Experience of using immuno-therapy in treatment of chronic generalized periodontitis

The application of immunomodulator Gepon in the treatment of chronic generalized periodontitis can improve the quality of care, reduce the time of preoperative preparation of up to 10 days (in the traditional treatment 14-16 days), rapid postoperative rehabilitation of patients and to achieve stable remission in 82% of patients with chronic periodontitis easy degree and 77% with moderate periodontitis after 6 months of observatio

Self-trapped bidirectional waveguides in a saturable photorefractive medium

We introduce a time-dependent model for the generation of joint solitary waveguides by counter-propagating light beams in a photorefractive crystal. Depending on initial conditions, beams form stable steady-state structures or display periodic and irregular temporal dynamics. The steady-state solutions are non-uniform in the direction of propagation and represent a general class of self-trapped waveguides, including counterpropagating spatial vector solitons as a particular case.Comment: 4 pages, 5 figure

Bose-Einstein Condensates in Optical Lattices: Band-Gap Structure and Solitons

We analyze the existence and stability of spatially extended (Bloch-type) and localized states of a Bose-Einstein condensate loaded into an optical lattice. In the framework of the Gross-Pitaevskii equation with a periodic potential, we study the band-gap structure of the matter-wave spectrum in both the linear and nonlinear regimes. We demonstrate the existence of families of spatially localized matter-wave gap solitons, and analyze their stability in different band gaps, for both repulsive and attractive atomic interactions

Observation of non-Hermitian degeneracies in a chaotic exciton-polariton billiard

This research was supported by the Australian Research Council, the ImPACT Program of the Council for Science, Technology and Innovation (Cabinet Office, Government of Japan), the RIKEN iTHES Project, the MURI Center for Dynamic Magneto-Optics, a Grant-in-Aid for Scientific Research (type A), and the State of Bavaria.Exciton-polaritons are hybrid light-matter quasiparticles formed by strongly interacting photons and excitons (electron-hole pairs) in semiconductor microcavities. They have emerged as a robust solid-state platform for next-generation optoelectronic applications as well as for fundamental studies of quantum many-body physics. Importantly, exciton-polaritons are a profoundly open (that is, non-Hermitian) quantum system, which requires constant pumping of energy and continuously decays, releasing coherent radiation. Thus, the exciton-polaritons always exist in a balanced potential landscape of gain and loss. However, the inherent non-Hermitian nature of this potential has so far been largely ignored in exciton-polariton physics. Here we demonstrate that non-Hermiticity dramatically modifies the structure of modes and spectral degeneracies in exciton-polariton systems, and, therefore, will affect their quantum transport, localization and dynamical properties. Using a spatially structured optical pump, we create a chaotic exciton-polariton billiard-a two-dimensional area enclosed by a curved potential barrier. Eigenmodes of this billiard exhibit multiple non-Hermitian spectral degeneracies, known as exceptional points. Such points can cause remarkable wave phenomena, such as unidirectional transport, anomalous lasing/absorption and chiral modes. By varying parameters of the billiard, we observe crossing and anti-crossing of energy levels and reveal the non-trivial topological modal structure exclusive to non-Hermitian systems. We also observe mode switching and a topological Berry phase for a parameter loop encircling the exceptional point. Our findings pave the way to studies of non-Hermitian quantum dynamics of exciton-polaritons, which may uncover novel operating principles for polariton-based devices.PostprintPeer reviewe

Josephson dynamics for coupled polariton modes under the atom-field interaction in the cavity

We consider a new approach to the problem of Bose-Einstein condensation (BEC) of polaritons for atom-field interaction under the strong coupling regime in the cavity. We investigate the dynamics of two macroscopically populated polariton modes corresponding to the upper and lower branch energy states coupled via Kerr-like nonlinearity of atomic medium. We found out the dispersion relations for new type of collective excitations in the system under consideration. Various temporal regimes like linear (nonlinear) Josephson transition and/or Rabi oscillations, macroscopic quantum self-trapping (MQST) dynamics for population imbalance of polariton modes are predicted. We also examine the switching properties for time-averaged population imbalance depending on initial conditions, effective nonlinear parameter of atomic medium and kinetic energy of low-branch polaritons.Comment: 10 pages, 6 postscript figures, uses svjour.cl

Stable vortex and dipole vector solitons in a saturable nonlinear medium

We study both analytically and numerically the existence, uniqueness, and stability of vortex and dipole vector solitons in a saturable nonlinear medium in (2+1) dimensions. We construct perturbation series expansions for the vortex and dipole vector solitons near the bifurcation point where the vortex and dipole components are small. We show that both solutions uniquely bifurcate from the same bifurcation point. We also prove that both vortex and dipole vector solitons are linearly stable in the neighborhood of the bifurcation point. Far from the bifurcation point, the family of vortex solitons becomes linearly unstable via oscillatory instabilities, while the family of dipole solitons remains stable in the entire domain of existence. In addition, we show that an unstable vortex soliton breaks up either into a rotating dipole soliton or into two rotating fundamental solitons.Comment: To appear in Phys. Rev.

