79 research outputs found
Low-cost point-focus solar concentrator, phase 1
The results of the preliminary design study for the low cost point focus solar concentrator (LCPFSC) development program are presented. A summary description of the preliminary design is given. The design philosophy used to achieve a cost effective design for mass production is described. The concentrator meets all design requirements specified and is based on practical design solutions in every possible way
Recent Accumulation Variability in Northwest Greenland from Ground-Penetrating Radar and Shallow Cores along the Greenland Inland Traverse
Accumulation is a key parameter governing the mass balance of the Greenland ice sheet. Several studies have documented the spatial variability of accumulation over wide spatial scales, primarily using point data, remote sensing or modeling. Direct measurements of spatially extensive, detailed profiles of accumulation in Greenland, however, are rare. We used 400 MHz ground-penetrating radar along the 1009 km route of the Greenland Inland Traverse from Thule to Summit during April and May of 2011, to image continuous internal reflecting horizons. We dated these horizons using ice-core chemistry at each end of the traverse. Using density profiles measured along the traverse, we determined the depth to the horizons and the corresponding water-equivalent accumulation rates. The measured accumulation rates vary from ~0.1 m w.e. a–1 in the interior to ~0.7 m w.e. a–1 near the coast, and correspond broadly with existing published model results, though there are some excursions. Comparison of our recent accumulation rates with those collected along a similar route in the 1950s shows a ~10% increase in accumulation rates over the past 52 years along most of the traverse route. This implies that the increased water vapor capacity of warmer air is increasing accumulation in the interior of Greenland
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Neptunium retardation with tuffs and groundwaters from Yucca Mountain
The retardation of neptunium was studied using batch sorption and column techniques. Pure mineral separates, tuffs and groundwaters from Yucca Mountain were used for these experiments. Our results indicate that Np sorption increases rapidly as the pH of the water increases in cases where surface complexation is thought w be the dominant sorption mechanism. Oxide minerals (such as hematite) sorb Np strongly; therefore, these minerals even at trace levels in Yucca Mountain tuffs can result in significant Np retardation. Neptunium in groundwaters from Yucca Mountain exhibited a significant amount of sorption onto quartz. Neptunium sorption onto quartz is important because of the large quantity of silica in the tuffs. Elution of neptunium solutions in groundwater through columns made of crushed tuff yielded sorption coefficients that agree with the sorption results obtained using batch sorption techniques. Agreement between batch and column experiments indicates a neptunium sorption mechanism that is linear, reversible, and instantaneous
An anatomic gene expression atlas of the adult mouse brain
Studying gene expression provides a powerful means of understanding structure-function relationships in the nervous system. The availability of genome-scale in situ hybridization datasets enables new possibilities for understanding brain organization based on gene expression patterns. The Anatomic Gene Expression Atlas (AGEA) is a new relational atlas revealing the genetic architecture of the adult C57Bl/6J mouse brain based on spatial correlations across expression data for thousands of genes in the Allen Brain Atlas (ABA). The AGEA includes three discovery tools for examining neuroanatomical relationships and boundaries: (1) three-dimensional expression-based correlation maps, (2) a hierarchical transcriptome-based parcellation of the brain and (3) a facility to retrieve from the ABA specific genes showing enriched expression in local correlated domains. The utility of this atlas is illustrated by analysis of genetic organization in the thalamus, striatum and cerebral cortex. The AGEA is a publicly accessible online computational tool integrated with the ABA (http://mouse.brain-map.org/agea)
Greenland ice sheet surface mass loss: recent developments in observation and modeling
Surface processes currently dominate Greenland ice sheet (GrIS) mass loss. We review recent developments in the observation and modelling of GrIS surface mass balance (SMB), published after the July 2012 deadline for the Fifth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC AR5). Since IPCC AR5 our understanding of GrIS SMB has further improved, but new observational and model studies have also revealed that temporal and spatial variability of many processes are still
poorly quantified and understood, e.g. bio-albedo, the formation of ice lenses and their impact on lateral meltwater transport, heterogeneous vertical meltwater transport (‘piping’), the impact of atmospheric circulation changes and mixed-phase clouds on the surface energy balance and the magnitude of turbulent heat exchange over rough ice surfaces. As a result, these processes are only schematically or not at all included in models that are currently used to assess and predict future GrIS surface mass loss
The Time Machine: Leisure Science (Fiction) and Futurology
There is a long, underlying presence of futurology—attempts to predict the future based on current or past events—throughout much of the leisure literature. On the occasion of the 40th anniversary of Leisure Sciences, I build on the work of futures scholars (e.g., Adam, 2008; Harrison, 2015) to explore how past ideas about the future have shaped the present. I revisit H. G. Wells's (1895) classic science fiction novel The Time Machine in view of recent trends and recurring debates (e.g., cybernation, (un)employment, the “leisure society,” and Universal Basic Income) that are (or were) forecast to shape the future. Throughout, I argue that the ways that leisure scholars envision the future have significant impact on the actions of the field and its practitioners today
CAR-associated vesicular transport of an adenovirus in motor neuron axons.
Axonal transport is responsible for the movement of signals and cargo between nerve termini and cell bodies. Pathogens also exploit this pathway to enter and exit the central nervous system. In this study, we characterised the binding, endocytosis and axonal transport of an adenovirus (CAV-2) that preferentially infects neurons. Using biochemical, cell biology, genetic, ultrastructural and live-cell imaging approaches, we show that interaction with the neuronal membrane correlates with coxsackievirus and adenovirus receptor (CAR) surface expression, followed by endocytosis involving clathrin. In axons, long-range CAV-2 motility was bidirectional with a bias for retrograde transport in nonacidic Rab7-positive organelles. Unexpectedly, we found that CAR was associated with CAV-2 vesicles that also transported cargo as functionally distinct as tetanus toxin, neurotrophins, and their receptors. These results suggest that a single axonal transport carrier is capable of transporting functionally distinct cargoes that target different membrane compartments in the soma. We propose that CAV-2 transport is dictated by an innate trafficking of CAR, suggesting an unsuspected function for this adhesion protein during neuronal homeostasis
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