The sustainability of communicative packaging concepts in the food supply chain. A case study: part 1. Life cycle assessment

Purpose In recent years, a new perspective for food packaging has emerged as a result of several issues like quality, safety, competitive prices or providing of useful information to consumers. This new perspective is called communicative packaging. Communicative packaging may influence consumers/companies on purchasing decisions. Since the environmental evaluation of such systems has not yet been performed, this paper is focused on the environmental evaluation of a flexible best-before-date (FBBD) communicative device on a packaging consumer unit and its implications on reducing environmental impacts related to fresh products. This consumer unit consists of a nanoclay-based polylactic acid tray filled with pork chops. Methods The environmental assessment of the consumer unit was made through life cycle assessment (LCA) using a cradle-to-gate approach. Environmental impacts were assessed according to the Eco-Indicator 99 v 2.1 methodology in Individualist (I) perspective. Results and discussion Several results were obtained from the LCA. With regard to environmental impacts of the FBBD, most of them were due to the paper substrate used for the manufacture of this communicative packaging concept as well as to the transports for delivering the components of the FBBD communicative device. On the other hand, when environmental impacts of packaging system with and without FBBD were compared, a large environmental load was detected for the system that has the communicative device affixed as a result of the higher weight of the package. However, the environmental load caused by the use of the FBBD was minimal in comparison with the total environmental load of the whole packaging system. On the contrary, the consumer unit that has the communicative device affixed showed less environmental burden than the consumer unit that has not affixed the device. This was due to the environmental benefits that the communicative device provides by reducing the amount of out-of-date packaged products at retailer outlets. Conclusions The use of a FBBD contributes to minimize environmental burdens related to the production, packaging and delivery of pork chops since it facilitates a dynamic control of out-of-date products even though the consumer unit with FBBD weighs 1 g more than the consumer unit that does not use the communicative device. Recommendations The results presented in this paper are estimated results of a specific case study for a prototype of communicative packaging device. Consequently, these results must be considered as a first approach according to future developments on communicative packaging

The sustainability of communicative packaging concepts in the food supply chain. A case study: part 2. Life cycle costing and sustainability assessment

This paper is the second part of a two-paper series dealing with the sustainability evaluation of a new communicative packaging concept. The communicative packaging concept includes a device that allows changing the expiry date of the product as function of temperature during transport and storage: a flexible best-before-date (FBBD). Such device was analysed in a consumer unit consisting of a nanoclay-based polylactic acid tray filled with pork chops. An economic assessment was made through the use of life cycle costing (LCC) methodology proposed by Bovea and Vidal (Resources, Conservation and Recycling Volume 41, Issue 2, May 2004, Pages 133-145) where both internal and external costs were considered. Furthermore, the social aspects were analysed using a contingent valuation (CV) of the willingness to pay (WTP). The sustainability assessment of FBBD was made through the combination of life cycle assessment (LCA) and LCC results, together with the CV of the WTP according to the method proposed by Bovea and Vidal. It was assumed that the use of the FBBD minimizes the food losses from 3.5% to 0.5%. LCC results show that internal costs related to pork chops and logistic supply chain life cycle represent more than 90% of life cycle cost. The use of FBBD communicative device could increase pork chop selling price between 0.01 and 0.1 a,not sign since the purchasing cost of this communicative device is included in this price. WTP results show that FBBD purchasing cost for consumer acceptance is estimated as 0.05 a,not sign/FBBD. Therefore, only pork chop selling price for scenarios 1 (0.05 a,not sign/device) and 3 (0.01 a,not sign/device) could be accepted by consumers. The most sustainable situation is reached when the cost of the FBBD is as less as possible (0.01 a,not sign). The use of FBBD communicative device has economic advantages for perishable products since it contributes to the increase in the economic savings due to the reduction of food losses. However, these economic savings represent a small percentage over pork chop selling price, and therefore, an FBBD price less than 0.02 a,not sign/device is required. If a lower price for the communicative device is reached, satisfying the WTP of consumers (0.05 a,not sign/FBBD), the communicative package will be much more sustainable. It is expected that the competitiveness of FBBD communicative device will be improved in the future. This might be accomplished by reducing FBBD production and distribution costs and increasing their social acceptance, providing more sustainable solutions

Large-scale calcium channel gene rearrangements in episodic ataxia and hemiplegic migraine: implications for diagnostic testing

Background: Episodic ataxia type 2 (EA2) and familial hemiplegic migraine type 1 (FHM1) are autosomal dominant disorders characterised by paroxysmal ataxia and migraine, respectively. Point mutations in CACNA1A, which encodes the neuronal P/Q-type calcium channel, have been detected in many cases of EA2 and FHM1. The genetic basis of typical cases without CACNA1A point mutations is not fully known. Standard DNA sequencing methods may miss large scale genetic rearrangements such as deletions and duplications. The authors investigated whether large scale genetic rearrangements in CACNA1A can cause EA2 and FHM1. Methods: The authors used multiplex ligation dependent probe amplification (MLPA) to screen for intragenic CACNA1A rearrangements. Results: The authors identified five previously unreported large scale deletions in CACNA1A in seven families with episodic ataxia and in one case with hemiplegic migraine. One of the deletions (exon 6 of CACNA1A) segregated with episodic ataxia in a four generation family with eight affected individuals previously mapped to 19p13. In addition, the authors identified the first pathogenic duplication in CACNA1A in an index case with isolated episodic diplopia without ataxia and in a first degree relative with episodic ataxia. Conclusions: Large scale deletions and duplications can cause CACNA1A associated channelopathies. Direct DNA sequencing alone is not sufficient as a diagnostic screening test

Circulating microRNAs in sera correlate with soluble biomarkers of immune activation but do not predict mortality in ART treated individuals with HIV-1 infection: A case control study

10.1371/journal.pone.0139981PLoS ONE1010e013998