Nonresonant spin selection methods and polarization control in exciton-polariton condensates

The authors would like to thank the State of Bavaria and the german research association (DFG) within the DFG project Schn1376 3-1 for financial support. E.A.O. acknowledges support by the Australian Research Council (ARC). A.N. acknowledges support from Icelandic Research Fund, Grant No. 196301-051 and from Russian Science Foundation, Grant No. 18-72-10110. T.H.H. gratefully acknowledges support by the Elite Network Bavaria within the doctoral training programme “Topological Insulators” (Tols 836315). Sample growth by S. Brodbeck, and technology support by M. Emmerling and A. Wolf is acknowledged. C. S. acknowledges discussions with T. Kiessling. T.C.H.L. was supported by the Singapore Ministry of Education Academic Research Fund Tier 2, Project No. MOE2017-T2-1-001.Bosonic condensates of exciton-polaritons are characterized by a well-defined pseudospin, which makes them attractive for quantum information schemes and spintronic applications, as well as the exploration of synthetic spin-orbit coupling. However, precise polarization control of coherent polariton condensates under nonresonant injection, the most important ingredient for such advanced studies, still remains a core challenge. Here, we address this problem and demonstrate unprecedented control of the pseudospin of an exciton-polariton condensate. The ultrafast stimulated scattering process allows the observation of completely spin-polarized condensates under highly nonresonant, circularly polarized excitation. This conservation of spin population translates, in the case of linearly polarized excitation, into an elliptically polarized emission. The degree of ellipticity can be controlled by varying the exciton-photon detuning and condensate density. Additionally, cavity engineering allows us to generate completely linearly polarized condensates with a deterministically chosen orientation. Our findings are of fundamental importance for the engineering and design of polaritonic devices that harness the spinor degree of freedom, such as chiral lasers, spin switches, and polaritonic topological insulator circuits.PostprintPeer reviewe

Resonant Generation of Topological Modes in Trapped Bose Gases

Trapped Bose atoms cooled down to temperatures below the Bose-Einstein condensation temperature are considered. Stationary solutions to the Gross-Pitaevskii equation (GPE) define the topological coherent modes, representing nonground-state Bose-Einstein condensates. These modes can be generated by means of alternating fields whose frequencies are in resonance with the transition frequencies between two collective energy levels corresponding to two different topological modes. The theory of resonant generation of these modes is generalized in several aspects: Multiple-mode formation is described; a shape-conservation criterion is derived, imposing restrictions on the admissible spatial dependence of resonant fields; evolution equations for the case of three coherent modes are investigated; the complete stability analysis is accomplished; the effects of harmonic generation and parametric conversion for the topological coherent modes are predicted. All considerations are realized both by employing approximate analytical methods as well as by numerically solving the GPE. Numerical solutions confirm all conclusions following from analytical methods.Comment: One reference modifie

Symmetry-breaking Effects for Polariton Condensates in Double-Well Potentials

We study the existence, stability, and dynamics of symmetric and anti-symmetric states of quasi-one-dimensional polariton condensates in double-well potentials, in the presence of nonresonant pumping and nonlinear damping. Some prototypical features of the system, such as the bifurcation of asymmetric solutions, are similar to the Hamiltonian analog of the double-well system considered in the realm of atomic condensates. Nevertheless, there are also some nontrivial differences including, e.g., the unstable nature of both the parent and the daughter branch emerging in the relevant pitchfork bifurcation for slightly larger values of atom numbers. Another interesting feature that does not appear in the atomic condensate case is that the bifurcation for attractive interactions is slightly sub-critical instead of supercritical. These conclusions of the bifurcation analysis are corroborated by direct numerical simulations examining the dynamics of the system in the unstable regime.MICINN (Spain) project FIS2008- 0484

From Coherent Modes to Turbulence and Granulation of Trapped Gases

The process of exciting the gas of trapped bosons from an equilibrium initial state to strongly nonequilibrium states is described as a procedure of symmetry restoration caused by external perturbations. Initially, the trapped gas is cooled down to such low temperatures, when practically all atoms are in Bose-Einstein condensed state, which implies the broken global gauge symmetry. Excitations are realized either by imposing external alternating fields, modulating the trapping potential and shaking the cloud of trapped atoms, or it can be done by varying atomic interactions by means of Feshbach resonance techniques. Gradually increasing the amount of energy pumped into the system, which is realized either by strengthening the modulation amplitude or by increasing the excitation time, produces a series of nonequilibrium states, with the growing fraction of atoms for which the gauge symmetry is restored. In this way, the initial equilibrium system, with the broken gauge symmetry and all atoms condensed, can be excited to the state, where all atoms are in the normal state, with completely restored gauge symmetry. In this process, the system, starting from the regular superfluid state, passes through the states of vortex superfluid, turbulent superfluid, heterophase granular fluid, to the state of normal chaotic fluid in turbulent regime. Both theoretical and experimental studies are presented.Comment: Latex file, 25 pages, 4 figure