The formation of strategies for effective management of business environment of the region

This study is aimed to explore the opportunities of creating conditions which is necessary for successful development of small and medium enterprises of Russia and the Belgorod region in particular in the chemical industry of leather and footwear sector. The system of criteria for the assessment of the entrepreneurial activity of small and medium enterprises is proposed. The directions of development of small and medium enterprises in the chemical industry of leather and footwear sector are designedyesБелгородский государственный университе

The innovation subsystem development level evaluation of the regional social-economic systems

The innovation subsystem development level evaluation of the regional social-economic systems / Y. V. Nikulina, J. V. Lyshchikova, A. V. Orlova et al. // International Business Management. - 2016. - Vol.10,N16.-P. 3427-3431. - Refer.: p. 3431.The stusy analyzes the methodological approaches to the identification and assessment of the innovation potential of the regional socio-economic systems. The system of indicators of the region's innovative capacity is formed. The assessment and ranging of regional social and economic systems of Russia on a level of development of innovative potential is carried ou

Controlling the topological sector of magnetic solitons in exfoliated Cr1/3_{1/3}NbS2_2 crystals

We investigate manifestations of topological order in monoaxial helimagnet Cr$_{1/3}$NbS$_2$ by performing transport measurements on ultra-thin crystals. Upon sweeping the magnetic field perpendicularly to the helical axis, crystals thicker than one helix pitch (48 nm) but much thinner than the magnetic domain size ($\sim$1 $\mu$m) are found to exhibit sharp and hysteretic resistance jumps. We show that these phenomena originate from transitions between topological sectors with different number of magnetic solitons. This is confirmed by measurements on crystals thinner than 48 nm --in which the topological sector cannot change-- that do not exhibit any jump or hysteresis. Our results show the ability to deterministically control the topological sector of finite-size Cr$_{1/3}$NbS$_2$ and to detect inter-sector transitions by transport measurements.Comment: 7 pages, 8 figure

Theory of Orbital Ordering, Fluctuation and Resonant X-ray Scattering in Manganites

A theory of resonant x-ray scattering in perovskite manganites is developed by applying the group theory to the correlation functions of the pseudospin operators for the orbital degree of freedom. It is shown that static and dynamical informations of the orbital state are directly obtained from the elastic, diffuse and inelastic scatterings due to the tensor character of the scattering factor. We propose that the interaction and its anisotropy between orbitals are directly identified by the intensity contour of the diffuse scattering in the momentum space.Comment: 4 pages, 1 figur

Clinical and epidemiological features of enterovirus meningitis in children in 2018

Enteroviral meningitis occupies a leading place in the etiological structure of meningitis. The paper presents a retrospective analysis of 250 medical histories of children with enterovirus meningitis. There is the highest incidence of enterovirus meningitis in the age group of children from 7 to 14 years. Meningitis proceeded in a moderate form, without deaths and residual effects, but in 2 cases there was a severe course of the disease. Enterovirus serous meningitis can be reported as both sporadic diseases and infectious outbreaks.Энтеровирусные менингиты занимают ведущее место в этиологической структуре менингитов. В работе представлен ретроспективный анализ 250 историй болезни детей с энтеровирусными менингитами. Отмечалась наиболее высокая заболеваемость энтеровирусными менингитами в возрастной группе детей от 7 до 14 лет. Менингит протекал в среднетяжелой форме, без летальных исходов и остаточных явлений, однако в 2 случаях отмечена тяжелая форма инфекции. Энтеровирусные серозные менингиты могут регистрироваться как в виде спорадических заболеваний, так и в виде инфекционных вспышек

Influence of spin structures and nesting on Fermi surface and a pseudogap anisotropy in t-t'-U Hubbard model

Influence of two type of spin structures on the form of the Fermi surface (FS) and a photoemission intensity map is studied for t-t'-U Hubbard model. Mean field calculations are done for the stripe phase and for the spiral spin structure. It is shown, that unlike a case of electron doping, the hole-doped models are unstable with respect to formation of such structures. The pseudogap anisotropies are different for h- and e- doping. In accordance with ARPES data for La2SrxCuO4 the stripe phase is characterized by quasi-one-dimensional segments of FS at k=(\pi,0) and by suppression of spectral weight in diagonal direction. It is shown that spiral structures display the polarisation anisotropy: different segments of FS correspond to electros with different spin polarisations.Comment: 12 pages, 4 figure

