parameters in the liver and kidney of alloxan-induced diabetic rats treated with Aloe barbadensis juice extract. Alloxan-induced diabetic rats were administered orally with Aloe barbadensis juice extract for seven days after which some biochemical indices in the serum, liver and kidney were measured and compared with the control. Serum alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), urea and creatinine of untreated diabetic group and treated diabetic groups were significantly elevated when compared with the normal control group with no significant changes in the levels of the enzymes in the liver and kidney. There were no significant changes (p>0.05) in the serum levels of Na+ and K+ in untreated diabetic group and treated diabetic groups when compared with the normal control rats which are not diabetic. These results suggest that administration of aqueous extract of Aloe barbadensis to diabetic rats did not have any adverse effect on the liver and kidney functions in rats showing that the extract is not toxic to man. Keywords: Aloe barbadensis, Alloxan, Liver function, Kidney function, Diabetic rats

Physico-chemical characteristics of Anopheles breeding sites: Impact on fecundity and progeny development

Mosquitoes exploit almost all types of aquatic habitats for breeding. Prevailing physicochemical parameters in these habitats are important factors for survival and development of mosquito. Here, six water samples from Atlantic Ocean, River, well, distilled (control), rain and borehole water were used to culture Anopheline eggs collected from pure bred of Kisimu species. The development of eggs to 1st, 2nd, 3rd and 4th instars larval, pupal and adult stages were observed from day 1 to 6 using six replicates of each water sample. The number of eggs laid (fecundity) by the emerged adults were estimated using counting microscope. Level of development in emerged adults was determined using the wing size. The analysis of the physicochemical parameters of the water samples was carried out in the Nigerian Institute of Marine and Oceanography. The physicochemical characteristics were compared with the rates of development and fecundity of the Anopheline species. Statistical analysis using ANOVA indicates no significant difference (P > 0.05) in the hatchability of the eggs. However, the rates of larval development to pupal stage and subsequent adult emergence showed a level of significant difference (P 0.05). This study provides information on mosquito ecology in relation to breeding habitat which may have bearing on vector population and distribution as well as malaria transmission in a particular area

Investigation of the Perception of Climate Change among Arable Crop Farmers in Akinyele Local Government Area of Oyo State, Nigeria

This study was designed to investigate the perception of climate change among arable crop farmers in Akinyele local government area of Oyo state, Nigeria using a well-structured questionnaire for data acquisition. Descriptive and inferential (chi-square) statistics were used to analyze the data.. The study revealed that majority of the respondents (50.8%) were between the ages of 40-49years and majority of them (85.8%) are married with household size of 7-10 persons. The study further revealed that (33.3%) of the respondents had no formal education while, (42.5%) of the respondents had a farming experience of 16years and above. However, it also shows that majority of the respondents are aware of the effect and causes of climate change. Significant association exists between marital status (x2=68.426, P=0.000), family size (X2=25.777, P=0.012) and perceived effect of climate change. The study therefore recommended that the government and extension agents should enlighten the women farmers more about climate change and should also help in making them adapt excellently to climate change

Real-world effectiveness and costs of vertical oscillatory pressure manipulation for low back pain

Introduction. Real-world evidence studies using routinely collected data, such as patient clinical records, are innovative ways of generating insight into the effectiveness of healthcare interventions. This study examined the effectiveness of vertical oscil-latory pressure (VOP) on selected clinical outcomes for patients with low back pain (LBP) using routinely collected data. Methods. Retrospective analysis was carried out on the medical records of patients diagnosed with LBP in a tertiary hospital in south-west Nigeria over a 10-year period. Clinical outcomes (pain intensity and functional disability) in patients who received VOP (n = 201) for their LBP were compared with controls that had traditional physiotherapy (TP) (n = 138) in a routine clinical setting. Total costs of intervention were estimated in terms of direct and indirect costs. Results. There were significant differences within group (from baseline to 4th and 8th week of intervention) for the VOP group in pain intensity (p = 0.001) and functional disability (p = 0.001). However, TP group showed no significant differences in pain intensity and functional disability across baseline and week 8 of the study. There was a significant difference in pain intensity (2.95 ± 1.38 vs. 4.16 ± 2.48; p = 0.013) between VOP and TP at week eight. A higher direct and indirect costs associated with VOP compared with TP (both p = 0.042). Conclusions. The findings of this study suggest that VOP is an effective intervention for LBP in the ‘real-world’. VOP is more effective compared to TP on its effect on pain intensity over time

Changes in mediators of inflammation and pro-thrombosis after 12 months of dietary modification in adults with metabolic syndrome.

