Foaming binary solution mixtures of low molecular surfactant and polyelectrolyte

The lifetime of water solution foams of sodium dodecylsulfate (DDS, low molecular weight surfactant) and sodium carboxymethylcellulose (SCMC, polyelectrolyte) and their binary mixtures was experimentally investigated. The effects of ionic strength and acidity on the foam life were also determined. In binary solutions, a synergic effect of DDS and SCMC on the surface tension reduction, most likely resulting from the interaction of the surfactant with polymer, was found. The addition of NaCl into solution or increasing the ionic strength was found to decrease the surface tension and reduce interfacial mobility, hence increased foam lifetime. The relatively low lifetime of binary solution foams in acidic medium was attributed to the reaction between SCMC and acid, which resulted in relatively small reductions in the viscosity and consequently lowered the solution viscosity

Phraseological terminology in the English economic discourse

The research is devoted to the phraseological terms that are encountered in English economic texts. The research analyzed lexical-semantic, cognitive, pragmatic, and linguistic-cultural peculiarities of phraseological units. This research extracts 50 phraseological terms from papers in linguistics, mass media materials, business and professional literature on economics. They were distinguished through four phraseological and semantic fields: “monetary relations”, “buying and selling”, “business and management”, and “economic and production relations”. The dominant term “money” was determined. This term has a conceptual meaning, expressed by the positive and negative connotative marking. Phraseological units mean abstract things that take a shape within a specific context. This research explains the use of toponyms, anthroponyms, and zoonyms in phraseological units, as well as the presence of occasional lexemes. Other aspects that were addressed include the main origins of economic phraseological units (mythology, real-life events, characters and persons, literary works, religion), the ethnic, psychological, socio-political and cultural constants of the English economic sphere

E.Coli derived camelid antibodies as a sensor for P53 in saliva

Oral squamous cell carcinoma (OSCC) is a malignant tumor with 640,000 new cases annually in the world [1]. Saliva testing is non-invasive procedure that is capable to detect potential biomarkers for OSCC. It was shown that elevated level of p53 protein was identified in OSCC patients at different stages of the disease (ibid). Camelid antibodies containing only variable regions, nanobodies (VHH) and single-chain variable regions (scFv) with VH and VL, are becoming popular in many biological studies including diagnostic applications. It was identified that VL region alone showed higher affinity to p53 than VHH, and dimerization of VL region with another one increases the affinity up to 10 folds [2]. Camelid antibodies have similar affinity to its substrate as human antibodies and can be conjugated to other proteins without functional lose. They can be expressed and secreted in many organisms including E.Coli in high amount, which reduces the cost of antibodies production. Thus, the aim of this project is to design a biosensor, based on available sequence of antibodies, to detect p53 in saliva samples for OSCC diagnosis

Adapt and Make Accessible the Tri-N-Octylphosphine-Assisted Silar Method

To meet the needs of light-emitting equipment and related technology, LEDs, fluorescent solar concentrators, it is necessary to prepare high-quality quantum dots of semiconductors of the core-shell type. We conducted a set of sequential studies,testing existing QD synthesis techniques

Luminescent Downshifting Colloidal Quantum Dots for Large-Area Solar Cells

We show a practical application of colloidal quantum dots as a luminescent converters for operating large-area solar modules. For these purposes, we used quantum dots of the core/shell type with a high quantum luminescence yield (50%) embedded in polymer matrix.This work was supported by the Science Committee of Ministry of Education and Science Republic of Kazakhstan, IRN AP08856436

SOD2 gene polymorphism and muscle damage markers in elite athletes

Exercise-induced oxidative stress is a state that primarily occurs in athletes involved in high-intensity sports when pro-oxidants overwhelm the antioxidant defense system to oxidize proteins, lipids, and nucleic acids. During exercise, oxidative stress is linked to muscle metabolism and muscle damage, because exercise increases free radical production. The T allele of the Ala16Val (rs4880 C/T) polymorphism in the mitochondrial superoxide dismutase 2 (SOD2) gene has been reported to reduce SOD2 efficiency against oxidative stress. In the present study we tested the hypothesis that the SOD2 TT genotype would be underrepresented in elite athletes involved in high-intensity sports and associated with increased values of muscle and liver damage biomarkers. The study involved 2664 Caucasian (2262 Russian and 402 Polish) athletes. SOD2 genotype and allele frequencies were compared to 917 controls. Muscle and liver damage markers [creatine kinase (CK), creatinine, alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP)] were examined in serum from 1444 Russian athletes. The frequency of the SOD2 TT genotype (18.6%) was significantly lower in power/strength athletes (n = 524) compared to controls (25.0%, p = 0.0076) or athletes involved in low-intensity sports (n = 180; 33.9%, p < 0.0001). Furthermore, the SOD2 T allele was significantly associated with increased activity of CK (females: p = 0.0144) and creatinine level (females: p = 0.0276; males: p = 0.0135) in athletes. Our data show that the SOD2 TT genotype might be unfavorable for high-intensity athletic events