Enterovirus meningitis due to new coronavirus infection in children

The purpose of the study was to reveal the clinical and laboratory features of enteroviral meningitis in children with new coronavirus infection.Цель исследования — Выявить клинические и лабораторные особенности энтеровирусных менингитов у детей, протекающих на фоне новой коронавирусной инфекции (НКВИ)

Variations in O-antigen biosynthesis and O-acetylation associated with altered phage sensitivity in Escherichia coli 4s

© 2015, American Society for Microbiology. The O polysaccharide of the lipopolysaccharide (O antigen) of Gram-negative bacteria often serves as a receptor for bacteriophages that can make the phage dependent on a given O-antigen type, thus supporting the concept of the adaptive significance of the O-antigen variability in bacteria. The O-antigen layer also modulates interactions of many bacteriophages with their hosts, limiting the access of the viruses to other cell surface receptors. Here we report variations of O-antigen synthesis and structure in an environmental Escherichia coli isolate, 4s, obtained from horse feces, and its mutants selected for resistance to bacteriophage G7C, isolated from the same fecal sample. The 4s O antigen was found to be serologically, structurally, and genetically related to the O antigen of E. coli O22, differing only in side-chain α-D-glucosylation in the former, mediated by a gtr locus on the chromosome. Spontaneous mutations of E. coli 4s occurring with an unusually high frequency affected either O-antigen synthesis or O-acetylation due to the inactivation of the gene encoding the putative glycosyltransferase WclH or the putative acetyltransferase WclK, respectively, by the insertion of IS1-like elements. These mutations induced resistance to bacteriophage G7C and also modified interactions of E. coli 4s with several other bacteriophages conferring either resistance or sensitivity to the host. These findings suggest that O-antigen synthesis and O-acetylation can both ensure the specific recognition of the O-antigen receptor following infection by some phages and provide protection of the host cells against attack by other phages

第一外科この1年

© 2015, American Society for Microbiology. The O polysaccharide of the lipopolysaccharide (O antigen) of Gram-negative bacteria often serves as a receptor for bacteriophages that can make the phage dependent on a given O-antigen type, thus supporting the concept of the adaptive significance of the O-antigen variability in bacteria. The O-antigen layer also modulates interactions of many bacteriophages with their hosts, limiting the access of the viruses to other cell surface receptors. Here we report variations of O-antigen synthesis and structure in an environmental Escherichia coli isolate, 4s, obtained from horse feces, and its mutants selected for resistance to bacteriophage G7C, isolated from the same fecal sample. The 4s O antigen was found to be serologically, structurally, and genetically related to the O antigen of E. coli O22, differing only in side-chain α-D-glucosylation in the former, mediated by a gtr locus on the chromosome. Spontaneous mutations of E. coli 4s occurring with an unusually high frequency affected either O-antigen synthesis or O-acetylation due to the inactivation of the gene encoding the putative glycosyltransferase WclH or the putative acetyltransferase WclK, respectively, by the insertion of IS1-like elements. These mutations induced resistance to bacteriophage G7C and also modified interactions of E. coli 4s with several other bacteriophages conferring either resistance or sensitivity to the host. These findings suggest that O-antigen synthesis and O-acetylation can both ensure the specific recognition of the O-antigen receptor following infection by some phages and provide protection of the host cells against attack by other phages

Dzyaloshinskii--Moriya interaction: How to measure its sign in weak ferromagnetics?

Three experimental techniques sensitive to the sign of the Dzyaloshinskii--Moriya interaction are discussed: neutron diffraction, Moessbauer gamma-ray diffraction, and resonant x-ray scattering. Classical examples of hematite (alpha-Fe2O3) and MnCO3 crystals are considered in detailComment: 5 pages, 1 figure; to be published in JETP Letter