Objective: This study evaluated the effects of a 12-month dietary modification on indices of inflammation and pro-thrombosis in adults with metabolic syndrome (MS). Materials and methods: This longitudinal study involved 252 adults with MS recruited from the Bodija market, Ibadan and its environs. Participants were placed on 20%, 30% and 50% calories obtained from protein, total fat and carbohydrate respectively and were followed up monthly for 12 months. Anthropometry and blood pressure were measured using standard methods. Fasting plasma glucose (FPG), total cholesterol (TC), triglycerides (TG), high density lipoprotein-cholesterol (HDL-C), fibrinogen, plasminogen activator inhibitor-1 (PAI-1)], interleukin-6 (IL-6) and interleukin-10 (IL-10) were measured using spectrophotometric methods and ELISA as appropriate. Data was analysed using ANCOVA, Student\u2019s t-test, Mann-Whitney U and Wilcoxon signed-rank tests. P-values less than 0.05 were considered significant. Results: After 6 months of dietary modification, there was a significant reduction in waist circumference (WC), while the levels of HDL-C, fibrinogen and PAI-1 were significantly increased when compared with the corresponding baseline values. However, WC and fibrinogen reduced significantly, while HDL-C and IL-10 significantly increased after 12 months of dietary modification as compared with the respective baseline values. Conclusion: Long-term regular dietary modification may be beneficial in ameliorating inflammation and pro-thrombosis in metabolic syndrome

The dominant Anopheles vectors of human malaria in Africa, Europe and the Middle East: occurrence data, distribution maps and bionomic précis

<p>Abstract</p> <p>Background</p> <p>This is the second in a series of three articles documenting the geographical distribution of 41 dominant vector species (DVS) of human malaria. The first paper addressed the DVS of the Americas and the third will consider those of the Asian Pacific Region. Here, the DVS of Africa, Europe and the Middle East are discussed. The continent of Africa experiences the bulk of the global malaria burden due in part to the presence of the <it>An. gambiae </it>complex. <it>Anopheles gambiae </it>is one of four DVS within the <it>An. gambiae </it>complex, the others being <it>An. arabiensis </it>and the coastal <it>An. merus </it>and <it>An. melas</it>. There are a further three, highly anthropophilic DVS in Africa, <it>An. funestus</it>, <it>An. moucheti </it>and <it>An. nili</it>. Conversely, across Europe and the Middle East, malaria transmission is low and frequently absent, despite the presence of six DVS. To help control malaria in Africa and the Middle East, or to identify the risk of its re-emergence in Europe, the contemporary distribution and bionomics of the relevant DVS are needed.</p> <p>Results</p> <p>A contemporary database of occurrence data, compiled from the formal literature and other relevant resources, resulted in the collation of information for seven DVS from 44 countries in Africa containing 4234 geo-referenced, independent sites. In Europe and the Middle East, six DVS were identified from 2784 geo-referenced sites across 49 countries. These occurrence data were combined with expert opinion ranges and a suite of environmental and climatic variables of relevance to anopheline ecology to produce predictive distribution maps using the Boosted Regression Tree (BRT) method.</p> <p>Conclusions</p> <p>The predicted geographic extent for the following DVS (or species/suspected species complex*) is provided for Africa: <it>Anopheles </it>(<it>Cellia</it>) <it>arabiensis</it>, <it>An. </it>(<it>Cel.</it>) <it>funestus*</it>, <it>An. </it>(<it>Cel.</it>) <it>gambiae</it>, <it>An. </it>(<it>Cel.</it>) <it>melas</it>, <it>An. </it>(<it>Cel.</it>) <it>merus</it>, <it>An. </it>(<it>Cel.</it>) <it>moucheti </it>and <it>An. </it>(<it>Cel.</it>) <it>nili*</it>, and in the European and Middle Eastern Region: <it>An. </it>(<it>Anopheles</it>) <it>atroparvus</it>, <it>An. </it>(<it>Ano.</it>) <it>labranchiae</it>, <it>An. </it>(<it>Ano.</it>) <it>messeae</it>, <it>An. </it>(<it>Ano.</it>) <it>sacharovi</it>, <it>An. </it>(<it>Cel.</it>) <it>sergentii </it>and <it>An. </it>(<it>Cel.</it>) <it>superpictus*</it>. These maps are presented alongside a bionomics summary for each species relevant to its control.</p

Radiologic Features of Chronic Rhinosinusitis in Sagamu

To present the plain X ray features of chronic rhinosinusitis seen at Olabisi Onabanjo University Teaching Hospital, Sagamu. Retrospective analysis of the plain X-rays of the paranasal sinuses of patients with clinical features of rhinosinusitis of at least 12 weeks duration, managed between 2002 and 2006. The data was analysed using SPSS version 10.0 and the results presented in simple descriptive form. There were one hundred and ten (110) patients M: F =1:1.04 The average age was 38.92 years The duration of symptoms ranged from 3 months (13weeks) to 16.25 years, (average of 2.81 years). The plain X rays were reported as normal in 29.09% while the remaining 70.91% had abnormal findings. 85.90% with positive radiological findings had demonstrable features in their nasal cavities. The maxillary sinus had the highest proportion of abnormalities (70.51%) while sphenoid sinus was the least (0%) involved sinus. 21.79% of the patients had multisinusitis and 5.13% had pansinusitis. The common radiological features seen in the sinuses were haziness, mucosal thickening (maxillary), and opacities (ethmoidal and frontal). Plain X rays remain relevant in the evaluation of patients with suspected chronic rhinosinusitis in the developing countries at least as a preliminary investigation. Keywords: Chronic rhinosinusitis, Paranasal sinuses, Plain X-rays, Radiologic features Nigerian Medical Practitioner Vol. 54 (2) 2008: pp. 28-3