Clinical features of post-COVID-19 period. Results of the international register “Dynamic analysis of comorbidities in SARS-CoV-2 survivors (AKTIV SARS-CoV-2)”. Data from 6-month follow-up

Aim. To study the clinical course specifics of coronavirus disease 2019 (COVID-19) and comorbid conditions in COVID-19 survivors 3, 6, 12 months after recovery in the Eurasian region according to the AKTIV register. Material and methods.The AKTIV register was created at the initiative of the Eurasian Association of Therapists. The AKTIV register is divided into 2 parts: AKTIV 1 and AKTIV 2. The AKTIV 1 register currently includes 6300 patients, while in AKTIV 2 — 2770. Patients diagnosed with COVID-19 receiving in- and outpatient treatment have been anonymously included on the registry. The following 7 countries participated in the register: Russian Federation, Republic of Armenia, Republic of Belarus, Republic of Kazakhstan, Kyrgyz Republic, Republic of Moldova, Republic of Uzbekistan. This closed multicenter register with two nonoverlapping branches (in- and outpatient branch) provides 6 visits: 3 in-person visits during the acute period and 3 telephone calls after 3, 6, 12 months. Subject recruitment lasted from June 29, 2020 to October 29, 2020. Register will end on October 29, 2022. A total of 9 fragmentary analyzes of the registry data are planned. This fragment of the study presents the results of the post-hospitalization period in COVID-19 survivors after 3 and 6 months. Results. According to the AKTIV register, patients after COVID-19 are characterized by long-term persistent symptoms and frequent seeking for unscheduled medical care, including rehospitalizations. The most common causes of unplanned medical care are uncontrolled hypertension (HTN) and chronic coronary artery disease (CAD) and/or decompensated type 2 diabetes (T2D). During 3- and 6-month follow-up after hospitalization, 5,6% and 6,4% of patients were diagnosed with other diseases, which were more often presented by HTN, T2D, and CAD. The mortality rate of patients in the post-hospitalization period was 1,9% in the first 3 months and 0,2% for 4-6 months. The highest mortality rate was observed in the first 3 months in the group of patients with class II-IV heart failure, as well as in patients with cardiovascular diseases and cancer. In the pattern of death causes in the post-hospitalization period, following cardiovascular causes prevailed (31,8%): acute coronary syndrome, stroke, acute heart failure. Conclusion. According to the AKTIV register, the health status of patients after COVID-19 in a serious challenge for healthcare system, which requires planning adequate health system capacity to provide care to patients with COVID-19 in both acute and post-hospitalization period

Numerical investigation of heat transfer characteristics of pulverized coal in the combustion chambers of the heat energy centers of Kazakhstan

This article is devoted to the investigation of thermal characteristics of pulverized coal combustion process in the combustion chamber of the boiler BKZ-420. The greatest changes in the temperature distribution observed in the central part of the combustion chamber in the field of the fuel supply and the air fuel mixture are by burner holes. Carrying out the study of thermal characteristics is an important step during the modeling process of heat and mass transfer from the pulverized coal combustion, which allows to determine the temperature field throughout the volume of the combustion chamber and outlet. It has been determined the optimal combustion technology of high-energy fuel and the best structural parameters of the combustion chamber of the boiler BKZ-420 Almaty thermal power station that improve the wear resistance of power and reduce harmful emissions into the atmosphere (temperature decrease of the furnace wall, opposite the burners on the 3000C, ie 17.24% and secondary reduction of carbon monoxide concentration of CO at the outlet from the furnace at 15% carbon dioxide CO2 – 4.65%, and nitrogen dioxide NO2 – 14%)