592 research outputs found

    БистСмы контроля ΠΈ управлСния доступом ΠΊΠ°ΠΊ срСдство обСспСчСния бСзопасности ΠΎΠ±ΡŠΠ΅ΠΊΡ‚Π° Π·Π°Ρ‰ΠΈΡ‚Ρ‹

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    Под систСмами контроля ΠΈ управлСния доступом (Π‘ΠšΠ£Π”) ΠΏΠΎΠ½ΠΈΠΌΠ°ΡŽΡ‚ комплСкс тСхничСских срСдств ΠΈ ΠΎΡ€Π³Π°Π½ΠΈΠ·Π°Ρ†ΠΈΠΎΠ½Π½ΠΎ-мСтодичСских мСроприятий, ΠΎΠ±Π»Π°Π΄Π°ΡŽΡ‰ΠΈΡ… тСхничСской, ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΎΠ½Π½ΠΎΠΉ, ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΠ½ΠΎΠΉ ΠΈ эксплуатационной ΡΠΎΠ²ΠΌΠ΅ΡΡ‚ΠΈΠΌΠΎΡΡ‚ΡŒΡŽ.Access control and management subsystems (SKUD) are a set of technical tools and organizational and methodological measures that have technical, information, software and operational compatibility

    Cell organization in soft media due to active mechanosensing

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    Adhering cells actively probe the mechanical properties of their environment and use the resulting information to position and orient themselves. We show that a large body of experimental observations can be consistently explained from one unifying principle, namely that cells strengthen contacts and cytoskeleton in the direction of large effective stiffness. Using linear elasticity theory to model the extracellular environment, we calculate optimal cell organization for several situations of interest and find excellent agreement with experiments for fibroblasts, both on elastic substrates and in collagen gels: cells orient in the direction of external tensile strain, they orient parallel and normal to free and clamped surfaces, respectively, and they interact elastically to form strings. Our method can be applied for rational design of tissue equivalents. Moreover our results indicate that the concept of contact guidance has to be reevaluated. We also suggest that cell-matrix contacts are upregulated by large effective stiffness in the environment because in this way, build-up of force is more efficient.Comment: Revtex, 7 pages, 4 Postscript files include

    A guideline for analyzing circadian wheel-running behavior in rodents under different lighting conditions

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    Most behavioral experiments within circadian research are based on the analysis of locomotor activity. This paper introduces scientists to chronobiology by explaining the basic terminology used within the field. Furthermore, it aims to assist in designing, carrying out, and evaluating wheel-running experiments with rodents, particularly mice. Since light is an easily applicable stimulus that provokes strong effects on clock phase, the paper focuses on the application of different lighting conditions

    Fluctuation theorem for currents and Schnakenberg network theory

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    A fluctuation theorem is proved for the macroscopic currents of a system in a nonequilibrium steady state, by using Schnakenberg network theory. The theorem can be applied, in particular, in reaction systems where the affinities or thermodynamic forces are defined globally in terms of the cycles of the graph associated with the stochastic process describing the time evolution.Comment: new version : 16 pages, 1 figure, to be published in Journal of Statistical Physic
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