Measurement of void fraction in pipes by neutron backscattering imaging technique

Void fraction of air-water two phase flow has been investigated using neutron backscatter imaging technique. A series of static measurements have been carried out for pipes having different radii and wall thicknesses. The obtained thermal neutron images successfully discriminate between the pipes having different void fraction. Linear relationship describes the values of backscattered thermal neutrons obtained from the reconstructed images and void fraction with some deviations in case of pipe four when buried at 10 cm depth. The obtained results indicate the reliability and effectiveness of the technique for studying void fraction of air-water two phase flow

Measurement of void fraction in pipes by neutron backscattering imaging technique

437-443Void fraction of air-water two phase flow has been investigated using neutron backscatter imaging technique. A series of static measurements have been carried out for pipes having different radii and wall thicknesses. The obtained thermal neutron images successfully discriminate between the pipes having different void fraction. Linear relationship describes the values of backscattered thermal neutrons obtained from the reconstructed images and void fraction with some deviations in case of pipe four when buried at 10 cm depth. The obtained results indicate the reliability and effectiveness of the technique for studying void fraction of air-water two phase flow.

Three-Dimensional Finite Element Analysis for Pressure on Flexible Wall Silos

A 3D finite element model (FEM) for predicting the distribution of lateral pressure in a square flexible walled steel silo during the filling phase was analyzed in this study. The numerical approach, developed using Abaqus software, predicts the stress state in bulk solids, as well as the pressures exerted on the silo walls. An elasto-plastic model using the Drucker–Prager criterion was employed to simulate the behavior of the granular materials. The FEM simulates the behavior of the bulk solid and its interaction with the silo’s wall and base using a surface-to-surface discretization model. The model’s predictions were validated by previous experimental measurements. The results revealed good agreement between the FEM predictions and the experimental measurements. The research confirms that the lateral pressure distribution is not uniform at any silo level. This highlights the fact that many available theories and current design codes are not accurate for flexible steel walls. As a result of the wall’s deformability, pressure regimes on the silo wall change significantly in the horizontal direction at any level. The results showed that the horizontal variations of lateral pressure change drastically with regard to wall stiffness. The FEM has been used to investigate the effect of critical parameters on wall pressure distribution, such as properties of bulk solids, wall thickness, and silo type, whether deep or flat

Drug discovery utilizing biotechnological methodologies and Northern Africa biodiversity

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HOTAIR expression and prognostic impact in acute myeloid leukemia patients

Abstract Background Acute myeloid leukemia (AML) is a disorder characterized by a rapid onset of symptoms attributable to bone marrow failure due to clonal proliferation of primitive hematopoietic stem cells or progenitor cells. Epigenetic abnormalities play an important role in the development and progression of acute leukemia. Long non-coding ribonucleic acid (lncRNA) plays an important role in epigenetic regulation. Homeobox (Hox) transcript antisense intergenic RNA (HOTAIR) is a lncRNA which has been determined to be a negative prognostic indicator in various solid-tumor patients. However, its role in hematopoietic tumors as AML is to be assessed. This study aimed at measuring lncRNA HOTAIR expression level on bone marrow (BM) mononuclear cells in newly diagnosed AML patients and correlating its expression with their outcome and different prognostic variables. This provides new prospective for a novel marker involved in development and progression of AML which can be used as a diagnostic marker and a target of therapy. The current study included 65 subjects divided into 35 newly diagnosed AML adult patients (before initiation of chemotherapy) and 30 non-leukemic adult patients who are candidates for BM aspiration for causes other than hematological malignancies as immune thrombocytopenic purpura and hypersplenism as controls. HOTAIR expression was measured on BM mononuclear cells by quantitative reverse transcription polymerase chain reaction (qRT-PCR). Results HOTAIR expression was found to be significantly upregulated in AML patients (probability (p) value = 0.000) and it can be used as a diagnostic biomarker of AML as confirmed by a significant difference between cases and controls using receiver operating characteristic curve (ROC) analysis. However, it was not significantly correlated with event free survival (EFS) or prognostic variables. Conclusion This study showed that the expression of HOTAIR is upregulated in de novo AML patients and can be used as a diagnostic marker. However, highly expressed HOTAIR is not associated with poor prognosis

Potential of staphylococcus xylosus strain for recovering nickel ions from aqueous solutions

The potential of bacterial biomass for the biosorption of heavy metals has investigated extensively. However, the bacterial species exhibited different affinities toward the heavy metals ions based on their differences in cell wall characteristics, structure and physiological status (living or dead cells). In this study, the potential of living and dead cells of Staphylococcus xylosus 222W for removal nickel ions from aqueous solution as a function for physiological status, nickel and biomass concentrations, time, pH and temperature was investigated. The pre-treatment of bacterial cells was performed by the heating at 100 ºC for 15 min. The removal experiments were conducted in the lab scale. The results revealed that the dead cells exhibited more efficiency in removing nickel ions than living cells at all investigated concentrations (2 to 10 mM). The biosorption efficiency (E %) increased with increasing in biomass cells to limit concentrations (0.1 to 1 g dry wt L-1). The maximum removal of nickel was 81.41 vs. 77.10 % by living and dead cells, respectively achieved after 9 and 10 hrs of the incubation period, respectively. The acidic conditions decrease the efficiency of metal removal, while the optimal removal was recorded at pH 8 for both biomass (living and dead cells). The maximum uptake capacity of S. xylosus 222W (living and dead cells) was recorded at 37oC, the percentage removed being 75.90 vs. 84.92 %, respectively. It can be concluded that S. xylosus 222W exhibited high potential and affinity to remove of nickel ions from aqueous solution